YGHG_ECOLI
ID YGHG_ECOLI Reviewed; 136 AA.
AC Q46835; Q2M9M4;
DT 01-DEC-2000, integrated into UniProtKB/Swiss-Prot.
DT 01-NOV-1996, sequence version 1.
DT 03-AUG-2022, entry version 120.
DE RecName: Full=Lipoprotein YghG;
DE AltName: Full=Putative pilotin YghG {ECO:0000305};
DE Flags: Precursor;
GN Name=yghG; OrderedLocusNames=b2971, JW2938;
OS Escherichia coli (strain K12).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Escherichia.
OX NCBI_TaxID=83333;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=K12 / MG1655 / ATCC 47076;
RX PubMed=9278503; DOI=10.1126/science.277.5331.1453;
RA Blattner F.R., Plunkett G. III, Bloch C.A., Perna N.T., Burland V.,
RA Riley M., Collado-Vides J., Glasner J.D., Rode C.K., Mayhew G.F.,
RA Gregor J., Davis N.W., Kirkpatrick H.A., Goeden M.A., Rose D.J., Mau B.,
RA Shao Y.;
RT "The complete genome sequence of Escherichia coli K-12.";
RL Science 277:1453-1462(1997).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=K12 / W3110 / ATCC 27325 / DSM 5911;
RX PubMed=16738553; DOI=10.1038/msb4100049;
RA Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S.,
RA Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.;
RT "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655
RT and W3110.";
RL Mol. Syst. Biol. 2:E1-E5(2006).
RN [3]
RP PROTEIN SEQUENCE OF 73-91, IDENTIFICATION, AND INDUCTION BY HEAT SHOCK.
RC STRAIN=K12 / MG1655 / ATCC 47076;
RX PubMed=29039649; DOI=10.1021/acs.biochem.7b00864;
RA Yuan P., D'Lima N.G., Slavoff S.A.;
RT "Comparative membrane proteomics reveals a nonannotated E. coli heat shock
RT protein.";
RL Biochemistry 57:56-60(2018).
CC -!- FUNCTION: Involved in a type II secretion system (T2SS, formerly
CC general secretion pathway, GSP) for the export of folded proteins
CC across the outer membrane. In a functional T2SS this subunit helps
CC assemble the outer membrane channel. {ECO:0000305}.
CC -!- SUBCELLULAR LOCATION: Cell outer membrane
CC {ECO:0000250|UniProtKB:E3PJ88}; Lipid-anchor {ECO:0000255|PROSITE-
CC ProRule:PRU00303}.
CC -!- INDUCTION: By heat shock (shift from 30 to 45 degrees Celsius) (at
CC protein level). {ECO:0000269|PubMed:29039649}.
CC -!- MISCELLANEOUS: In many other E.coli strains this gene is part of a type
CC II secretion system, but in MG1655 the locus is missing a number of
CC genes. {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the GspS/AspS pilotin family. {ECO:0000305}.
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DR EMBL; U28377; AAA69138.1; -; Genomic_DNA.
DR EMBL; U00096; AAC76007.1; -; Genomic_DNA.
DR EMBL; AP009048; BAE77032.1; -; Genomic_DNA.
DR PIR; A65083; A65083.
DR RefSeq; NP_417445.1; NC_000913.3.
DR RefSeq; WP_001324279.1; NZ_LN832404.1.
DR AlphaFoldDB; Q46835; -.
DR SMR; Q46835; -.
DR BioGRID; 4262363; 12.
DR STRING; 511145.b2971; -.
DR PaxDb; Q46835; -.
DR PRIDE; Q46835; -.
DR EnsemblBacteria; AAC76007; AAC76007; b2971.
DR EnsemblBacteria; BAE77032; BAE77032; BAE77032.
DR GeneID; 947470; -.
DR KEGG; ecj:JW2938; -.
DR KEGG; eco:b2971; -.
DR PATRIC; fig|1411691.4.peg.3760; -.
DR EchoBASE; EB2815; -.
DR eggNOG; ENOG502ZG1M; Bacteria.
DR HOGENOM; CLU_156494_0_0_6; -.
DR OMA; HQANKIN; -.
DR BioCyc; EcoCyc:G7538-MON; -.
DR PRO; PR:Q46835; -.
DR Proteomes; UP000000318; Chromosome.
DR Proteomes; UP000000625; Chromosome.
DR GO; GO:0009279; C:cell outer membrane; ISS:EcoCyc.
DR GO; GO:0006974; P:cellular response to DNA damage stimulus; IEP:EcoliWiki.
DR InterPro; IPR016502; T2SSS_2.
DR Pfam; PF16549; T2SSS_2; 1.
DR PIRSF; PIRSF007010; UCP007010; 1.
DR PROSITE; PS51257; PROKAR_LIPOPROTEIN; 1.
PE 1: Evidence at protein level;
KW Cell outer membrane; Direct protein sequencing; Lipoprotein; Membrane;
KW Palmitate; Reference proteome; Signal; Stress response.
FT SIGNAL 1..24
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00303"
FT CHAIN 25..136
FT /note="Lipoprotein YghG"
FT /id="PRO_0000013898"
FT LIPID 25
FT /note="N-palmitoyl cysteine"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00303"
FT LIPID 25
FT /note="S-diacylglycerol cysteine"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00303"
SQ SEQUENCE 136 AA; 14670 MW; 8CF586EC327D869A CRC64;
MSIKQMPGRV LISLLLSVTG LLSGCASHNE NASLLAKKQA QNISQNLPIK SAGYTLVLAQ
SSGTTVKMTI ISEAGTQTTQ TPDAFLTSYQ RQMCADPTVK LMITEGINYS ITINDTRTGN
QYQRKLDRTT CGIVKA
