YGIQ_SALTI
ID YGIQ_SALTI Reviewed; 723 AA.
AC Q83SW5; Q8Z3P9;
DT 24-MAY-2004, integrated into UniProtKB/Swiss-Prot.
DT 01-JUN-2003, sequence version 1.
DT 03-AUG-2022, entry version 112.
DE RecName: Full=UPF0313 protein YgiQ {ECO:0000255|HAMAP-Rule:MF_01251};
GN Name=ygiQ {ECO:0000255|HAMAP-Rule:MF_01251};
GN OrderedLocusNames=STY3342, t3088;
OS Salmonella typhi.
OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Salmonella.
OX NCBI_TaxID=90370;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CT18;
RX PubMed=11677608; DOI=10.1038/35101607;
RA Parkhill J., Dougan G., James K.D., Thomson N.R., Pickard D., Wain J.,
RA Churcher C.M., Mungall K.L., Bentley S.D., Holden M.T.G., Sebaihia M.,
RA Baker S., Basham D., Brooks K., Chillingworth T., Connerton P., Cronin A.,
RA Davis P., Davies R.M., Dowd L., White N., Farrar J., Feltwell T.,
RA Hamlin N., Haque A., Hien T.T., Holroyd S., Jagels K., Krogh A.,
RA Larsen T.S., Leather S., Moule S., O'Gaora P., Parry C., Quail M.A.,
RA Rutherford K.M., Simmonds M., Skelton J., Stevens K., Whitehead S.,
RA Barrell B.G.;
RT "Complete genome sequence of a multiple drug resistant Salmonella enterica
RT serovar Typhi CT18.";
RL Nature 413:848-852(2001).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 700931 / Ty2;
RX PubMed=12644504; DOI=10.1128/jb.185.7.2330-2337.2003;
RA Deng W., Liou S.-R., Plunkett G. III, Mayhew G.F., Rose D.J., Burland V.,
RA Kodoyianni V., Schwartz D.C., Blattner F.R.;
RT "Comparative genomics of Salmonella enterica serovar Typhi strains Ty2 and
RT CT18.";
RL J. Bacteriol. 185:2330-2337(2003).
CC -!- COFACTOR:
CC Name=[4Fe-4S] cluster; Xref=ChEBI:CHEBI:49883;
CC Evidence={ECO:0000255|HAMAP-Rule:MF_01251};
CC Note=Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3
CC cysteines and an exchangeable S-adenosyl-L-methionine.
CC {ECO:0000255|HAMAP-Rule:MF_01251};
CC -!- SIMILARITY: Belongs to the UPF0313 family. {ECO:0000255|HAMAP-
CC Rule:MF_01251}.
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DR EMBL; AL513382; CAD02999.1; -; Genomic_DNA.
DR EMBL; AE014613; AAO70632.1; -; Genomic_DNA.
DR RefSeq; NP_457560.1; NC_003198.1.
DR RefSeq; WP_001274469.1; NZ_WSUR01000003.1.
DR AlphaFoldDB; Q83SW5; -.
DR STRING; 220341.16504245; -.
DR EnsemblBacteria; AAO70632; AAO70632; t3088.
DR KEGG; stt:t3088; -.
DR KEGG; sty:STY3342; -.
DR PATRIC; fig|220341.7.peg.3403; -.
DR eggNOG; COG1032; Bacteria.
DR HOGENOM; CLU_018288_2_0_6; -.
DR OMA; TCMYYTG; -.
DR Proteomes; UP000000541; Chromosome.
DR Proteomes; UP000002670; Chromosome.
DR GO; GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.
DR GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR GO; GO:0005506; F:iron ion binding; IEA:UniProtKB-UniRule.
DR Gene3D; 3.80.30.20; -; 1.
DR HAMAP; MF_01251; UPF0313; 1.
DR InterPro; IPR006638; Elp3/MiaB/NifB.
DR InterPro; IPR020612; Methylthiotransferase_CS.
DR InterPro; IPR007197; rSAM.
DR InterPro; IPR023404; rSAM_horseshoe.
DR InterPro; IPR022946; UPF0313.
DR InterPro; IPR024560; UPF0313_C.
DR InterPro; IPR013704; UPF0313_N.
DR PANTHER; PTHR32331; PTHR32331; 1.
DR Pfam; PF11842; DUF3362; 1.
DR Pfam; PF04055; Radical_SAM; 1.
DR Pfam; PF08497; Radical_SAM_N; 1.
DR SFLD; SFLDS00029; Radical_SAM; 1.
DR SFLD; SFLDG01069; UPF0313; 1.
DR SMART; SM00729; Elp3; 1.
DR TIGRFAMs; TIGR03904; SAM_YgiQ; 1.
DR PROSITE; PS51918; RADICAL_SAM; 1.
PE 3: Inferred from homology;
KW 4Fe-4S; Iron; Iron-sulfur; Metal-binding; S-adenosyl-L-methionine.
FT CHAIN 1..723
FT /note="UPF0313 protein YgiQ"
FT /id="PRO_0000076393"
FT DOMAIN 372..650
FT /note="Radical SAM core"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01266"
FT REGION 686..723
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT BINDING 386
FT /ligand="[4Fe-4S] cluster"
FT /ligand_id="ChEBI:CHEBI:49883"
FT /ligand_note="4Fe-4S-S-AdoMet"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01251"
FT BINDING 390
FT /ligand="[4Fe-4S] cluster"
FT /ligand_id="ChEBI:CHEBI:49883"
FT /ligand_note="4Fe-4S-S-AdoMet"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01251"
FT BINDING 393
FT /ligand="[4Fe-4S] cluster"
FT /ligand_id="ChEBI:CHEBI:49883"
FT /ligand_note="4Fe-4S-S-AdoMet"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01251"
FT CONFLICT 203
FT /note="E -> G (in Ref. 1; CAD02999)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 723 AA; 81925 MW; 0317AE64DCC967FE CRC64;
MSAISLIQPD RDLFSWPQYW AACFGPAPFL PMSREEMDQL GWDSCDIILV TGDAYVDHPS
FGMAICGRML EAQGFRVGII AQPDWNSKDD FMRLGKPNLF FGVTAGNMDS MINRYTADRK
LRHDDAYTPD NVAGKRPDRA TLVYTQRCKE AWKDVPVILG GIEASLRRTA HYDYWSDTVR
RSVLVDSKAD MLMFGNGERP LVEVAHRLAM GETIDQIRDV RNTAIMVKEA LPGWSGVDST
RLDTPGKIDP IPHPYGEDLP CADNKPVAPK KQEAKAITVQ PPRPKPWEKT YILLPSFEKV
KGDKVLYAHA SRILHHETNP GCARALMQKH GDRYVWINPP AIPLSTEEMD SVFALPYQRV
PHPAYGNARI PAYEMIRFSI NIMRGCFGGC SFCSITEHEG RIIQSRSEDS IINEIEAIRD
TVPGFTGVIS DLGGPTANMY MLRCKSPRAE QTCRRLSCVY PDICPHMDTD HTPTINLYRR
ARELKGIKKI LIASGVRYDI AVEDPRYIKE LASHHVGGYL KIAPEHTEEG PLSKMMKPGM
GSYDRFKELF DLYSKQAGKE QYLIPYFISA HPGTRDEDMV NLALWLKRHR FRLDQVQNFY
PSPLANSTTM YYTGKNPLGK IGYKSEDVVV PKGDRQRRLH KALLRYHDPA NWPLIRQALE
AMGKKHLIGG RRECLVPAPT IEEMREARRQ NRNTRPALTK HTPVEHQRQG LAANKKRGKG
AGR
