ID   YGHQ_ECOLI              Reviewed;         355 AA.
AC   Q46841; Q2M9L2;
DT   01-NOV-1997, integrated into UniProtKB/Swiss-Prot.
DT   11-JUL-2001, sequence version 2.
DT   03-AUG-2022, entry version 124.
DE   RecName: Full=Inner membrane protein YghQ;
GN   Name=yghQ; OrderedLocusNames=b2983, JW5490;
OS   Escherichia coli (strain K12).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Escherichia.
OX   NCBI_TaxID=83333;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=K12 / MG1655 / ATCC 47076;
RX   PubMed=9278503; DOI=10.1126/science.277.5331.1453;
RA   Blattner F.R., Plunkett G. III, Bloch C.A., Perna N.T., Burland V.,
RA   Riley M., Collado-Vides J., Glasner J.D., Rode C.K., Mayhew G.F.,
RA   Gregor J., Davis N.W., Kirkpatrick H.A., Goeden M.A., Rose D.J., Mau B.,
RA   Shao Y.;
RT   "The complete genome sequence of Escherichia coli K-12.";
RL   Science 277:1453-1462(1997).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=K12 / W3110 / ATCC 27325 / DSM 5911;
RX   PubMed=16738553; DOI=10.1038/msb4100049;
RA   Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S.,
RA   Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.;
RT   "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655
RT   and W3110.";
RL   Mol. Syst. Biol. 2:E1-E5(2006).
RN   [3]
RP   TOPOLOGY [LARGE SCALE ANALYSIS].
RC   STRAIN=K12 / MG1655 / ATCC 47076;
RX   PubMed=15919996; DOI=10.1126/science.1109730;
RA   Daley D.O., Rapp M., Granseth E., Melen K., Drew D., von Heijne G.;
RT   "Global topology analysis of the Escherichia coli inner membrane
RT   proteome.";
RL   Science 308:1321-1323(2005).
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane; Multi-pass membrane protein.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=AAA69150.1; Type=Erroneous initiation; Evidence={ECO:0000305};
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DR   EMBL; U28377; AAA69150.1; ALT_INIT; Genomic_DNA.
DR   EMBL; U00096; AAT48159.1; -; Genomic_DNA.
DR   EMBL; AP009048; BAE77044.1; -; Genomic_DNA.
DR   RefSeq; WP_000896895.1; NZ_CP014272.1.
DR   RefSeq; YP_026192.1; NC_000913.3.
DR   AlphaFoldDB; Q46841; -.
DR   SMR; Q46841; -.
DR   BioGRID; 4262371; 8.
DR   DIP; DIP-12208N; -.
DR   IntAct; Q46841; 1.
DR   STRING; 511145.b2983; -.
DR   PaxDb; Q46841; -.
DR   PRIDE; Q46841; -.
DR   EnsemblBacteria; AAT48159; AAT48159; b2983.
DR   EnsemblBacteria; BAE77044; BAE77044; BAE77044.
DR   GeneID; 947716; -.
DR   KEGG; ecj:JW5490; -.
DR   KEGG; eco:b2983; -.
DR   PATRIC; fig|1411691.4.peg.3747; -.
DR   EchoBASE; EB2823; -.
DR   eggNOG; COG2244; Bacteria.
DR   HOGENOM; CLU_047009_0_0_6; -.
DR   OMA; FQSWQTV; -.
DR   BioCyc; EcoCyc:G7549-MON; -.
DR   BioCyc; MetaCyc:G7549-MON; -.
DR   PRO; PR:Q46841; -.
DR   Proteomes; UP000000318; Chromosome.
DR   Proteomes; UP000000625; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IDA:EcoCyc.
DR   InterPro; IPR002797; Polysacc_synth.
DR   Pfam; PF01943; Polysacc_synt; 1.
PE   1: Evidence at protein level;
KW   Cell inner membrane; Cell membrane; Membrane; Reference proteome;
KW   Transmembrane; Transmembrane helix.
FT   CHAIN           1..355
FT                   /note="Inner membrane protein YghQ"
FT                   /id="PRO_0000169389"
FT   TOPO_DOM        1..37
FT                   /note="Periplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        38..58
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        59..100
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        101..121
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        122..134
FT                   /note="Periplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        135..155
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        156..177
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        178..198
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        199..261
FT                   /note="Periplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        262..282
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        283..323
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        324..344
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        345..355
FT                   /note="Periplasmic"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   355 AA;  38533 MW;  47A6482C8C398D1D CRC64;
     MAGFNIKHWF ADGAFRTIIR NSAWLGSSNV VSALLGLLAL SCAGKGMTPA MFGVLVIVQS
     YAKSISDFIK FQTWQLVVQY GTPALTNNNP QQFRNVVSFS FSLDIVSGAV AIVGGIALLP
     FLSHSLGLDD QSFWLAALYC TLIPSMASST PTGILRAVDR FDLIAVQQAT KPFLRAAGSV
     VAWYFDFGFA GFVIAWYVSN LVGGTMYWWF AARELRRRNI HNAFKLNLFE SARYIKGAWS
     FVWSTNIAHS IWSARNSCST VLVGIVLGPA AAGLFKIAMT FFDAAGTPAG LLGKSFYPEV
     MRLDPRTTRP WLLGVKSGLL AGGIGILVAL AVLIVGKPLI SLVFGVKYLE AYDLI