ID   YGCR_ECOLI              Reviewed;         259 AA.
AC   Q46908; Q2MA59;
DT   01-NOV-1997, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1997, sequence version 2.
DT   03-AUG-2022, entry version 127.
DE   RecName: Full=Putative electron transfer flavoprotein subunit YgcR;
GN   Name=ygcR; OrderedLocusNames=b2770, JW5441;
OS   Escherichia coli (strain K12).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Escherichia.
OX   NCBI_TaxID=83333;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=K12 / MG1655 / ATCC 47076;
RX   PubMed=9278503; DOI=10.1126/science.277.5331.1453;
RA   Blattner F.R., Plunkett G. III, Bloch C.A., Perna N.T., Burland V.,
RA   Riley M., Collado-Vides J., Glasner J.D., Rode C.K., Mayhew G.F.,
RA   Gregor J., Davis N.W., Kirkpatrick H.A., Goeden M.A., Rose D.J., Mau B.,
RA   Shao Y.;
RT   "The complete genome sequence of Escherichia coli K-12.";
RL   Science 277:1453-1462(1997).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=K12 / W3110 / ATCC 27325 / DSM 5911;
RX   PubMed=16738553; DOI=10.1038/msb4100049;
RA   Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S.,
RA   Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.;
RT   "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655
RT   and W3110.";
RL   Mol. Syst. Biol. 2:E1-E5(2006).
RN   [3]
RP   DISRUPTION PHENOTYPE.
RC   STRAIN=K12 / MC4100 / ATCC 35695 / DSM 6574;
RX   PubMed=22412352; DOI=10.1371/journal.pbio.1001281;
RA   Erental A., Sharon I., Engelberg-Kulka H.;
RT   "Two programmed cell death systems in Escherichia coli: an apoptotic-like
RT   death is inhibited by the mazEF-mediated death pathway.";
RL   PLoS Biol. 10:E1001281-E1001281(2012).
CC   -!- FUNCTION: May play a role in a redox process.
CC   -!- SUBUNIT: YgcQ and YgcR form a heterodimer. {ECO:0000305}.
CC   -!- DISRUPTION PHENOTYPE: Cells undergo an apoptotic-like death upon DNA
CC       damage characterized by membrane depolarization.
CC       {ECO:0000269|PubMed:22412352}.
CC   -!- SIMILARITY: Belongs to the ETF beta-subunit/FixA family. {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=AAA69280.1; Type=Frameshift; Evidence={ECO:0000305};
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DR   EMBL; U29579; AAA69280.1; ALT_FRAME; Genomic_DNA.
DR   EMBL; U00096; AAC75812.2; -; Genomic_DNA.
DR   EMBL; AP009048; BAE76847.1; -; Genomic_DNA.
DR   PIR; F65058; F65058.
DR   RefSeq; NP_417250.4; NC_000913.3.
DR   RefSeq; WP_001299652.1; NZ_LN832404.1.
DR   AlphaFoldDB; Q46908; -.
DR   SMR; Q46908; -.
DR   BioGRID; 4262284; 16.
DR   BioGRID; 851570; 2.
DR   IntAct; Q46908; 2.
DR   STRING; 511145.b2770; -.
DR   PaxDb; Q46908; -.
DR   PRIDE; Q46908; -.
DR   EnsemblBacteria; AAC75812; AAC75812; b2770.
DR   EnsemblBacteria; BAE76847; BAE76847; BAE76847.
DR   GeneID; 947240; -.
DR   KEGG; ecj:JW5441; -.
DR   KEGG; eco:b2770; -.
DR   PATRIC; fig|1411691.4.peg.3967; -.
DR   EchoBASE; EB2926; -.
DR   eggNOG; COG2086; Bacteria.
DR   HOGENOM; CLU_087555_1_0_6; -.
DR   InParanoid; Q46908; -.
DR   OMA; QEVRMNI; -.
DR   PhylomeDB; Q46908; -.
DR   BioCyc; EcoCyc:G7436-MON; -.
DR   PRO; PR:Q46908; -.
DR   Proteomes; UP000000318; Chromosome.
DR   Proteomes; UP000000625; Chromosome.
DR   GO; GO:0009055; F:electron transfer activity; IBA:GO_Central.
DR   CDD; cd01714; ETF_beta; 1.
DR   Gene3D; 3.40.50.620; -; 1.
DR   InterPro; IPR014730; ETF_a/b_N.
DR   InterPro; IPR012255; ETF_b.
DR   InterPro; IPR033948; ETF_beta_N.
DR   InterPro; IPR014729; Rossmann-like_a/b/a_fold.
DR   PANTHER; PTHR21294; PTHR21294; 1.
DR   Pfam; PF01012; ETF; 1.
DR   PIRSF; PIRSF000090; Beta-ETF; 1.
DR   SMART; SM00893; ETF; 1.
PE   3: Inferred from homology;
KW   Electron transport; FAD; Flavoprotein; Reference proteome; Transport.
FT   CHAIN           1..259
FT                   /note="Putative electron transfer flavoprotein subunit
FT                   YgcR"
FT                   /id="PRO_0000167900"
SQ   SEQUENCE   259 AA;  28720 MW;  DB8E1E7203E79E84 CRC64;
     MNILLAFKAE PDAGMLAEKE WQAAAQGKSG PDISLLRSLL GADEQAAAAL LLAQRKNGTP
     MSLTALSMGD ERALHWLRYL MALGFEEAVL LETAADLRFA PEFVARHIAE WQHQNPLDLI
     ITGCQSSEGQ NGQTPFLLAE MLGWPCFTQV ERFTLDALFI TLEQRTEHGL RCCRVRLPAV
     IAVRQCGEVA LPVPGMRQRM AAGKAEIIRK TVAAEMPAMQ CLQLARAEQR RGATLIDGQT
     VAEKAQKLWQ DYLRQRMQP