ID   YGCU_ECO57              Reviewed;         484 AA.
AC   Q8X7S0;
DT   16-APR-2002, integrated into UniProtKB/Swiss-Prot.
DT   01-MAR-2002, sequence version 1.
DT   03-AUG-2022, entry version 109.
DE   RecName: Full=Uncharacterized FAD-linked oxidoreductase YgcU;
DE            EC=1.-.-.-;
GN   Name=ygcU; OrderedLocusNames=Z4084, ECs3629;
OS   Escherichia coli O157:H7.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Escherichia.
OX   NCBI_TaxID=83334;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=O157:H7 / EDL933 / ATCC 700927 / EHEC;
RX   PubMed=11206551; DOI=10.1038/35054089;
RA   Perna N.T., Plunkett G. III, Burland V., Mau B., Glasner J.D., Rose D.J.,
RA   Mayhew G.F., Evans P.S., Gregor J., Kirkpatrick H.A., Posfai G.,
RA   Hackett J., Klink S., Boutin A., Shao Y., Miller L., Grotbeck E.J.,
RA   Davis N.W., Lim A., Dimalanta E.T., Potamousis K., Apodaca J.,
RA   Anantharaman T.S., Lin J., Yen G., Schwartz D.C., Welch R.A.,
RA   Blattner F.R.;
RT   "Genome sequence of enterohaemorrhagic Escherichia coli O157:H7.";
RL   Nature 409:529-533(2001).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=O157:H7 / Sakai / RIMD 0509952 / EHEC;
RX   PubMed=11258796; DOI=10.1093/dnares/8.1.11;
RA   Hayashi T., Makino K., Ohnishi M., Kurokawa K., Ishii K., Yokoyama K.,
RA   Han C.-G., Ohtsubo E., Nakayama K., Murata T., Tanaka M., Tobe T., Iida T.,
RA   Takami H., Honda T., Sasakawa C., Ogasawara N., Yasunaga T., Kuhara S.,
RA   Shiba T., Hattori M., Shinagawa H.;
RT   "Complete genome sequence of enterohemorrhagic Escherichia coli O157:H7 and
RT   genomic comparison with a laboratory strain K-12.";
RL   DNA Res. 8:11-22(2001).
CC   -!- SIMILARITY: Belongs to the FAD-binding oxidoreductase/transferase type
CC       4 family. {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=AAG57882.1; Type=Erroneous initiation; Evidence={ECO:0000305};
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DR   EMBL; AE005174; AAG57882.1; ALT_INIT; Genomic_DNA.
DR   EMBL; BA000007; BAB37052.1; -; Genomic_DNA.
DR   PIR; E91082; E91082.
DR   PIR; F85927; F85927.
DR   RefSeq; NP_311656.1; NC_002695.1.
DR   RefSeq; WP_000059304.1; NZ_SWKA01000005.1.
DR   AlphaFoldDB; Q8X7S0; -.
DR   SMR; Q8X7S0; -.
DR   STRING; 155864.EDL933_3947; -.
DR   EnsemblBacteria; AAG57882; AAG57882; Z4084.
DR   EnsemblBacteria; BAB37052; BAB37052; ECs_3629.
DR   GeneID; 914648; -.
DR   KEGG; ece:Z4084; -.
DR   KEGG; ecs:ECs_3629; -.
DR   PATRIC; fig|386585.9.peg.3793; -.
DR   eggNOG; COG0277; Bacteria.
DR   HOGENOM; CLU_017779_2_3_6; -.
DR   OMA; PRCHDEV; -.
DR   Proteomes; UP000000558; Chromosome.
DR   Proteomes; UP000002519; Chromosome.
DR   GO; GO:0071949; F:FAD binding; IEA:InterPro.
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR   Gene3D; 1.10.45.10; -; 1.
DR   Gene3D; 3.30.43.10; -; 1.
DR   Gene3D; 3.30.465.10; -; 1.
DR   InterPro; IPR016166; FAD-bd_PCMH.
DR   InterPro; IPR036318; FAD-bd_PCMH-like_sf.
DR   InterPro; IPR016167; FAD-bd_PCMH_sub1.
DR   InterPro; IPR016169; FAD-bd_PCMH_sub2.
DR   InterPro; IPR016164; FAD-linked_Oxase-like_C.
DR   InterPro; IPR004113; FAD-linked_oxidase_C.
DR   InterPro; IPR006094; Oxid_FAD_bind_N.
DR   InterPro; IPR016171; Vanillyl_alc_oxidase_C-sub2.
DR   Pfam; PF02913; FAD-oxidase_C; 1.
DR   Pfam; PF01565; FAD_binding_4; 1.
DR   SUPFAM; SSF55103; SSF55103; 1.
DR   SUPFAM; SSF56176; SSF56176; 1.
DR   PROSITE; PS51387; FAD_PCMH; 1.
PE   3: Inferred from homology;
KW   FAD; Flavoprotein; Oxidoreductase; Reference proteome.
FT   CHAIN           1..484
FT                   /note="Uncharacterized FAD-linked oxidoreductase YgcU"
FT                   /id="PRO_0000128184"
FT   DOMAIN          47..226
FT                   /note="FAD-binding PCMH-type"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00718"
SQ   SEQUENCE   484 AA;  53708 MW;  76259B4A0C6EA17C CRC64;
     MSLSRAAIVD QLKEIVGADR VITDETVLKK NSIDRFRKFP DIHGIYTLPI PAAVVKLGST
     EQVSRVLNFM NAHKINGVPR TGASATEGGL ETVVENSVVL DGSAMNQIIN IDIENMQATA
     QCGVPLEVLE NALREKGYTT GHSPQSKPLA QMGGLVATRS IGQFSTLYGA IEDMVVGLEA
     VLADGTVTRI KNVPRRAAGP DIRHIIIGNE GALCYITEVT VKIFKFTPEN NLFYGYILED
     MKTGFNILRE IMVEGYRPSI ARLYDAEDGT QHFTHFADGK CVLIFMAEGN PRIAKATGEG
     IAEIVARYPQ CQRVDSKLIE TWFNNLNWGP DKVAAERVQI LKTGNMGFTT EVSGCWSCIH
     EIYESVINRI RTEFPHADDI TMLGGHSSHS YQNGTNMYFV YDYNVVNCKP EEEIDKYHNP
     LNKIICEETI RLGGSMVHHH GIGKHRVHWS KLEHGSAWAL LEGLKKQFDP NGIMNTGTIY
     PIEK