ID   YGFZ_VIBVY              Reviewed;         324 AA.
AC   Q7MHM7;
DT   28-NOV-2006, integrated into UniProtKB/Swiss-Prot.
DT   28-NOV-2006, sequence version 2.
DT   03-AUG-2022, entry version 100.
DE   RecName: Full=tRNA-modifying protein YgfZ {ECO:0000255|HAMAP-Rule:MF_01175};
GN   OrderedLocusNames=VV2842;
OS   Vibrio vulnificus (strain YJ016).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Vibrionales; Vibrionaceae;
OC   Vibrio.
OX   NCBI_TaxID=196600;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=YJ016;
RX   PubMed=14656965; DOI=10.1101/gr.1295503;
RA   Chen C.-Y., Wu K.-M., Chang Y.-C., Chang C.-H., Tsai H.-C., Liao T.-L.,
RA   Liu Y.-M., Chen H.-J., Shen A.B.-T., Li J.-C., Su T.-L., Shao C.-P.,
RA   Lee C.-T., Hor L.-I., Tsai S.-F.;
RT   "Comparative genome analysis of Vibrio vulnificus, a marine pathogen.";
RL   Genome Res. 13:2577-2587(2003).
CC   -!- FUNCTION: Folate-binding protein involved in regulating the level of
CC       ATP-DnaA and in the modification of some tRNAs. It is probably a key
CC       factor in regulatory networks that act via tRNA modification, such as
CC       initiation of chromosomal replication. {ECO:0000255|HAMAP-
CC       Rule:MF_01175}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_01175}.
CC   -!- SIMILARITY: Belongs to the tRNA-modifying YgfZ family.
CC       {ECO:0000255|HAMAP-Rule:MF_01175}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=BAC95606.1; Type=Erroneous initiation; Evidence={ECO:0000305};
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DR   EMBL; BA000037; BAC95606.1; ALT_INIT; Genomic_DNA.
DR   RefSeq; WP_043877319.1; NC_005139.1.
DR   AlphaFoldDB; Q7MHM7; -.
DR   SMR; Q7MHM7; -.
DR   STRING; 672.VV93_v1c25500; -.
DR   EnsemblBacteria; BAC95606; BAC95606; BAC95606.
DR   KEGG; vvy:VV2842; -.
DR   PATRIC; fig|196600.6.peg.2830; -.
DR   eggNOG; COG0354; Bacteria.
DR   HOGENOM; CLU_007884_6_1_6; -.
DR   OMA; VNFKKGC; -.
DR   Proteomes; UP000002675; Chromosome I.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005542; F:folic acid binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0009451; P:RNA modification; IEA:InterPro.
DR   GO; GO:0008033; P:tRNA processing; IEA:UniProtKB-UniRule.
DR   HAMAP; MF_01175; tRNA_modifying_YgfZ; 1.
DR   InterPro; IPR006222; GCV_T_N.
DR   InterPro; IPR029043; GcvT/YgfZ_C.
DR   InterPro; IPR023758; tRNA-modifying_YgfZ.
DR   InterPro; IPR045179; YgfZ/GcvT.
DR   InterPro; IPR017703; YgfZ/GcvT_CS.
DR   PANTHER; PTHR22602; PTHR22602; 1.
DR   Pfam; PF01571; GCV_T; 1.
DR   SUPFAM; SSF101790; SSF101790; 1.
DR   TIGRFAMs; TIGR03317; ygfZ_signature; 1.
PE   3: Inferred from homology;
KW   Cytoplasm; Folate-binding; Reference proteome; tRNA processing.
FT   CHAIN           1..324
FT                   /note="tRNA-modifying protein YgfZ"
FT                   /id="PRO_0000262907"
FT   BINDING         184
FT                   /ligand="folate"
FT                   /ligand_id="ChEBI:CHEBI:62501"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01175"
SQ   SEQUENCE   324 AA;  35527 MW;  496561680F2B5C76 CRC64;
     MQSTQPIQRC ALGSQQALPE LAVSLLDNLG LITMTGNDKK SYLQGQVTCD VVSLEADQVT
     WGGHCDAKGK LWSAFRLFHY GDGYAMLQDK SAIDVELREL KKYAVFAKVE INVSDAILLG
     VCGVQAEQAI AKLTNNAEAA VATFAQGTAV KISPQRWLLV VDANQQDEVL AMLATAPLCD
     HALWDLYDIL EVSPRIPAFA QNEHIPQAVN LQAVNGISFK KGCYTGQETV ARAKYRGINK
     RALYRLSGAI EPSAPETTIS LERSVGDNWR AAGEALVSYH FDDGRATGLF VLPNDLEPET
     QFRLAGQSEQ LWQREPLPYS LDDE