ID   YGFI_ECOLI              Reviewed;         298 AA.
AC   P52044; Q2M9S1;
DT   01-OCT-1996, integrated into UniProtKB/Swiss-Prot.
DT   16-NOV-2001, sequence version 2.
DT   03-AUG-2022, entry version 142.
DE   RecName: Full=Uncharacterized HTH-type transcriptional regulator YgfI;
GN   Name=ygfI; OrderedLocusNames=b2921, JW5476;
OS   Escherichia coli (strain K12).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Escherichia.
OX   NCBI_TaxID=83333;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=K12 / MG1655 / ATCC 47076;
RX   PubMed=9278503; DOI=10.1126/science.277.5331.1453;
RA   Blattner F.R., Plunkett G. III, Bloch C.A., Perna N.T., Burland V.,
RA   Riley M., Collado-Vides J., Glasner J.D., Rode C.K., Mayhew G.F.,
RA   Gregor J., Davis N.W., Kirkpatrick H.A., Goeden M.A., Rose D.J., Mau B.,
RA   Shao Y.;
RT   "The complete genome sequence of Escherichia coli K-12.";
RL   Science 277:1453-1462(1997).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=K12 / W3110 / ATCC 27325 / DSM 5911;
RX   PubMed=16738553; DOI=10.1038/msb4100049;
RA   Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S.,
RA   Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.;
RT   "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655
RT   and W3110.";
RL   Mol. Syst. Biol. 2:E1-E5(2006).
CC   -!- SIMILARITY: Belongs to the LysR transcriptional regulatory family.
CC       {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=AAA69088.1; Type=Erroneous initiation; Note=Extended N-terminus.; Evidence={ECO:0000305};
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DR   EMBL; U28377; AAA69088.1; ALT_INIT; Genomic_DNA.
DR   EMBL; U00096; AAC75958.2; -; Genomic_DNA.
DR   EMBL; AP009048; BAE76985.1; -; Genomic_DNA.
DR   PIR; H65076; H65076.
DR   RefSeq; NP_417396.4; NC_000913.3.
DR   RefSeq; WP_000350807.1; NZ_SSZK01000003.1.
DR   AlphaFoldDB; P52044; -.
DR   SMR; P52044; -.
DR   BioGRID; 4263514; 19.
DR   STRING; 511145.b2921; -.
DR   PaxDb; P52044; -.
DR   PRIDE; P52044; -.
DR   DNASU; 947401; -.
DR   EnsemblBacteria; AAC75958; AAC75958; b2921.
DR   EnsemblBacteria; BAE76985; BAE76985; BAE76985.
DR   GeneID; 947401; -.
DR   KEGG; ecj:JW5476; -.
DR   KEGG; eco:b2921; -.
DR   PATRIC; fig|1411691.4.peg.3811; -.
DR   EchoBASE; EB2801; -.
DR   eggNOG; COG0583; Bacteria.
DR   HOGENOM; CLU_081242_0_0_6; -.
DR   OMA; AMLDAYM; -.
DR   PhylomeDB; P52044; -.
DR   BioCyc; EcoCyc:G7518-MON; -.
DR   PRO; PR:P52044; -.
DR   Proteomes; UP000000318; Chromosome.
DR   Proteomes; UP000000625; Chromosome.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:DNA-binding transcription factor activity; IBA:GO_Central.
DR   GO; GO:0006974; P:cellular response to DNA damage stimulus; IEP:EcoliWiki.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IBA:GO_Central.
DR   Gene3D; 1.10.10.10; -; 1.
DR   InterPro; IPR005119; LysR_subst-bd.
DR   InterPro; IPR000847; Tscrpt_reg_HTH_LysR.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   Pfam; PF00126; HTH_1; 1.
DR   Pfam; PF03466; LysR_substrate; 1.
DR   SUPFAM; SSF46785; SSF46785; 1.
DR   PROSITE; PS50931; HTH_LYSR; 1.
PE   3: Inferred from homology;
KW   DNA-binding; Reference proteome; Transcription; Transcription regulation.
FT   CHAIN           1..298
FT                   /note="Uncharacterized HTH-type transcriptional regulator
FT                   YgfI"
FT                   /id="PRO_0000105794"
FT   DOMAIN          1..61
FT                   /note="HTH lysR-type"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00253"
FT   DNA_BIND        21..40
FT                   /note="H-T-H motif"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00253"
SQ   SEQUENCE   298 AA;  34674 MW;  14631042D131A27E CRC64;
     MDIFISKKMR NFILLAQTNN IARAAEKIHM TASPFGKSIA ALEEQIGYTL FTRKDNNISL
     NKAGQELYQK LFPVYQRLSA IDNEIHNSGR RSREIVIGID NTYPTIIFDQ LISLGDKYEG
     VTAQPVEFSE NGVIDNLFDR QLDFIISPQH VSARVQELEN LTISELPPLR LGFLVSRRYE
     ERQEQELLQE LPWLQMRFQN RANFEAMIDA NMRPCGINPT IIYRPYSFMA KISAVERGHF
     LTVIPHFAWR LVNPATLKYF DAPHRPMYMQ EYLYSIRNHR YTATMLQHIA EDRDGTSH