ID   YGIQ_SALTY              Reviewed;         723 AA.
AC   Q8ZM03;
DT   24-MAY-2004, integrated into UniProtKB/Swiss-Prot.
DT   01-MAR-2002, sequence version 1.
DT   03-AUG-2022, entry version 97.
DE   RecName: Full=UPF0313 protein YgiQ {ECO:0000255|HAMAP-Rule:MF_01251};
GN   Name=ygiQ {ECO:0000255|HAMAP-Rule:MF_01251}; OrderedLocusNames=STM3168;
OS   Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Salmonella.
OX   NCBI_TaxID=99287;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=LT2 / SGSC1412 / ATCC 700720;
RX   PubMed=11677609; DOI=10.1038/35101614;
RA   McClelland M., Sanderson K.E., Spieth J., Clifton S.W., Latreille P.,
RA   Courtney L., Porwollik S., Ali J., Dante M., Du F., Hou S., Layman D.,
RA   Leonard S., Nguyen C., Scott K., Holmes A., Grewal N., Mulvaney E.,
RA   Ryan E., Sun H., Florea L., Miller W., Stoneking T., Nhan M., Waterston R.,
RA   Wilson R.K.;
RT   "Complete genome sequence of Salmonella enterica serovar Typhimurium LT2.";
RL   Nature 413:852-856(2001).
CC   -!- COFACTOR:
CC       Name=[4Fe-4S] cluster; Xref=ChEBI:CHEBI:49883;
CC         Evidence={ECO:0000255|HAMAP-Rule:MF_01251};
CC       Note=Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3
CC       cysteines and an exchangeable S-adenosyl-L-methionine.
CC       {ECO:0000255|HAMAP-Rule:MF_01251};
CC   -!- SIMILARITY: Belongs to the UPF0313 family. {ECO:0000255|HAMAP-
CC       Rule:MF_01251}.
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DR   EMBL; AE006468; AAL22042.1; -; Genomic_DNA.
DR   RefSeq; NP_462083.1; NC_003197.2.
DR   RefSeq; WP_001274458.1; NC_003197.2.
DR   AlphaFoldDB; Q8ZM03; -.
DR   STRING; 99287.STM3168; -.
DR   PaxDb; Q8ZM03; -.
DR   EnsemblBacteria; AAL22042; AAL22042; STM3168.
DR   GeneID; 1254691; -.
DR   KEGG; stm:STM3168; -.
DR   PATRIC; fig|99287.12.peg.3359; -.
DR   HOGENOM; CLU_018288_2_0_6; -.
DR   OMA; TCMYYTG; -.
DR   PhylomeDB; Q8ZM03; -.
DR   BioCyc; SENT99287:STM3168-MON; -.
DR   Proteomes; UP000001014; Chromosome.
DR   GO; GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.
DR   GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR   GO; GO:0005506; F:iron ion binding; IEA:UniProtKB-UniRule.
DR   Gene3D; 3.80.30.20; -; 1.
DR   HAMAP; MF_01251; UPF0313; 1.
DR   InterPro; IPR006638; Elp3/MiaB/NifB.
DR   InterPro; IPR020612; Methylthiotransferase_CS.
DR   InterPro; IPR007197; rSAM.
DR   InterPro; IPR023404; rSAM_horseshoe.
DR   InterPro; IPR022946; UPF0313.
DR   InterPro; IPR024560; UPF0313_C.
DR   InterPro; IPR013704; UPF0313_N.
DR   PANTHER; PTHR32331; PTHR32331; 1.
DR   Pfam; PF11842; DUF3362; 1.
DR   Pfam; PF04055; Radical_SAM; 1.
DR   Pfam; PF08497; Radical_SAM_N; 1.
DR   SFLD; SFLDS00029; Radical_SAM; 1.
DR   SFLD; SFLDG01069; UPF0313; 1.
DR   SMART; SM00729; Elp3; 1.
DR   TIGRFAMs; TIGR03904; SAM_YgiQ; 1.
DR   PROSITE; PS51918; RADICAL_SAM; 1.
PE   3: Inferred from homology;
KW   4Fe-4S; Iron; Iron-sulfur; Metal-binding; Reference proteome;
KW   S-adenosyl-L-methionine.
FT   CHAIN           1..723
FT                   /note="UPF0313 protein YgiQ"
FT                   /id="PRO_0000076394"
FT   DOMAIN          372..650
FT                   /note="Radical SAM core"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01266"
FT   REGION          686..723
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   BINDING         386
FT                   /ligand="[4Fe-4S] cluster"
FT                   /ligand_id="ChEBI:CHEBI:49883"
FT                   /ligand_note="4Fe-4S-S-AdoMet"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01251"
FT   BINDING         390
FT                   /ligand="[4Fe-4S] cluster"
FT                   /ligand_id="ChEBI:CHEBI:49883"
FT                   /ligand_note="4Fe-4S-S-AdoMet"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01251"
FT   BINDING         393
FT                   /ligand="[4Fe-4S] cluster"
FT                   /ligand_id="ChEBI:CHEBI:49883"
FT                   /ligand_note="4Fe-4S-S-AdoMet"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01251"
SQ   SEQUENCE   723 AA;  81911 MW;  6854FA5B1C209949 CRC64;
     MSAISLIQPD RDLFSWPQYW AACFGPAPFL PMSRDEMDQL GWDSCDIILV TGDAYVDHPS
     FGMAICGRML EAQGFRVGII AQPDWNSKDD FMRLGKPNLF FGVTAGNMDS MINRYTADRK
     LRHDDAYTPD NVAGKRPDRA TLVYTQRCKE AWKDVPVILG GIEASLRRTA HYDYWSDTVR
     RSVLVDSKAD MLMFGNGERP LVEVAHRLAM GETIDQIRDV RNTAIMVKEA LPGWSGVDST
     RLDTPGKIDP IPHPYGEDLP CADNKPVAPK KQEAKAITVQ PPRPKPWEKT YILLPSFEKV
     KGDKVLYAHA SRILHHETNP GCARALMQKH GDRYVWINPP AIPLSTEEMD SVFALPYQRV
     PHPAYGNARI PAYEMIRFSI NIMRGCFGGC SFCSITEHEG RIIQSRSEDS IINEIEAIRD
     TVPGFTGVIS DLGGPTANMY MLRCKSPRAE QTCRRLSCVY PDICPHMDTD HTPTINLYRR
     ARELKGIKKI LIASGVRYDI AVEDPRYIKE LASHHVGGYL KIAPEHTEEG PLSKMMKPGM
     GSYDRFKELF DLYSKQAGKE QYLIPYFISA HPGTRDEDMV NLALWLKRHR FRLDQVQNFY
     PSPLANSTTM YYTGKNPLGK IGYKSEDVVV PKGDRQRRLH KALLRYHDPA NWPLIRQALE
     AMGKKHLIGG RRECLVPAPT IEEMREARRQ NRNTRPALTK HTPVEHQRQG LAANKKRGKG
     AGR