ID   YGEK_ECOLI              Reviewed;         147 AA.
AC   Q46791; Q2M9Y2; Q2M9Y3; Q46792;
DT   01-NOV-1997, integrated into UniProtKB/Swiss-Prot.
DT   07-NOV-2018, sequence version 3.
DT   25-MAY-2022, entry version 141.
DE   RecName: Full=Uncharacterized response regulatory protein YgeK;
GN   Name=ygeK; Synonyms=ygeL; OrderedLocusNames=b2856, JW5458/JW2824;
GN   ORFNames=b2855;
OS   Escherichia coli (strain K12).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Escherichia.
OX   NCBI_TaxID=83333;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=K12 / MG1655 / ATCC 47076;
RX   PubMed=9278503; DOI=10.1126/science.277.5331.1453;
RA   Blattner F.R., Plunkett G. III, Bloch C.A., Perna N.T., Burland V.,
RA   Riley M., Collado-Vides J., Glasner J.D., Rode C.K., Mayhew G.F.,
RA   Gregor J., Davis N.W., Kirkpatrick H.A., Goeden M.A., Rose D.J., Mau B.,
RA   Shao Y.;
RT   "The complete genome sequence of Escherichia coli K-12.";
RL   Science 277:1453-1462(1997).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=K12 / W3110 / ATCC 27325 / DSM 5911;
RX   PubMed=16738553; DOI=10.1038/msb4100049;
RA   Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S.,
RA   Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.;
RT   "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655
RT   and W3110.";
RL   Mol. Syst. Biol. 2:E1-E5(2006).
RN   [3]
RP   PHOSPHORYLATION.
RC   STRAIN=K12 / W3110 / ATCC 27325 / DSM 5911;
RX   PubMed=15522865; DOI=10.1074/jbc.m410104200;
RA   Yamamoto K., Hirao K., Oshima T., Aiba H., Utsumi R., Ishihama A.;
RT   "Functional characterization in vitro of all two-component signal
RT   transduction systems from Escherichia coli.";
RL   J. Biol. Chem. 280:1448-1456(2005).
CC   -!- PTM: Overexpressed protein is phosphorylated in vitro by non-cognate
CC       histidine kinases BarA and UhpB. {ECO:0000269|PubMed:15522865}.
CC   -!- MISCELLANEOUS: Lacks the N-terminal receiver domain usually found in
CC       response regulators, which is usally phosphorylated by the cognate
CC       histidine kinase. {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=AAA83037.1; Type=Erroneous initiation; Note=Extended N-terminus.; Evidence={ECO:0000305};
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DR   EMBL; U28375; AAA83037.1; ALT_INIT; Genomic_DNA.
DR   EMBL; U00096; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AP009048; BAE76923.1; -; Genomic_DNA.
DR   PIR; A65069; A65069.
DR   PIR; H65068; H65068.
DR   AlphaFoldDB; Q46791; -.
DR   SMR; Q46791; -.
DR   BioGRID; 4259232; 9.
DR   BioGRID; 4259233; 16.
DR   STRING; 316407.85675670; -.
DR   PRIDE; Q46791; -.
DR   EnsemblBacteria; BAE76923; BAE76923; BAE76923.
DR   KEGG; ecj:JW5458; -.
DR   EchoBASE; EB2856; -.
DR   eggNOG; COG2197; Bacteria.
DR   HOGENOM; CLU_000445_90_1_6; -.
DR   InParanoid; Q46791; -.
DR   OMA; THKLGAN; -.
DR   PhylomeDB; Q46791; -.
DR   PRO; PR:Q46791; -.
DR   Proteomes; UP000000318; Chromosome.
DR   Proteomes; UP000000625; Chromosome.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0000160; P:phosphorelay signal transduction system; IEA:InterPro.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:InterPro.
DR   CDD; cd06170; LuxR_C_like; 1.
DR   InterPro; IPR011006; CheY-like_superfamily.
DR   InterPro; IPR016032; Sig_transdc_resp-reg_C-effctor.
DR   InterPro; IPR001789; Sig_transdc_resp-reg_receiver.
DR   InterPro; IPR000792; Tscrpt_reg_LuxR_C.
DR   Pfam; PF00196; GerE; 1.
DR   PRINTS; PR00038; HTHLUXR.
DR   SMART; SM00421; HTH_LUXR; 1.
DR   SUPFAM; SSF46894; SSF46894; 1.
DR   SUPFAM; SSF52172; SSF52172; 1.
DR   PROSITE; PS00622; HTH_LUXR_1; 1.
DR   PROSITE; PS50043; HTH_LUXR_2; 1.
DR   PROSITE; PS50110; RESPONSE_REGULATORY; 1.
PE   1: Evidence at protein level;
KW   DNA-binding; Phosphoprotein; Reference proteome; Transcription;
KW   Transcription regulation.
FT   CHAIN           1..147
FT                   /note="Uncharacterized response regulatory protein YgeK"
FT                   /id="PRO_0000081366"
FT   DOMAIN          1..59
FT                   /note="Response regulatory"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00169"
FT   DOMAIN          78..143
FT                   /note="HTH luxR-type"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00411"
FT   DNA_BIND        102..121
FT                   /note="H-T-H motif"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00411"
SQ   SEQUENCE   147 AA;  16577 MW;  50512C8AB25B0E48 CRC64;
     MGAELVKWVK SHKIDAHIIT FVAKMPYIDS IKLLEAGAKG CVWKTSHPAK LNRAIDSISN
     GYTYFDSVHM DCEKISSRYS SDNQLTNRES EILQLIADGK TNKEIANFLQ LSRKTVETHR
     LNIMKKLDVH SGIELIKTAL RMGVCTI