YGEY_ECOLI
ID YGEY_ECOLI Reviewed; 403 AA.
AC P65807; Q2M9W8; Q46805;
DT 11-OCT-2004, integrated into UniProtKB/Swiss-Prot.
DT 11-OCT-2004, sequence version 1.
DT 03-AUG-2022, entry version 120.
DE RecName: Full=Uncharacterized protein YgeY;
GN Name=ygeY; OrderedLocusNames=b2872, JW2840;
OS Escherichia coli (strain K12).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Escherichia.
OX NCBI_TaxID=83333;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=K12 / MG1655 / ATCC 47076;
RX PubMed=9278503; DOI=10.1126/science.277.5331.1453;
RA Blattner F.R., Plunkett G. III, Bloch C.A., Perna N.T., Burland V.,
RA Riley M., Collado-Vides J., Glasner J.D., Rode C.K., Mayhew G.F.,
RA Gregor J., Davis N.W., Kirkpatrick H.A., Goeden M.A., Rose D.J., Mau B.,
RA Shao Y.;
RT "The complete genome sequence of Escherichia coli K-12.";
RL Science 277:1453-1462(1997).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=K12 / W3110 / ATCC 27325 / DSM 5911;
RX PubMed=16738553; DOI=10.1038/msb4100049;
RA Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S.,
RA Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.;
RT "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655
RT and W3110.";
RL Mol. Syst. Biol. 2:E1-E5(2006).
CC -!- COFACTOR:
CC Name=Zn(2+); Xref=ChEBI:CHEBI:29105; Evidence={ECO:0000250};
CC Name=Co(2+); Xref=ChEBI:CHEBI:48828; Evidence={ECO:0000250};
CC Note=Binds 2 Zn(2+) or Co(2+) ions per subunit. {ECO:0000250};
CC -!- SIMILARITY: Belongs to the peptidase M20A family. {ECO:0000305}.
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DR EMBL; U28375; AAA83053.1; -; Genomic_DNA.
DR EMBL; U00096; AAC75910.1; -; Genomic_DNA.
DR EMBL; AP009048; BAE76938.1; -; Genomic_DNA.
DR PIR; H65070; H65070.
DR RefSeq; NP_417348.1; NC_000913.3.
DR RefSeq; WP_001107125.1; NZ_STEB01000001.1.
DR AlphaFoldDB; P65807; -.
DR SMR; P65807; -.
DR BioGRID; 4262323; 17.
DR IntAct; P65807; 10.
DR STRING; 511145.b2872; -.
DR MEROPS; M20.A08; -.
DR jPOST; P65807; -.
DR PaxDb; P65807; -.
DR PRIDE; P65807; -.
DR EnsemblBacteria; AAC75910; AAC75910; b2872.
DR EnsemblBacteria; BAE76938; BAE76938; BAE76938.
DR GeneID; 67415244; -.
DR GeneID; 947360; -.
DR KEGG; ecj:JW2840; -.
DR KEGG; eco:b2872; -.
DR PATRIC; fig|1411691.4.peg.3862; -.
DR EchoBASE; EB2867; -.
DR eggNOG; COG0624; Bacteria.
DR HOGENOM; CLU_021802_2_1_6; -.
DR InParanoid; P65807; -.
DR OMA; YGAKIMK; -.
DR PhylomeDB; P65807; -.
DR BioCyc; EcoCyc:G7491-MON; -.
DR PRO; PR:P65807; -.
DR Proteomes; UP000000318; Chromosome.
DR Proteomes; UP000000625; Chromosome.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0008237; F:metallopeptidase activity; IEA:UniProtKB-KW.
DR GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR InterPro; IPR001261; ArgE/DapE_CS.
DR InterPro; IPR036264; Bact_exopeptidase_dim_dom.
DR InterPro; IPR002933; Peptidase_M20.
DR InterPro; IPR017706; Peptidase_M20/DapE_YgeY.
DR InterPro; IPR011650; Peptidase_M20_dimer.
DR Pfam; PF07687; M20_dimer; 1.
DR Pfam; PF01546; Peptidase_M20; 1.
DR SUPFAM; SSF55031; SSF55031; 1.
DR TIGRFAMs; TIGR03526; selenium_YgeY; 1.
DR PROSITE; PS00758; ARGE_DAPE_CPG2_1; 1.
PE 3: Inferred from homology;
KW Cobalt; Hydrolase; Metal-binding; Metalloprotease; Protease;
KW Reference proteome; Zinc.
FT CHAIN 1..403
FT /note="Uncharacterized protein YgeY"
FT /id="PRO_0000185339"
FT ACT_SITE 83
FT /evidence="ECO:0000250"
FT ACT_SITE 148
FT /note="Proton acceptor"
FT /evidence="ECO:0000250"
FT BINDING 81
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /ligand_label="1"
FT /evidence="ECO:0000250"
FT BINDING 114
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /ligand_label="1"
FT /evidence="ECO:0000250"
FT BINDING 114
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /ligand_label="2"
FT /evidence="ECO:0000250"
FT BINDING 149
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /ligand_label="2"
FT /evidence="ECO:0000250"
FT BINDING 174
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /ligand_label="1"
FT /evidence="ECO:0000250"
FT BINDING 374
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /ligand_label="2"
FT /evidence="ECO:0000250"
SQ SEQUENCE 403 AA; 44804 MW; 87937D12244038B6 CRC64;
MAKNIPFKLI LEKAKDYQAD MTRFLRDMVA IPSESCDEKR VVHRIKEEME KVGFDKVEID
PMGNVLGYIG HGPRLVAMDA HIDTVGIGNI KNWDFDPYEG METDELIGGR GTSDQEGGMA
SMVYAGKIIK DLGLEDEYTL LVTGTVQEED CDGLCWQYII EQSGIRPEFV VSTEPTDCQV
YRGQRGRMEI RIDVQGVSCH GSAPERGDNA IFKMGPILGE LQELSQRLGY DEFLGKGTLT
VSEIFFTSPS RCAVADSCAV SIDRRLTWGE TWEGALDEIR ALPAVQKANA VVSMYNYDRP
SWTGLVYPTE CYFPTWKVEE DHFTVKALVN AYEGLFGKAP VVDKWTFSTN GVSIMGRHGI
PVIGFGPGKE PEAHAPNEKT WKSHLVTCAA MYAAIPLSWL ATE
