YGVA_SCHPO
ID YGVA_SCHPO Reviewed; 963 AA.
AC O43024;
DT 10-JUN-2008, integrated into UniProtKB/Swiss-Prot.
DT 01-JUN-1998, sequence version 1.
DT 03-AUG-2022, entry version 107.
DE RecName: Full=CUE domain-containing protein C354.10;
GN ORFNames=SPBC354.10;
OS Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina;
OC Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae;
OC Schizosaccharomyces.
OX NCBI_TaxID=284812;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=972 / ATCC 24843;
RX PubMed=11859360; DOI=10.1038/nature724;
RA Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A.,
RA Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S.,
RA Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M.,
RA Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S.,
RA Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S.,
RA Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D.,
RA Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P.,
RA Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K.,
RA O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M.,
RA Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N.,
RA Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A.,
RA Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R.,
RA Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M.,
RA Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A.,
RA Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A.,
RA Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H.,
RA Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S.,
RA Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C.,
RA Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A.,
RA Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M.,
RA del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S.,
RA Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R.,
RA Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G.,
RA Nurse P.;
RT "The genome sequence of Schizosaccharomyces pombe.";
RL Nature 415:871-880(2002).
RN [2]
RP SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
RX PubMed=16823372; DOI=10.1038/nbt1222;
RA Matsuyama A., Arai R., Yashiroda Y., Shirai A., Kamata A., Sekido S.,
RA Kobayashi Y., Hashimoto A., Hamamoto M., Hiraoka Y., Horinouchi S.,
RA Yoshida M.;
RT "ORFeome cloning and global analysis of protein localization in the fission
RT yeast Schizosaccharomyces pombe.";
RL Nat. Biotechnol. 24:841-847(2006).
RN [3]
RP PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT THR-474 AND SER-476, AND
RP IDENTIFICATION BY MASS SPECTROMETRY.
RX PubMed=18257517; DOI=10.1021/pr7006335;
RA Wilson-Grady J.T., Villen J., Gygi S.P.;
RT "Phosphoproteome analysis of fission yeast.";
RL J. Proteome Res. 7:1088-1097(2008).
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000269|PubMed:16823372}.
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DR EMBL; CU329671; CAA17810.1; -; Genomic_DNA.
DR PIR; T40290; T40290.
DR RefSeq; NP_595234.1; NM_001021140.2.
DR AlphaFoldDB; O43024; -.
DR SMR; O43024; -.
DR BioGRID; 277446; 97.
DR STRING; 4896.SPBC354.10.1; -.
DR iPTMnet; O43024; -.
DR MaxQB; O43024; -.
DR PaxDb; O43024; -.
DR PRIDE; O43024; -.
DR EnsemblFungi; SPBC354.10.1; SPBC354.10.1:pep; SPBC354.10.
DR GeneID; 2540930; -.
DR KEGG; spo:SPBC354.10; -.
DR PomBase; SPBC354.10; -.
DR VEuPathDB; FungiDB:SPBC354.10; -.
DR eggNOG; ENOG502S359; Eukaryota.
DR HOGENOM; CLU_323936_0_0_1; -.
DR InParanoid; O43024; -.
DR OMA; TANTSGM; -.
DR PRO; PR:O43024; -.
DR Proteomes; UP000002485; Chromosome II.
DR GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR GO; GO:0005829; C:cytosol; HDA:PomBase.
DR GO; GO:0005634; C:nucleus; ISO:PomBase.
DR GO; GO:0043130; F:ubiquitin binding; IEA:InterPro.
DR GO; GO:0000723; P:telomere maintenance; ISO:PomBase.
DR GO; GO:0006283; P:transcription-coupled nucleotide-excision repair; ISO:PomBase.
DR GO; GO:0006511; P:ubiquitin-dependent protein catabolic process; ISO:PomBase.
DR CDD; cd14368; CUE_DEF1_like; 1.
DR InterPro; IPR003892; CUE.
DR InterPro; IPR041803; DEF1_CUE.
DR Pfam; PF02845; CUE; 1.
DR PROSITE; PS51140; CUE; 1.
PE 1: Evidence at protein level;
KW Cytoplasm; Phosphoprotein; Reference proteome; Ubl conjugation pathway.
FT CHAIN 1..963
FT /note="CUE domain-containing protein C354.10"
FT /id="PRO_0000339335"
FT DOMAIN 77..120
FT /note="CUE"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00468"
FT REGION 1..72
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 119..417
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 444..517
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..18
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 19..44
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 54..70
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 138..158
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 201..276
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 312..368
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 380..415
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 456..470
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 476..500
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT MOD_RES 474
FT /note="Phosphothreonine"
FT /evidence="ECO:0000269|PubMed:18257517"
FT MOD_RES 476
FT /note="Phosphoserine"
FT /evidence="ECO:0000269|PubMed:18257517"
SQ SEQUENCE 963 AA; 100134 MW; 42F9D5A82A994EFF CRC64;
MSENKKFRPK KVGNTEQVSE KQHTDTALNI SQDNKTSSSS AKRGAKGRRG TKGKSGPANS
SQTSNIEGSN ALELEFDRDS QLSVLQELFP SWTIDDLSFA LEEADRDLEL TILHITEGHA
SKWGEVKKKP IPKTKSKPTS HAPVSDNVSS TFRNATRKSK KPSASKDTSR GVRKSKAGAP
SDPSSVHAPS SLEKPAGTGD LPSSEISTKA PASTTVSSSV DPGTINEDSS MKDHTTSNEQ
ASVLTSANTA ASTNTNGTAG GTSASAKSTS AADQAVASSK PIKKAWASVA KSKKKVTPAP
APAPESEPSK PSIAPSQPSK TNVSAAYEKP AELSSSSVPF PHKSQDSATP ANVETTPSTA
TSAPKKSTAP FAINAVKPAP GLSNISSASL PKPSFAKQAA VGSQSSTTSM TTARLLSDRF
PVVMPVANTA AIPEKVQVRF GSLTLGGEDK KSTKSSSDNI AQSGPRSSYF PKKTVSPKPE
AKKEASKVAE STKIPKKQHT SAYESRAPQS KVPENLKESH VNETPYRGLH DVNLPASGNA
SSVSAIPPQV SAQTTIPAAS TSATSGPVVG KQSAGYGGIY SPATHGISPQ PYAGASLIPP
STGAAFNNET ASSNAGETTA LPYSSRFMNP VENRSANSPF DNFQHIDHST ELGYASNTSQ
QYQQTSHPAY TTMSPIEYGQ AAPAAHYYNE RNQYSQYDNV AGSASNTPDV HSVMHNKVAS
SNATSLPAAG TATPSPVVSQ QQPQPYAFPP MYPIPYVSYG YGTMPYNNNK FGQPQQGYMS
QSGFNDFPPI FGGHSNVYNR QQPGNVSGMS GTQTSNPINN ATANTSGMTE KAAGHRDSVI
GNGGVTGANS MSSTLGGLSS MSGMGRAAPG MFMGNVGSFE NLSANAASPY GLPPQQTPLT
NAATQQTTSF QSNANKVNNA NSQPAGFPFN SGASTNAGSN GLGGYNAYNQ SFINRPGGWY
GNA
