YGEY_ECO57
ID YGEY_ECO57 Reviewed; 403 AA.
AC P65809; Q46805;
DT 11-OCT-2004, integrated into UniProtKB/Swiss-Prot.
DT 11-OCT-2004, sequence version 1.
DT 03-AUG-2022, entry version 106.
DE RecName: Full=Uncharacterized protein YgeY;
GN Name=ygeY; OrderedLocusNames=Z4211, ECs3745;
OS Escherichia coli O157:H7.
OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Escherichia.
OX NCBI_TaxID=83334;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=O157:H7 / EDL933 / ATCC 700927 / EHEC;
RX PubMed=11206551; DOI=10.1038/35054089;
RA Perna N.T., Plunkett G. III, Burland V., Mau B., Glasner J.D., Rose D.J.,
RA Mayhew G.F., Evans P.S., Gregor J., Kirkpatrick H.A., Posfai G.,
RA Hackett J., Klink S., Boutin A., Shao Y., Miller L., Grotbeck E.J.,
RA Davis N.W., Lim A., Dimalanta E.T., Potamousis K., Apodaca J.,
RA Anantharaman T.S., Lin J., Yen G., Schwartz D.C., Welch R.A.,
RA Blattner F.R.;
RT "Genome sequence of enterohaemorrhagic Escherichia coli O157:H7.";
RL Nature 409:529-533(2001).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=O157:H7 / Sakai / RIMD 0509952 / EHEC;
RX PubMed=11258796; DOI=10.1093/dnares/8.1.11;
RA Hayashi T., Makino K., Ohnishi M., Kurokawa K., Ishii K., Yokoyama K.,
RA Han C.-G., Ohtsubo E., Nakayama K., Murata T., Tanaka M., Tobe T., Iida T.,
RA Takami H., Honda T., Sasakawa C., Ogasawara N., Yasunaga T., Kuhara S.,
RA Shiba T., Hattori M., Shinagawa H.;
RT "Complete genome sequence of enterohemorrhagic Escherichia coli O157:H7 and
RT genomic comparison with a laboratory strain K-12.";
RL DNA Res. 8:11-22(2001).
CC -!- COFACTOR:
CC Name=Zn(2+); Xref=ChEBI:CHEBI:29105; Evidence={ECO:0000250};
CC Name=Co(2+); Xref=ChEBI:CHEBI:48828; Evidence={ECO:0000250};
CC Note=Binds 2 Zn(2+) or Co(2+) ions per subunit. {ECO:0000250};
CC -!- SIMILARITY: Belongs to the peptidase M20A family. {ECO:0000305}.
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DR EMBL; AE005174; AAG58001.1; -; Genomic_DNA.
DR EMBL; BA000007; BAB37168.1; -; Genomic_DNA.
DR PIR; A91097; A91097.
DR PIR; E85942; E85942.
DR RefSeq; NP_311772.1; NC_002695.1.
DR RefSeq; WP_001107125.1; NZ_SWKA01000005.1.
DR AlphaFoldDB; P65809; -.
DR SMR; P65809; -.
DR STRING; 155864.EDL933_4073; -.
DR MEROPS; M20.A08; -.
DR EnsemblBacteria; AAG58001; AAG58001; Z4211.
DR EnsemblBacteria; BAB37168; BAB37168; ECs_3745.
DR GeneID; 67415244; -.
DR GeneID; 916436; -.
DR KEGG; ece:Z4211; -.
DR KEGG; ecs:ECs_3745; -.
DR PATRIC; fig|386585.9.peg.3907; -.
DR eggNOG; COG0624; Bacteria.
DR HOGENOM; CLU_021802_2_1_6; -.
DR OMA; YGAKIMK; -.
DR Proteomes; UP000000558; Chromosome.
DR Proteomes; UP000002519; Chromosome.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0008237; F:metallopeptidase activity; IEA:UniProtKB-KW.
DR GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR InterPro; IPR001261; ArgE/DapE_CS.
DR InterPro; IPR036264; Bact_exopeptidase_dim_dom.
DR InterPro; IPR002933; Peptidase_M20.
DR InterPro; IPR017706; Peptidase_M20/DapE_YgeY.
DR InterPro; IPR011650; Peptidase_M20_dimer.
DR Pfam; PF07687; M20_dimer; 1.
DR Pfam; PF01546; Peptidase_M20; 1.
DR SUPFAM; SSF55031; SSF55031; 1.
DR TIGRFAMs; TIGR03526; selenium_YgeY; 1.
DR PROSITE; PS00758; ARGE_DAPE_CPG2_1; 1.
PE 3: Inferred from homology;
KW Cobalt; Hydrolase; Metal-binding; Metalloprotease; Protease;
KW Reference proteome; Zinc.
FT CHAIN 1..403
FT /note="Uncharacterized protein YgeY"
FT /id="PRO_0000185341"
FT ACT_SITE 83
FT /evidence="ECO:0000250"
FT ACT_SITE 148
FT /note="Proton acceptor"
FT /evidence="ECO:0000250"
FT BINDING 81
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /ligand_label="1"
FT /evidence="ECO:0000250"
FT BINDING 114
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /ligand_label="1"
FT /evidence="ECO:0000250"
FT BINDING 114
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /ligand_label="2"
FT /evidence="ECO:0000250"
FT BINDING 149
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /ligand_label="2"
FT /evidence="ECO:0000250"
FT BINDING 174
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /ligand_label="1"
FT /evidence="ECO:0000250"
FT BINDING 374
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /ligand_label="2"
FT /evidence="ECO:0000250"
SQ SEQUENCE 403 AA; 44804 MW; 87937D12244038B6 CRC64;
MAKNIPFKLI LEKAKDYQAD MTRFLRDMVA IPSESCDEKR VVHRIKEEME KVGFDKVEID
PMGNVLGYIG HGPRLVAMDA HIDTVGIGNI KNWDFDPYEG METDELIGGR GTSDQEGGMA
SMVYAGKIIK DLGLEDEYTL LVTGTVQEED CDGLCWQYII EQSGIRPEFV VSTEPTDCQV
YRGQRGRMEI RIDVQGVSCH GSAPERGDNA IFKMGPILGE LQELSQRLGY DEFLGKGTLT
VSEIFFTSPS RCAVADSCAV SIDRRLTWGE TWEGALDEIR ALPAVQKANA VVSMYNYDRP
SWTGLVYPTE CYFPTWKVEE DHFTVKALVN AYEGLFGKAP VVDKWTFSTN GVSIMGRHGI
PVIGFGPGKE PEAHAPNEKT WKSHLVTCAA MYAAIPLSWL ATE
