ID   YGDC_SCHPO              Reviewed;         594 AA.
AC   O94569;
DT   13-NOV-2007, integrated into UniProtKB/Swiss-Prot.
DT   01-MAY-1999, sequence version 1.
DT   25-MAY-2022, entry version 119.
DE   RecName: Full=Uncharacterized transcriptional regulatory protein C1773.12;
GN   ORFNames=SPBC1773.12;
OS   Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina;
OC   Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae;
OC   Schizosaccharomyces.
OX   NCBI_TaxID=284812;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=972 / ATCC 24843;
RX   PubMed=11859360; DOI=10.1038/nature724;
RA   Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A.,
RA   Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S.,
RA   Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M.,
RA   Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S.,
RA   Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S.,
RA   Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D.,
RA   Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P.,
RA   Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K.,
RA   O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M.,
RA   Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N.,
RA   Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A.,
RA   Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R.,
RA   Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M.,
RA   Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A.,
RA   Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A.,
RA   Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H.,
RA   Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S.,
RA   Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C.,
RA   Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A.,
RA   Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M.,
RA   del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S.,
RA   Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R.,
RA   Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G.,
RA   Nurse P.;
RT   "The genome sequence of Schizosaccharomyces pombe.";
RL   Nature 415:871-880(2002).
RN   [2]
RP   SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
RX   PubMed=16823372; DOI=10.1038/nbt1222;
RA   Matsuyama A., Arai R., Yashiroda Y., Shirai A., Kamata A., Sekido S.,
RA   Kobayashi Y., Hashimoto A., Hamamoto M., Hiraoka Y., Horinouchi S.,
RA   Yoshida M.;
RT   "ORFeome cloning and global analysis of protein localization in the fission
RT   yeast Schizosaccharomyces pombe.";
RL   Nat. Biotechnol. 24:841-847(2006).
CC   -!- SUBCELLULAR LOCATION: Nucleus membrane {ECO:0000255|PROSITE-
CC       ProRule:PRU00227, ECO:0000269|PubMed:16823372}; Single-pass membrane
CC       protein {ECO:0000269|PubMed:16823372}. Nucleus, nucleolus
CC       {ECO:0000269|PubMed:16823372}.
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DR   EMBL; CU329671; CAA21917.1; -; Genomic_DNA.
DR   PIR; T39677; T39677.
DR   RefSeq; NP_595127.1; NM_001021034.2.
DR   AlphaFoldDB; O94569; -.
DR   SMR; O94569; -.
DR   BioGRID; 276674; 2.
DR   STRING; 4896.SPBC1773.12.1; -.
DR   PaxDb; O94569; -.
DR   PRIDE; O94569; -.
DR   EnsemblFungi; SPBC1773.12.1; SPBC1773.12.1:pep; SPBC1773.12.
DR   GeneID; 2540137; -.
DR   KEGG; spo:SPBC1773.12; -.
DR   PomBase; SPBC1773.12; -.
DR   VEuPathDB; FungiDB:SPBC1773.12; -.
DR   HOGENOM; CLU_458675_0_0_1; -.
DR   InParanoid; O94569; -.
DR   OMA; ELCESYH; -.
DR   PhylomeDB; O94569; -.
DR   PRO; PR:O94569; -.
DR   Proteomes; UP000002485; Chromosome II.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0000228; C:nuclear chromosome; IC:PomBase.
DR   GO; GO:0031965; C:nuclear membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0005730; C:nucleolus; HDA:PomBase.
DR   GO; GO:0005634; C:nucleus; HDA:PomBase.
DR   GO; GO:0000981; F:DNA-binding transcription factor activity, RNA polymerase II-specific; NAS:PomBase.
DR   GO; GO:0000978; F:RNA polymerase II cis-regulatory region sequence-specific DNA binding; ISM:PomBase.
DR   GO; GO:0008270; F:zinc ion binding; ISM:PomBase.
DR   GO; GO:0006357; P:regulation of transcription by RNA polymerase II; ISM:PomBase.
DR   GO; GO:0006351; P:transcription, DNA-templated; IEA:InterPro.
DR   CDD; cd00067; GAL4; 1.
DR   Gene3D; 4.10.240.10; -; 1.
DR   InterPro; IPR007219; Transcription_factor_dom_fun.
DR   InterPro; IPR001138; Zn2-C6_fun-type_DNA-bd.
DR   InterPro; IPR036864; Zn2-C6_fun-type_DNA-bd_sf.
DR   Pfam; PF04082; Fungal_trans; 1.
DR   Pfam; PF00172; Zn_clus; 1.
DR   SMART; SM00906; Fungal_trans; 1.
DR   SMART; SM00066; GAL4; 1.
DR   SUPFAM; SSF57701; SSF57701; 1.
DR   PROSITE; PS00463; ZN2_CY6_FUNGAL_1; 1.
DR   PROSITE; PS50048; ZN2_CY6_FUNGAL_2; 1.
PE   3: Inferred from homology;
KW   DNA-binding; Membrane; Metal-binding; Nucleus; Reference proteome;
KW   Transcription; Transcription regulation; Transmembrane;
KW   Transmembrane helix; Zinc.
FT   CHAIN           1..594
FT                   /note="Uncharacterized transcriptional regulatory protein
FT                   C1773.12"
FT                   /id="PRO_0000310381"
FT   TRANSMEM        501..523
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   DNA_BIND        11..38
FT                   /note="Zn(2)-C6 fungal-type"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00227"
SQ   SEQUENCE   594 AA;  69479 MW;  E9A5364BEC99B300 CRC64;
     MVPIKKISTA CDLCRQRKLR CNGELPKCQN CVVYSETCKY NKRKRVKKPN VDKDDPHIVV
     GQPPVKKSTA GITREYTEMI ELRNHIITLS KRSVNMESRI DDMLNLLNYD LSEKRETSNE
     IPSLVQQIQN CGFLIDEKMR RYPGIFQIHP KDYTMNDLFP QSFPTWISVY RNVPEKAWAN
     RCVEWYFRYI NSCWPLFDLE NFMDLFDNFY SDKEKTKGAW VVSFYAIMAL AVSRSKRKDK
     EKISKSLFST SWFLVQKPGF FLTARLDKIQ ALTIMIQFCA HLSLYNLCKV LCGQMCLMVK
     DLDLHKEATN PNVDIEVDEL NRRVFWTCYI FETTTSLIFG TPPELGDLEI DCQLPSMDVL
     PRFTESSQGG IVFCSEIQLT IIKNEIRKKI YKCLASASEE VYKEAVLSIR GKLIVWERNL
     PDELKQYYDV IKLNGTIPKN VDFENQHIFT ACVEIYLSYC ITQLYFYDPL TNYETCLEIA
     RKAADAIRSY FMVIEPIFKK ICYLWLFLYC PFTPFQILFS NILKMEKGTS DEKIEDLDRM
     YSLYRFFVEM KEINGEFADK LSRVALDCID AAEHYLELKS SVGSNIFELE SLLV