YGI4_SCHPO
ID YGI4_SCHPO Reviewed; 741 AA.
AC Q9Y7K6;
DT 13-NOV-2007, integrated into UniProtKB/Swiss-Prot.
DT 01-NOV-1999, sequence version 1.
DT 03-AUG-2022, entry version 124.
DE RecName: Full=Uncharacterized RING finger protein C2A9.04c;
GN ORFNames=SPBC2A9.04c;
OS Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina;
OC Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae;
OC Schizosaccharomyces.
OX NCBI_TaxID=284812;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=972 / ATCC 24843;
RX PubMed=11859360; DOI=10.1038/nature724;
RA Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A.,
RA Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S.,
RA Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M.,
RA Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S.,
RA Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S.,
RA Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D.,
RA Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P.,
RA Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K.,
RA O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M.,
RA Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N.,
RA Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A.,
RA Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R.,
RA Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M.,
RA Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A.,
RA Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A.,
RA Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H.,
RA Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S.,
RA Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C.,
RA Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A.,
RA Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M.,
RA del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S.,
RA Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R.,
RA Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G.,
RA Nurse P.;
RT "The genome sequence of Schizosaccharomyces pombe.";
RL Nature 415:871-880(2002).
RN [2]
RP SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
RX PubMed=16823372; DOI=10.1038/nbt1222;
RA Matsuyama A., Arai R., Yashiroda Y., Shirai A., Kamata A., Sekido S.,
RA Kobayashi Y., Hashimoto A., Hamamoto M., Hiraoka Y., Horinouchi S.,
RA Yoshida M.;
RT "ORFeome cloning and global analysis of protein localization in the fission
RT yeast Schizosaccharomyces pombe.";
RL Nat. Biotechnol. 24:841-847(2006).
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000269|PubMed:16823372}.
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DR EMBL; CU329671; CAB39846.1; -; Genomic_DNA.
DR PIR; T40095; T40095.
DR RefSeq; NP_596213.1; NM_001022132.2.
DR AlphaFoldDB; Q9Y7K6; -.
DR SMR; Q9Y7K6; -.
DR BioGRID; 277008; 27.
DR STRING; 4896.SPBC2A9.04c.1; -.
DR iPTMnet; Q9Y7K6; -.
DR MaxQB; Q9Y7K6; -.
DR PaxDb; Q9Y7K6; -.
DR PRIDE; Q9Y7K6; -.
DR EnsemblFungi; SPBC2A9.04c.1; SPBC2A9.04c.1:pep; SPBC2A9.04c.
DR GeneID; 2540480; -.
DR KEGG; spo:SPBC2A9.04c; -.
DR PomBase; SPBC2A9.04c; -.
DR VEuPathDB; FungiDB:SPBC2A9.04c; -.
DR eggNOG; KOG0800; Eukaryota.
DR HOGENOM; CLU_346177_0_0_1; -.
DR InParanoid; Q9Y7K6; -.
DR OMA; RKEVPHE; -.
DR PhylomeDB; Q9Y7K6; -.
DR PRO; PR:Q9Y7K6; -.
DR Proteomes; UP000002485; Chromosome II.
DR GO; GO:0005634; C:nucleus; IDA:PomBase.
DR GO; GO:0061630; F:ubiquitin protein ligase activity; IMP:PomBase.
DR GO; GO:0008270; F:zinc ion binding; ISM:PomBase.
DR GO; GO:0071629; P:cytoplasm protein quality control by the ubiquitin-proteasome system; IMP:PomBase.
DR GO; GO:0000209; P:protein polyubiquitination; IMP:PomBase.
DR GO; GO:0006511; P:ubiquitin-dependent protein catabolic process; IMP:PomBase.
DR Gene3D; 3.30.40.10; -; 1.
DR InterPro; IPR001841; Znf_RING.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR Pfam; PF13639; zf-RING_2; 1.
DR SMART; SM00184; RING; 2.
DR PROSITE; PS50089; ZF_RING_2; 1.
PE 4: Predicted;
KW Metal-binding; Nucleus; Reference proteome; Repeat; Zinc; Zinc-finger.
FT CHAIN 1..741
FT /note="Uncharacterized RING finger protein C2A9.04c"
FT /id="PRO_0000310484"
FT ZN_FING 107..150
FT /note="RING-type 1; degenerate"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00175"
FT ZN_FING 687..736
FT /note="RING-type 2; degenerate"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00175"
FT REGION 1..50
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 177..214
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 238..387
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 500..543
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 561..619
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 638..688
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 713..741
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..16
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 31..50
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 177..211
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 238..265
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 275..345
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 359..387
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 501..543
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 566..592
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 599..619
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 638..662
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 727..741
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 741 AA; 80385 MW; 9E049DC0049FAE0C CRC64;
MDSNTNENNS HASSNERQSS EGHDDYLNRN PNSEATEGEE GTHPTTGTQP VAFSIGTMFI
ITPQANFEGG ENDPFANPFQ PPVKRAVKEA WDSFEPLSND QLMDLTCPIC YDDMNENDEK
QATKMPCGHI FGKNCLQKWL ENHCTCPLCR KEVPHETVGS AHPPILFIIP HSHTLRGNQG
NTAVSQENAS NGVHSDFHPS EELNNANTDG RTGVDEPARQ LHRIAFNRIR FILAPNRSAT
NTPVENTHPE NPDSNTSTPT TRSEPLAGEG ASIDAENASS RQETTPSDSR PSTLTSLFNA
FFSSMPDRPS SNEPMTSNLT SNSGSMTNST STDLPTSNLP SQNAPARPVE PSPSIQPPNL
LNLPTASPES TSWLPGSQTN IPANTNRSER PFTQLMTFHG LPSLADLPAV LESMFRPSGN
NNLLNLNGIF HPDHNAQTEN GQTLPENTDD TNSNATSAVP NLQNLNQQNA VTMGTNTPNN
GSSPAVHPVI HIYLSRPPLQ PAVSEQETPS EAVSREGTRS TDATMEDSSR PPSNGSFQGP
GITHLSEMGQ RILQRFQEEM ENRMNQTRSE SSTPAQQSAA GSSINVDTAG RQPSDEINIP
GEYENSSEVA GSRNQTPTHS SIAVDTLSNV AVDQPAISTP SDVVGSDAGD TSKVSSGTST
PRMAAPIARR SNRHHPYSRP SSTRPQCQLE DQGICDPNDR FVHFECGHSV HERCQQSTSN
SENQMDEEIG ECPKCRNEEH K