YGL4_YEAST
ID YGL4_YEAST Reviewed; 725 AA.
AC P53134; D6VU33;
DT 01-OCT-1996, integrated into UniProtKB/Swiss-Prot.
DT 01-OCT-1996, sequence version 1.
DT 03-AUG-2022, entry version 138.
DE RecName: Full=Putative oligopeptide transporter YGL114W;
GN OrderedLocusNames=YGL114W;
OS Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Saccharomycetaceae; Saccharomyces.
OX NCBI_TaxID=559292;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 204508 / S288c;
RX PubMed=9169869;
RA Tettelin H., Agostoni-Carbone M.L., Albermann K., Albers M., Arroyo J.,
RA Backes U., Barreiros T., Bertani I., Bjourson A.J., Brueckner M.,
RA Bruschi C.V., Carignani G., Castagnoli L., Cerdan E., Clemente M.L.,
RA Coblenz A., Coglievina M., Coissac E., Defoor E., Del Bino S., Delius H.,
RA Delneri D., de Wergifosse P., Dujon B., Durand P., Entian K.-D., Eraso P.,
RA Escribano V., Fabiani L., Fartmann B., Feroli F., Feuermann M.,
RA Frontali L., Garcia-Gonzalez M., Garcia-Saez M.I., Goffeau A.,
RA Guerreiro P., Hani J., Hansen M., Hebling U., Hernandez K., Heumann K.,
RA Hilger F., Hofmann B., Indge K.J., James C.M., Klima R., Koetter P.,
RA Kramer B., Kramer W., Lauquin G., Leuther H., Louis E.J., Maillier E.,
RA Marconi A., Martegani E., Mazon M.J., Mazzoni C., McReynolds A.D.K.,
RA Melchioretto P., Mewes H.-W., Minenkova O., Mueller-Auer S., Nawrocki A.,
RA Netter P., Neu R., Nombela C., Oliver S.G., Panzeri L., Paoluzi S.,
RA Plevani P., Portetelle D., Portillo F., Potier S., Purnelle B., Rieger M.,
RA Riles L., Rinaldi T., Robben J., Rodrigues-Pousada C.,
RA Rodriguez-Belmonte E., Rodriguez-Torres A.M., Rose M., Ruzzi M.,
RA Saliola M., Sanchez-Perez M., Schaefer B., Schaefer M., Scharfe M.,
RA Schmidheini T., Schreer A., Skala J., Souciet J.-L., Steensma H.Y.,
RA Talla E., Thierry A., Vandenbol M., van der Aart Q.J.M., Van Dyck L.,
RA Vanoni M., Verhasselt P., Voet M., Volckaert G., Wambutt R., Watson M.D.,
RA Weber N., Wedler E., Wedler H., Wipfli P., Wolf K., Wright L.F.,
RA Zaccaria P., Zimmermann M., Zollner A., Kleine K.;
RT "The nucleotide sequence of Saccharomyces cerevisiae chromosome VII.";
RL Nature 387:81-84(1997).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=ATCC 204508 / S288c;
RX PubMed=24374639; DOI=10.1534/g3.113.008995;
RA Engel S.R., Dietrich F.S., Fisk D.G., Binkley G., Balakrishnan R.,
RA Costanzo M.C., Dwight S.S., Hitz B.C., Karra K., Nash R.S., Weng S.,
RA Wong E.D., Lloyd P., Skrzypek M.S., Miyasato S.R., Simison M., Cherry J.M.;
RT "The reference genome sequence of Saccharomyces cerevisiae: Then and now.";
RL G3 (Bethesda) 4:389-398(2014).
RN [3]
RP IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RX PubMed=18407956; DOI=10.1074/mcp.m700468-mcp200;
RA Albuquerque C.P., Smolka M.B., Payne S.H., Bafna V., Eng J., Zhou H.;
RT "A multidimensional chromatography technology for in-depth phosphoproteome
RT analysis.";
RL Mol. Cell. Proteomics 7:1389-1396(2008).
RN [4]
RP IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RX PubMed=22814378; DOI=10.1073/pnas.1210303109;
RA Van Damme P., Lasa M., Polevoda B., Gazquez C., Elosegui-Artola A.,
RA Kim D.S., De Juan-Pardo E., Demeyer K., Hole K., Larrea E., Timmerman E.,
RA Prieto J., Arnesen T., Sherman F., Gevaert K., Aldabe R.;
RT "N-terminal acetylome analyses and functional insights of the N-terminal
RT acetyltransferase NatB.";
RL Proc. Natl. Acad. Sci. U.S.A. 109:12449-12454(2012).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Multi-pass membrane
CC protein {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the oligopeptide OPT transporter family.
