ID   YGFZ_VIBA3              Reviewed;         323 AA.
AC   B7VK90;
DT   28-JUL-2009, integrated into UniProtKB/Swiss-Prot.
DT   10-FEB-2009, sequence version 1.
DT   03-AUG-2022, entry version 66.
DE   RecName: Full=tRNA-modifying protein YgfZ {ECO:0000255|HAMAP-Rule:MF_01175};
GN   OrderedLocusNames=VS_2630;
OS   Vibrio atlanticus (strain LGP32) (Vibrio splendidus (strain Mel32)).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Vibrionales; Vibrionaceae;
OC   Vibrio.
OX   NCBI_TaxID=575788;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=LGP32;
RA   Mazel D., Le Roux F.;
RT   "Vibrio splendidus str. LGP32 complete genome.";
RL   Submitted (FEB-2009) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Folate-binding protein involved in regulating the level of
CC       ATP-DnaA and in the modification of some tRNAs. It is probably a key
CC       factor in regulatory networks that act via tRNA modification, such as
CC       initiation of chromosomal replication. {ECO:0000255|HAMAP-
CC       Rule:MF_01175}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_01175}.
CC   -!- SIMILARITY: Belongs to the tRNA-modifying YgfZ family.
CC       {ECO:0000255|HAMAP-Rule:MF_01175}.
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DR   EMBL; FM954972; CAV19849.1; -; Genomic_DNA.
DR   RefSeq; WP_012604793.1; NC_011753.2.
DR   AlphaFoldDB; B7VK90; -.
DR   SMR; B7VK90; -.
DR   STRING; 575788.VS_2630; -.
DR   EnsemblBacteria; CAV19849; CAV19849; VS_2630.
DR   KEGG; vsp:VS_2630; -.
DR   PATRIC; fig|575788.5.peg.3876; -.
DR   eggNOG; COG0354; Bacteria.
DR   HOGENOM; CLU_007884_6_1_6; -.
DR   OMA; VNFKKGC; -.
DR   OrthoDB; 1984573at2; -.
DR   Proteomes; UP000009100; Chromosome 1.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005542; F:folic acid binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0009451; P:RNA modification; IEA:InterPro.
DR   GO; GO:0008033; P:tRNA processing; IEA:UniProtKB-UniRule.
DR   HAMAP; MF_01175; tRNA_modifying_YgfZ; 1.
DR   InterPro; IPR029043; GcvT/YgfZ_C.
DR   InterPro; IPR023758; tRNA-modifying_YgfZ.
DR   InterPro; IPR045179; YgfZ/GcvT.
DR   InterPro; IPR017703; YgfZ/GcvT_CS.
DR   PANTHER; PTHR22602; PTHR22602; 1.
DR   SUPFAM; SSF101790; SSF101790; 1.
DR   TIGRFAMs; TIGR03317; ygfZ_signature; 1.
PE   3: Inferred from homology;
KW   Cytoplasm; Folate-binding; Reference proteome; tRNA processing.
FT   CHAIN           1..323
FT                   /note="tRNA-modifying protein YgfZ"
FT                   /id="PRO_1000164414"
FT   BINDING         29
FT                   /ligand="folate"
FT                   /ligand_id="ChEBI:CHEBI:62501"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01175"
FT   BINDING         182
FT                   /ligand="folate"
FT                   /ligand_id="ChEBI:CHEBI:62501"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01175"
SQ   SEQUENCE   323 AA;  35791 MW;  7242385DFA46B985 CRC64;
     MDWKNTFQPL AHTQNESLPE LMMTHVSDWS AITMIGDDKK SYLQGQVTCD VVTLPNDEST
     LGAHCDAKGK VWSIFRLFHH NGGYALMQPK SAIEVELVEI KKYAVFSKVD IEQTSDVVIG
     VMGASADQYI DSISESQGKV RVISGGTAVQ VSDNRWALLV TQEATEALVS SSTAEKVSEA
     LWQYHEILDA QPNLSKAEQN EHIPQALNLQ AIGGISFSKG CYTGQETVAR AKYRGMNKRE
     MRIVSGTSSD VLSLENTIEL ERSVGENWRG AGRLLNVYQF ADNQAIGLMV LPNNLDDDVQ
     LRLTAQPEQI WNILPLPYSL DEE