ID   YGFZ_VIBC1              Reviewed;         322 AA.
AC   A7MTS4;
DT   05-FEB-2008, integrated into UniProtKB/Swiss-Prot.
DT   02-OCT-2007, sequence version 1.
DT   03-AUG-2022, entry version 88.
DE   RecName: Full=tRNA-modifying protein YgfZ {ECO:0000255|HAMAP-Rule:MF_01175};
GN   OrderedLocusNames=VIBHAR_03546;
OS   Vibrio campbellii (strain ATCC BAA-1116).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Vibrionales; Vibrionaceae;
OC   Vibrio.
OX   NCBI_TaxID=2902295;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC BAA-1116 / BB120;
RG   The Vibrio harveyi Genome Sequencing Project;
RA   Bassler B., Clifton S.W., Fulton L., Delehaunty K., Fronick C.,
RA   Harrison M., Markivic C., Fulton R., Tin-Wollam A.-M., Shah N., Pepin K.,
RA   Nash W., Thiruvilangam P., Bhonagiri V., Waters C., Tu K.C., Irgon J.,
RA   Wilson R.K.;
RL   Submitted (AUG-2007) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Folate-binding protein involved in regulating the level of
CC       ATP-DnaA and in the modification of some tRNAs. It is probably a key
CC       factor in regulatory networks that act via tRNA modification, such as
CC       initiation of chromosomal replication. {ECO:0000255|HAMAP-
CC       Rule:MF_01175}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_01175}.
CC   -!- SIMILARITY: Belongs to the tRNA-modifying YgfZ family.
CC       {ECO:0000255|HAMAP-Rule:MF_01175}.
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DR   EMBL; CP000789; ABU72482.1; -; Genomic_DNA.
DR   RefSeq; WP_012128925.1; NC_022269.1.
DR   AlphaFoldDB; A7MTS4; -.
DR   SMR; A7MTS4; -.
DR   EnsemblBacteria; ABU72482; ABU72482; VIBHAR_03546.
DR   KEGG; vha:VIBHAR_03546; -.
DR   PATRIC; fig|338187.25.peg.2664; -.
DR   OMA; VNFKKGC; -.
DR   OrthoDB; 1984573at2; -.
DR   Proteomes; UP000008152; Chromosome I.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005542; F:folic acid binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0009451; P:RNA modification; IEA:InterPro.
DR   GO; GO:0008033; P:tRNA processing; IEA:UniProtKB-UniRule.
DR   HAMAP; MF_01175; tRNA_modifying_YgfZ; 1.
DR   InterPro; IPR029043; GcvT/YgfZ_C.
DR   InterPro; IPR023758; tRNA-modifying_YgfZ.
DR   InterPro; IPR045179; YgfZ/GcvT.
DR   InterPro; IPR017703; YgfZ/GcvT_CS.
DR   PANTHER; PTHR22602; PTHR22602; 1.
DR   SUPFAM; SSF101790; SSF101790; 1.
DR   TIGRFAMs; TIGR03317; ygfZ_signature; 1.
PE   3: Inferred from homology;
KW   Cytoplasm; Folate-binding; tRNA processing.
FT   CHAIN           1..322
FT                   /note="tRNA-modifying protein YgfZ"
FT                   /id="PRO_1000065779"
FT   BINDING         182
FT                   /ligand="folate"
FT                   /ligand_id="ChEBI:CHEBI:62501"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01175"
SQ   SEQUENCE   322 AA;  35288 MW;  3D375AEDD68395D5 CRC64;
     MEWQTRFSPL NLSTQDALPE LSISLLDNLG MITMVGDDKK SYLHGQVTCD VVSLEKDQSM
     LGAHCDAKGK VWSVFRLFHH NDGYAMVQPK SAIEVELKEI KKYAVFSKVT IEESSDIVLG
     VAGENADAFI STLNADSGEV RTVEGGTAVK VASNRWLLAL TAEAAQSLLE DSQATLTTHE
     LWTRFDIEAA LPYVAADAQN EHIPQALNVQ ALGGISFTKG CYTGQETVAR AKYRGTNKRA
     MYIVKGATAE ALGEGAIELE RSVGENWRSV GALLTHYQFS DNQAMGLIVL PNNLDDDTRL
     RLVTQPECEW EIAALPYSLD DE