ID   YGSA_SCHPO              Reviewed;        1944 AA.
AC   O94387;
DT   23-SEP-2008, integrated into UniProtKB/Swiss-Prot.
DT   01-MAY-1999, sequence version 1.
DT   03-AUG-2022, entry version 114.
DE   RecName: Full=Uncharacterized ATP-dependent helicase C29A10.10c;
DE            EC=3.6.4.-;
GN   ORFNames=SPBC29A10.10c;
OS   Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina;
OC   Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae;
OC   Schizosaccharomyces.
OX   NCBI_TaxID=284812;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=972 / ATCC 24843;
RX   PubMed=11859360; DOI=10.1038/nature724;
RA   Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A.,
RA   Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S.,
RA   Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M.,
RA   Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S.,
RA   Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S.,
RA   Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D.,
RA   Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P.,
RA   Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K.,
RA   O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M.,
RA   Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N.,
RA   Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A.,
RA   Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R.,
RA   Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M.,
RA   Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A.,
RA   Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A.,
RA   Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H.,
RA   Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S.,
RA   Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C.,
RA   Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A.,
RA   Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M.,
RA   del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S.,
RA   Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R.,
RA   Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G.,
RA   Nurse P.;
RT   "The genome sequence of Schizosaccharomyces pombe.";
RL   Nature 415:871-880(2002).
RN   [2]
RP   SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
RX   PubMed=16823372; DOI=10.1038/nbt1222;
RA   Matsuyama A., Arai R., Yashiroda Y., Shirai A., Kamata A., Sekido S.,
RA   Kobayashi Y., Hashimoto A., Hamamoto M., Hiraoka Y., Horinouchi S.,
RA   Yoshida M.;
RT   "ORFeome cloning and global analysis of protein localization in the fission
RT   yeast Schizosaccharomyces pombe.";
RL   Nat. Biotechnol. 24:841-847(2006).
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000269|PubMed:16823372}.
CC   -!- SIMILARITY: Belongs to the DNA2/NAM7 helicase family. {ECO:0000305}.
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DR   EMBL; CU329671; CAA22438.1; -; Genomic_DNA.
DR   PIR; T40065; T40065.
DR   RefSeq; NP_596055.1; NM_001021966.2.
DR   AlphaFoldDB; O94387; -.
DR   SMR; O94387; -.
DR   BioGRID; 277051; 38.
DR   STRING; 4896.SPBC29A10.10c.1; -.
DR   iPTMnet; O94387; -.
DR   MaxQB; O94387; -.
DR   PaxDb; O94387; -.
DR   PRIDE; O94387; -.
DR   EnsemblFungi; SPBC29A10.10c.1; SPBC29A10.10c.1:pep; SPBC29A10.10c.
DR   GeneID; 2540523; -.
DR   KEGG; spo:SPBC29A10.10c; -.
DR   PomBase; SPBC29A10.10c; -.
DR   VEuPathDB; FungiDB:SPBC29A10.10c; -.
DR   eggNOG; KOG1801; Eukaryota.
DR   HOGENOM; CLU_000459_2_0_1; -.
DR   InParanoid; O94387; -.
DR   OMA; YGCSKCI; -.
DR   PhylomeDB; O94387; -.
DR   PRO; PR:O94387; -.
DR   Proteomes; UP000002485; Chromosome II.
DR   GO; GO:0000785; C:chromatin; IDA:PomBase.
DR   GO; GO:0016604; C:nuclear body; IBA:GO_Central.
DR   GO; GO:0030874; C:nucleolar chromatin; IDA:PomBase.
DR   GO; GO:0005634; C:nucleus; HDA:PomBase.
DR   GO; GO:0035861; C:site of double-strand break; IDA:PomBase.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR   GO; GO:0003723; F:RNA binding; IBA:GO_Central.
DR   GO; GO:0003724; F:RNA helicase activity; ISO:PomBase.
DR   GO; GO:0001147; F:transcription termination site sequence-specific DNA binding; IBA:GO_Central.
DR   GO; GO:0031123; P:RNA 3'-end processing; ISO:PomBase.
DR   GO; GO:0006369; P:termination of RNA polymerase II transcription; IBA:GO_Central.
DR   GO; GO:0006399; P:tRNA metabolic process; NAS:PomBase.
DR   CDD; cd18808; SF1_C_Upf1; 1.
DR   Gene3D; 3.40.50.300; -; 2.
DR   InterPro; IPR016024; ARM-type_fold.
DR   InterPro; IPR045055; DNA2/NAM7-like.
DR   InterPro; IPR041679; DNA2/NAM7-like_C.
DR   InterPro; IPR041677; DNA2/NAM7_AAA_11.
DR   InterPro; IPR024481; Helicase_Sen1_N.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR026121; Sen1.
DR   PANTHER; PTHR10887; PTHR10887; 2.
DR   PANTHER; PTHR10887:SF487; PTHR10887:SF487; 2.
DR   Pfam; PF13086; AAA_11; 1.
DR   Pfam; PF13087; AAA_12; 1.
DR   Pfam; PF12726; SEN1_N; 1.
DR   SUPFAM; SSF48371; SSF48371; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
PE   3: Inferred from homology;
KW   ATP-binding; Helicase; Hydrolase; Nucleotide-binding; Nucleus;
KW   Reference proteome.