CC {ECO:0000305}.
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DR EMBL; Z72636; CAA96822.1; -; Genomic_DNA.
DR EMBL; BK006941; DAA07994.1; -; Genomic_DNA.
DR PIR; S64124; S64124.
DR RefSeq; NP_011401.1; NM_001180979.1.
DR AlphaFoldDB; P53134; -.
DR SMR; P53134; -.
DR BioGRID; 33137; 173.
DR DIP; DIP-7780N; -.
DR STRING; 4932.YGL114W; -.
DR TCDB; 2.A.67.2.7; the oligopeptide transporter (opt) family.
DR iPTMnet; P53134; -.
DR MaxQB; P53134; -.
DR PaxDb; P53134; -.
DR PRIDE; P53134; -.
DR EnsemblFungi; YGL114W_mRNA; YGL114W; YGL114W.
DR GeneID; 852764; -.
DR KEGG; sce:YGL114W; -.
DR SGD; S000003082; YGL114W.
DR VEuPathDB; FungiDB:YGL114W; -.
DR eggNOG; ENOG502QQ2H; Eukaryota.
DR HOGENOM; CLU_010539_2_0_1; -.
DR InParanoid; P53134; -.
DR OMA; FGMSDIV; -.
DR BioCyc; YEAST:G3O-30612-MON; -.
DR ChiTaRS; YGL114W; yeast.
DR PRO; PR:P53134; -.
DR Proteomes; UP000002311; Chromosome VII.
DR RNAct; P53134; protein.
DR GO; GO:0000329; C:fungal-type vacuole membrane; HDA:SGD.
DR GO; GO:0005887; C:integral component of plasma membrane; ISS:SGD.
DR GO; GO:0016020; C:membrane; IBA:GO_Central.
DR GO; GO:0035673; F:oligopeptide transmembrane transporter activity; ISS:SGD.
DR GO; GO:0006857; P:oligopeptide transport; ISS:SGD.
DR GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR InterPro; IPR004813; OPT.
DR InterPro; IPR045035; YSL-like.
DR PANTHER; PTHR31645; PTHR31645; 1.
DR Pfam; PF03169; OPT; 1.
DR TIGRFAMs; TIGR00728; OPT_sfam; 1.
PE 1: Evidence at protein level;
KW Membrane; Peptide transport; Protein transport; Reference proteome;
KW Transmembrane; Transmembrane helix; Transport.
FT CHAIN 1..725
FT /note="Putative oligopeptide transporter YGL114W"
FT /id="PRO_0000213789"
FT TRANSMEM 28..48
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 134..154
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 254..274
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 353..373
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 449..469
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 472..492
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 564..584
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 644..664
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 697..717
FT /note="Helical"
FT /evidence="ECO:0000255"
SQ SEQUENCE 725 AA; 80009 MW; 23FCAF5988758F1B CRC64;
MPQSTPSQEV QRVPWDNKPA LKQITLRATI AGIAIGSLVL TSNFQFGLQT GWVSMMSLPS
ALLACAFFKN IWPLIFPNDR PFSDVENVYV QSMAVAVGTG PLAFGFVGVI PAIEKFLTND
ESGGLREQGQ SFTFRELLIW STALAFFGIF FAVPLRKQVI VREKLPFPSG SATATLISVL
NGTEILQEVS KSELLEMRQR RLNECPEVLQ PNRDPEEADY LMNSSHSELG DYTATSQDGS
SILSTGSENY RANIIILLKT FVVSSLYTMV SYFVPVIRSI PVFGKYLSNN YLWNFQPSPA
YIGQGIIMGL PTVSYMLIGC FLGWGVLAPL ARYKRWVPPD ADVHDWEEGV QGWILWSSLS
IMVADSVVAF IVVTVKSIVK FILIDDKAAL LNNIIDDTFQ SMLLEEERAI NSSRRNTYVD
GRQDTVRLVS RDNEIEVDSK HLVRYTTVIS GCLVSSIICI VSIIYLFGIQ VIPLYAIITA
LILALFLSIL GIRALGETDL NPVSGIGKIS QLIFAFIIPR DRPGSVLMNV VSGGIAEASA
QQAGDLMQDL KTGHLLGASP RAQFCAQLIG ACWSIILSSF MYLCYNKVYS IPSEQFRIPT
AVVWIDCARL VTGKGLPDKA LECSMILGVI FAVLSLIRNT YRDYGYGWIL YIPSGVAVGV
GIFNSPSFTI ARFIGGWASH FWLKNHRGDL NAKTKMIVFS SGLVLGEGIF SVINMLFICL
NVPHY
