YGI7_SCHPO
ID YGI7_SCHPO Reviewed; 246 AA.
AC Q9Y7K9;
DT 15-JAN-2008, integrated into UniProtKB/Swiss-Prot.
DT 22-FEB-2012, sequence version 3.
DT 03-AUG-2022, entry version 102.
DE RecName: Full=PARP-type zinc finger-containing protein C2A9.07c;
GN ORFNames=SPBC2A9.07c;
OS Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina;
OC Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae;
OC Schizosaccharomyces.
OX NCBI_TaxID=284812;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=972 / ATCC 24843;
RX PubMed=11859360; DOI=10.1038/nature724;
RA Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A.,
RA Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S.,
RA Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M.,
RA Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S.,
RA Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S.,
RA Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D.,
RA Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P.,
RA Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K.,
RA O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M.,
RA Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N.,
RA Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A.,
RA Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R.,
RA Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M.,
RA Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A.,
RA Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A.,
RA Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H.,
RA Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S.,
RA Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C.,
RA Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A.,
RA Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M.,
RA del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S.,
RA Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R.,
RA Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G.,
RA Nurse P.;
RT "The genome sequence of Schizosaccharomyces pombe.";
RL Nature 415:871-880(2002).
RN [2]
RP REVISION OF GENE MODEL.
RX PubMed=21511999; DOI=10.1126/science.1203357;
RA Rhind N., Chen Z., Yassour M., Thompson D.A., Haas B.J., Habib N.,
RA Wapinski I., Roy S., Lin M.F., Heiman D.I., Young S.K., Furuya K., Guo Y.,
RA Pidoux A., Chen H.M., Robbertse B., Goldberg J.M., Aoki K., Bayne E.H.,
RA Berlin A.M., Desjardins C.A., Dobbs E., Dukaj L., Fan L., FitzGerald M.G.,
RA French C., Gujja S., Hansen K., Keifenheim D., Levin J.Z., Mosher R.A.,
RA Mueller C.A., Pfiffner J., Priest M., Russ C., Smialowska A., Swoboda P.,
RA Sykes S.M., Vaughn M., Vengrova S., Yoder R., Zeng Q., Allshire R.,
RA Baulcombe D., Birren B.W., Brown W., Ekwall K., Kellis M., Leatherwood J.,
RA Levin H., Margalit H., Martienssen R., Nieduszynski C.A., Spatafora J.W.,
RA Friedman N., Dalgaard J.Z., Baumann P., Niki H., Regev A., Nusbaum C.;
RT "Comparative functional genomics of the fission yeasts.";
RL Science 332:930-936(2011).
RN [3]
RP SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
RX PubMed=16823372; DOI=10.1038/nbt1222;
RA Matsuyama A., Arai R., Yashiroda Y., Shirai A., Kamata A., Sekido S.,
RA Kobayashi Y., Hashimoto A., Hamamoto M., Hiraoka Y., Horinouchi S.,
RA Yoshida M.;
RT "ORFeome cloning and global analysis of protein localization in the fission
RT yeast Schizosaccharomyces pombe.";
RL Nat. Biotechnol. 24:841-847(2006).
RN [4]
RP PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT THR-130; SER-131; SER-243 AND
RP SER-245, AND IDENTIFICATION BY MASS SPECTROMETRY.
RX PubMed=18257517; DOI=10.1021/pr7006335;
RA Wilson-Grady J.T., Villen J., Gygi S.P.;
RT "Phosphoproteome analysis of fission yeast.";
RL J. Proteome Res. 7:1088-1097(2008).
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00264,
CC ECO:0000269|PubMed:16823372}. Mitochondrion
CC {ECO:0000269|PubMed:16823372}.
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DR EMBL; CU329671; CAB39849.3; -; Genomic_DNA.
DR PIR; T40098; T40098.
DR RefSeq; NP_596216.3; NM_001022135.3.
DR AlphaFoldDB; Q9Y7K9; -.
DR SMR; Q9Y7K9; -.
DR BioGRID; 276988; 8.
DR STRING; 4896.SPBC2A9.07c.1; -.
DR iPTMnet; Q9Y7K9; -.
DR MaxQB; Q9Y7K9; -.
DR PaxDb; Q9Y7K9; -.
DR PRIDE; Q9Y7K9; -.
DR EnsemblFungi; SPBC2A9.07c.1; SPBC2A9.07c.1:pep; SPBC2A9.07c.
DR GeneID; 2540460; -.
DR KEGG; spo:SPBC2A9.07c; -.
DR PomBase; SPBC2A9.07c; -.
DR VEuPathDB; FungiDB:SPBC2A9.07c; -.
DR eggNOG; ENOG502S59M; Eukaryota.
DR HOGENOM; CLU_045993_3_1_1; -.
DR InParanoid; Q9Y7K9; -.
DR OMA; CGRSKIE; -.
DR PRO; PR:Q9Y7K9; -.
DR Proteomes; UP000002485; Chromosome II.
DR GO; GO:0005739; C:mitochondrion; HDA:PomBase.
DR GO; GO:0005634; C:nucleus; IDA:PomBase.
DR GO; GO:0003677; F:DNA binding; ISM:PomBase.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR GO; GO:2000134; P:negative regulation of G1/S transition of mitotic cell cycle; IMP:PomBase.
DR Gene3D; 3.30.1740.10; -; 1.
DR InterPro; IPR001510; Znf_PARP.
DR InterPro; IPR036957; Znf_PARP_sf.
DR Pfam; PF00645; zf-PARP; 1.
DR SMART; SM01336; zf-PARP; 1.
DR PROSITE; PS50064; PARP_ZN_FINGER_2; 1.
PE 1: Evidence at protein level;
KW DNA-binding; Metal-binding; Mitochondrion; Nucleus; Phosphoprotein;
KW Reference proteome; Zinc; Zinc-finger.
FT CHAIN 1..246
FT /note="PARP-type zinc finger-containing protein C2A9.07c"
FT /id="PRO_0000314104"
FT ZN_FING 8..99
FT /note="PARP-type; degenerate"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00264"
FT REGION 103..246
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 103..158
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 175..210
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT MOD_RES 130
FT /note="Phosphothreonine"
FT /evidence="ECO:0000250"
FT MOD_RES 131
FT /note="Phosphoserine"
FT /evidence="ECO:0000250"
FT MOD_RES 243
FT /note="Phosphoserine"
FT /evidence="ECO:0000250"
FT MOD_RES 245
FT /note="Phosphoserine"
FT /evidence="ECO:0000250"
SQ SEQUENCE 246 AA; 28172 MW; D67199F1B5B70CCB CRC64;
MAESGAGYRV ELAKTGRAEC KGTVCGRSKI GKGDLRFGTF VDVGKFQSWK WRHWGCVTER
VLRNVNKKFE GDIKNCLDGF NELNDPIVQE KILRAFEQGH VDEEDEERCR KMASDASEEK
DRKIEEGELT SEEEKEPIQD LRKSHKRKSV EKSSVPNKKH KAERKRSPSP KIEILEDDEE
IEDVASDKDE EEKPWSGDEE DDDELVVKDS EDETEGVSTI ASQRPRRSAR RKVDYAESGN
EYSDSD