FT   CHAIN           1..1944
FT                   /note="Uncharacterized ATP-dependent helicase C29A10.10c"
FT                   /id="PRO_0000350747"
FT   REGION          908..999
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          1824..1944
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1824..1856
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1869..1911
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   BINDING         1293..1300
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   1944 AA;  222211 MW;  12B005A934BEE11C CRC64;
     MENDEAFDRL IRKIQENQKH PSFEGSNKVL HLALSYLNTN RQNPHWVCDP KLQVAVRECL
     FLFSFQNDNE YLVWFKKHLN ERLQLCPKCI VKYHQSLDDF KSLCLNIFHF DPNTLEIVME
     KIYSWDIFRL QEVLKTVPKI DTSSASKPIL CAFYEILYSP RILHNKEIFP LFRNRFLESG
     FLRLSKNLVP GVISLLFSRD DELRRWACSI LSDVKTISDN EFKILEGPLL QEIRSLDQKK
     ENENEMQIFL KGLSLLLKHV DHLYFRGLTG KNFNVADFIL SGLQSDHTNL CPSFLVCLHS
     LLYCYGRNFW TPEISPSEVI DKIFNGNAYK RWTEENTSNF SNDQKAENPF EWATSLLKTI
     SIIDEVELIN KILINYTMQY KKELEVGFKN VQLLQSLADI FSVLFSEYFM IFPHSDQSLQ
     NKVFELHSTL AIKFDELFRL LNLENEESVE WRLIKKVFEY RLNLDLYILK QFYCHYLDRN
     RKPPLNIKSV SESFKNFWVY LQNVFREEKF FMVRIVFRAC STVCLIDKLP PKKVDIPFKS
     DFENALNGFV ATFSEMLIQT QCWHLSAQTQ LVSNPLTFRG IFSLVFSPIL EISTGSISII
     KSISLSDSVV DTIGELLRSQ FSNTLNSSCY VLLQWLKVRN FGGAKHIVYF NKLIINTIFD
     SVDGLTSKDA TFAKQVEKKE SLKNFWESLW KFFTHFFIVL PTWPVHDKDN LVDLMRDTLD
     FCDMLINIFE EVNGFIFGLS DNDIKIVSAN DKGSALAMCI ADSLVTVSYW LKLTDSSLLT
     SVVKVICKML KICKKLECPI SQNVIDIIHR ASITSDEQTI LTFTEREDLF ISLTPYLSED
     VLNHSPFNDT NTLETKLQSD DRGLLSKDQT IGIAKKLPES NISTSNHFLL PPKAISASKA
     INRNAQKSQN LNFLKSKQET TQRIRESAKV PRTSAGNHLS EKLNSDNHIP KALQKLDSAD
     PIRKPSLLHT SKSYSNPDDK NTSTSDEDTS ESEEESSNGL FSLAREANSH ASKSLPQRRQ
     IQFLDFDSLK TKNVVHPTQL RRNTQQSAQL ARLRLNPDVQ EFYKVILGWN PLADSFSASN
     VEMQCVQAKF TYNDSNAYEK VFKPMLFHEC WAQVKSAVEE KQYPPIDLIL NTRSTVDNFV
     DIYFTSCSPT EVSFLSDTDI CLLSKSQSSG DTNNPKSFQL CKIQSISRKK ESLELCLRMN
     IESIDLQEYA PNIRFTAQKL FNATTSLREF AALKSLRHLP LSQRILDANV TRLPSNFTDD
     KKQKIMKSYG VNEPQAYAIY ASSVNDGFTL IQGPPGTGKT KTILGMIGAV LTSSSQGLQF
     NVPGQTRKTS KNKILICAPS NAAIDEILLR IKAGVYDHEG IKFFPKVIRV GFGDSISVHA
     KEFTLEEQMI KQMELTNLKK DQEANNSSDT RKKYDSIIKK RDSLREDLEK FRSTGKNSSI
     LEAQLREITK QKNMLEQSLD DMRERQRSTN RNLDVLKKQI QNQLLQEADI VCATLSASGH
     ELLLNAGLTF RTVIIDEAAQ AVELSSIIPL KYGCESCVMV GDPNQLPPTV LSKTSAKFGY
     SQSLYVRMFK QHNESACLLS IQYRMNPEIS RFPSKFFYNS KLLDGPNMSA VTSRPWHEDP
     QLGIYRFFNV HGTEAFSNSK SLYNVEEASF ILLLYERLIQ CYLNIDFEGK IGVVTPYRSQ
     VQQLRSQFQR KYGSIIFKHL DIHTVDGFQG QEKDIIIFSC VRSSMSGGIG FLQDLRRLNV
     ALTRAKSSLY IVGNSKPLMQ EDIFYSLIED AKTRGVWRDL SANQFKNSKS ISNVSTHLAS
     NNLNLASRDT PIKSPSVGIC EEKQEAHKVK KRHNIDSANL SRGTERDEDI PNKRAKNKVS
     TDQTAADNKV TKPRLDESSS SKQDVLNKID ESEIEQASSK KPGYVEKNKD KGHMKKSKKP
     KSKLALAAMA HGFAPPKVEH FKRK