YGJI_ECOLI
ID YGJI_ECOLI Reviewed; 477 AA.
AC P42590; Q2M9C8; Q6BF49;
DT 01-NOV-1995, integrated into UniProtKB/Swiss-Prot.
DT 11-OCT-2004, sequence version 2.
DT 03-AUG-2022, entry version 148.
DE RecName: Full=Inner membrane transporter YgjI;
GN Name=ygjI; OrderedLocusNames=b3078, JW5512;
OS Escherichia coli (strain K12).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Escherichia.
OX NCBI_TaxID=83333;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=K12 / MG1655 / ATCC 47076;
RX PubMed=9278503; DOI=10.1126/science.277.5331.1453;
RA Blattner F.R., Plunkett G. III, Bloch C.A., Perna N.T., Burland V.,
RA Riley M., Collado-Vides J., Glasner J.D., Rode C.K., Mayhew G.F.,
RA Gregor J., Davis N.W., Kirkpatrick H.A., Goeden M.A., Rose D.J., Mau B.,
RA Shao Y.;
RT "The complete genome sequence of Escherichia coli K-12.";
RL Science 277:1453-1462(1997).
RN [2]
RP SEQUENCE REVISION TO 336-350.
RX PubMed=16397293; DOI=10.1093/nar/gkj405;
RA Riley M., Abe T., Arnaud M.B., Berlyn M.K.B., Blattner F.R.,
RA Chaudhuri R.R., Glasner J.D., Horiuchi T., Keseler I.M., Kosuge T.,
RA Mori H., Perna N.T., Plunkett G. III, Rudd K.E., Serres M.H., Thomas G.H.,
RA Thomson N.R., Wishart D., Wanner B.L.;
RT "Escherichia coli K-12: a cooperatively developed annotation snapshot
RT -- 2005.";
RL Nucleic Acids Res. 34:1-9(2006).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=K12 / W3110 / ATCC 27325 / DSM 5911;
RX PubMed=16738553; DOI=10.1038/msb4100049;
RA Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S.,
RA Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.;
RT "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655
RT and W3110.";
RL Mol. Syst. Biol. 2:E1-E5(2006).
RN [4]
RP TOPOLOGY [LARGE SCALE ANALYSIS].
RC STRAIN=K12 / MG1655 / ATCC 47076;
RX PubMed=15919996; DOI=10.1126/science.1109730;
RA Daley D.O., Rapp M., Granseth E., Melen K., Drew D., von Heijne G.;
RT "Global topology analysis of the Escherichia coli inner membrane
RT proteome.";
RL Science 308:1321-1323(2005).
CC -!- SUBCELLULAR LOCATION: Cell inner membrane; Multi-pass membrane protein.
CC -!- SIMILARITY: Belongs to the amino acid-polyamine-organocation (APC)
CC superfamily. {ECO:0000305}.
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DR EMBL; U18997; AAA57879.1; -; Genomic_DNA.
DR EMBL; U00096; AAT48165.1; -; Genomic_DNA.
DR EMBL; AP009048; BAE77128.1; -; Genomic_DNA.
DR PIR; C65096; C65096.
DR RefSeq; WP_001285432.1; NZ_LN832404.1.
DR RefSeq; YP_026200.1; NC_000913.3.
DR AlphaFoldDB; P42590; -.
DR SMR; P42590; -.
DR BioGRID; 4261469; 126.
DR DIP; DIP-12235N; -.
DR IntAct; P42590; 1.
DR STRING; 511145.b3078; -.
DR TCDB; 2.A.3.7.4; the amino acid-polyamine-organocation (apc) family.
DR PaxDb; P42590; -.
DR PRIDE; P42590; -.
DR EnsemblBacteria; AAT48165; AAT48165; b3078.
DR EnsemblBacteria; BAE77128; BAE77128; BAE77128.
DR GeneID; 947579; -.
DR KEGG; ecj:JW5512; -.
DR KEGG; eco:b3078; -.
DR PATRIC; fig|1411691.4.peg.3652; -.
DR EchoBASE; EB2579; -.
DR eggNOG; COG0531; Bacteria.
DR HOGENOM; CLU_020854_2_1_6; -.
DR InParanoid; P42590; -.
DR OMA; GITTWIF; -.
DR PhylomeDB; P42590; -.
DR BioCyc; EcoCyc:YGJI-MON; -.
DR PRO; PR:P42590; -.
DR Proteomes; UP000000318; Chromosome.
DR Proteomes; UP000000625; Chromosome.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005886; C:plasma membrane; IDA:EcoCyc.
DR GO; GO:0015171; F:amino acid transmembrane transporter activity; IBA:GO_Central.
DR GO; GO:0006865; P:amino acid transport; IBA:GO_Central.
DR InterPro; IPR002293; AA/rel_permease1.
DR Pfam; PF13520; AA_permease_2; 1.
PE 1: Evidence at protein level;
KW Cell inner membrane; Cell membrane; Membrane; Reference proteome;
KW Transmembrane; Transmembrane helix; Transport.
FT CHAIN 1..477
FT /note="Inner membrane transporter YgjI"
FT /id="PRO_0000213045"
FT TOPO_DOM 1..8
FT /note="Periplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 9..29
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 30..41
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 42..62
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 63..83
FT /note="Periplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 84..104
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 105..120
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 121..141
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 142..158
FT /note="Periplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 159..179
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 180..196
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 197..217
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 218..232
FT /note="Periplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 233..253
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 254..263
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 264..284
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 285..286
FT /note="Periplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 287..307
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 308..335
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 336..356
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 357..364
FT /note="Periplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 365..385
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 386..405
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 406..426
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 427..431
FT /note="Periplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 432..452
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 453..477
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT CONFLICT 336..350
FT /note="AAWIQFLIVIPLMII -> RSVDPVPDRHPADDY (in Ref. 1;
FT AAA57879)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 477 AA; 52147 MW; 4330E433B9EDD9DC CRC64;
MSDTKRNTIG KFGLLSLTFA AVYSFNNVIN NNIELGLASA PMFFLATIFY FIPFCLIIAE
FVSLNKNSEA GVYAWVKSSL GGRWAFITAY TYWFVNLFFF TSLLPRVIAY ASYAFLGYEY
IMTPVATTII SMVLFAFSTW VSTNGAKMLG PITSVTSTLM LLLTLSYILL AGTALVGGVQ
PADAITVDAM IPNFNWAFLG VTTWIFMAAG GAESVAVYVN DVKGGSKSFV KVIILAGIFI
GVLYSVSSVL INVFVSSKEL KFTGGSVQVF HGMAAYFGLP EALMNRFVGL VSFTAMFGSL
LMWTATPVKI FFSEIPEGIF GKKTVELNEN GVPARAAWIQ FLIVIPLMII PMLGSNTVQD
LMNTIINMTA AASMLPPLFI MLAYLNLRAK LDHLPRDFRM GSRRTGIIVV SMLIAIFAVG
FVASTFPTGA NILTIIFYNV GGIVIFLGFA WWKYSKYIKG LTAEERHIEA TPASNVD
