YGH1_CAEEL
ID YGH1_CAEEL Reviewed; 535 AA.
AC Q22836;
DT 01-NOV-1997, integrated into UniProtKB/Swiss-Prot.
DT 01-NOV-1996, sequence version 1.
DT 03-AUG-2022, entry version 122.
DE RecName: Full=Uncharacterized protein T27F2.1;
GN ORFNames=T27F2.1;
OS Caenorhabditis elegans.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC Caenorhabditis.
OX NCBI_TaxID=6239;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Bristol N2;
RX PubMed=9851916; DOI=10.1126/science.282.5396.2012;
RG The C. elegans sequencing consortium;
RT "Genome sequence of the nematode C. elegans: a platform for investigating
RT biology.";
RL Science 282:2012-2018(1998).
CC -!- INTERACTION:
CC Q22836; Q18445: cyn-12; NbExp=4; IntAct=EBI-322121, EBI-2414398;
CC -!- SIMILARITY: Belongs to the SNW family. {ECO:0000305}.
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DR EMBL; Z74045; CAA98552.1; -; Genomic_DNA.
DR PIR; T25379; T25379.
DR RefSeq; NP_505950.1; NM_073549.7.
DR AlphaFoldDB; Q22836; -.
DR SMR; Q22836; -.
DR BioGRID; 44623; 32.
DR DIP; DIP-26404N; -.
DR IntAct; Q22836; 6.
DR STRING; 6239.T27F2.1; -.
DR iPTMnet; Q22836; -.
DR EPD; Q22836; -.
DR PaxDb; Q22836; -.
DR PeptideAtlas; Q22836; -.
DR EnsemblMetazoa; T27F2.1.1; T27F2.1.1; WBGene00004806.
DR GeneID; 179598; -.
DR KEGG; cel:CELE_T27F2.1; -.
DR CTD; 179598; -.
DR WormBase; T27F2.1; CE06519; WBGene00004806; skp-1.
DR eggNOG; KOG2441; Eukaryota.
DR GeneTree; ENSGT00390000010423; -.
DR HOGENOM; CLU_006601_2_0_1; -.
DR InParanoid; Q22836; -.
DR OMA; WRDSNTL; -.
DR OrthoDB; 1455730at2759; -.
DR PhylomeDB; Q22836; -.
DR Reactome; R-CEL-2173795; Downregulation of SMAD2/3:SMAD4 transcriptional activity.
DR Reactome; R-CEL-72163; mRNA Splicing - Major Pathway.
DR PRO; PR:Q22836; -.
DR Proteomes; UP000001940; Chromosome V.
DR Bgee; WBGene00004806; Expressed in germ line (C elegans) and 4 other tissues.
DR GO; GO:0005681; C:spliceosomal complex; IEA:InterPro.
DR GO; GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.
DR GO; GO:0007281; P:germ cell development; IMP:WormBase.
DR GO; GO:0040011; P:locomotion; IMP:WormBase.
DR GO; GO:0042303; P:molting cycle; IMP:WormBase.
DR GO; GO:0000398; P:mRNA splicing, via spliceosome; IEA:InterPro.
DR GO; GO:0002119; P:nematode larval development; IMP:WormBase.
DR GO; GO:0018991; P:oviposition; IMP:WormBase.
DR GO; GO:0045893; P:positive regulation of transcription, DNA-templated; ISS:WormBase.
DR GO; GO:0010468; P:regulation of gene expression; IMP:WormBase.
DR GO; GO:0060065; P:uterus development; IMP:WormBase.
DR GO; GO:0040025; P:vulval development; IMP:WormBase.
DR InterPro; IPR017862; SKI-int_prot_SKIP.
DR InterPro; IPR004015; SKI-int_prot_SKIP_SNW-dom.
DR PANTHER; PTHR12096; PTHR12096; 1.
DR Pfam; PF02731; SKIP_SNW; 1.
PE 1: Evidence at protein level;
KW Reference proteome.
FT CHAIN 1..535
FT /note="Uncharacterized protein T27F2.1"
FT /id="PRO_0000084829"
FT REGION 1..58
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 179..342
FT /note="SNW"
FT REGION 211..254
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 313..353
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 376..416
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 421..440
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 508..535
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 376..395
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 509..535
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 535 AA; 60197 MW; 7DC7E46185A72716 CRC64;
MSMKLRDILP APVAADEAAS QIRRDPWFGG RDNEPSAALV SKEPPPYGKR TSFRPRGPED
FGDGGAFPEI HVAQFPLGLG LGDMRGKPEN TLALQYGTDG KLQHDAIARI GHVKDKVVYS
KLNDMKAKTW NEDDDDIQKP DDDAVIDATE KTRMALEKIV NSKVASALPV RHADKLAPAQ
YIRYTPSQQN GAAGSQQRII RMVEEQKDPM EPPKFKINQK IPRAPPSPPA PVMHSPPRKM
TAKDQNDWKI PPCISNWKNP KGFTVGLDKR LAADGRGLQQ THINENFAKL ADALYIADRK
AREEVETRAQ LERRVAQNKK SEQEAKMAEA AAKARQERSA MRRKDDEDDE QVKVREEIRR
DRLDDIRKER NIARSRPDKA DKLRKERERD ISEKIVLGLP DTNQKRTGEP QFDQRLFDKT
QGLDSGAMDD DTYNPYDAAW RGGDSVQQHV YRPSKNLDND VYGGDLDKII EQKNRFVADK
GFSGAEGSSR GSGPVQFEKD QDVFGLSSLF EHTKEKKRGG DGGDSRGESK RSRRD