ID   YGX1_SCHPO              Reviewed;         374 AA.
AC   O94280;
DT   04-NOV-2008, integrated into UniProtKB/Swiss-Prot.
DT   01-MAY-1999, sequence version 1.
DT   03-AUG-2022, entry version 107.
DE   RecName: Full=UPF0674 endoplasmic reticulum membrane protein C2G5.01;
GN   ORFNames=SPBC2G5.01;
OS   Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina;
OC   Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae;
OC   Schizosaccharomyces.
OX   NCBI_TaxID=284812;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=972 / ATCC 24843;
RX   PubMed=11859360; DOI=10.1038/nature724;
RA   Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A.,
RA   Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S.,
RA   Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M.,
RA   Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S.,
RA   Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S.,
RA   Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D.,
RA   Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P.,
RA   Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K.,
RA   O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M.,
RA   Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N.,
RA   Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A.,
RA   Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R.,
RA   Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M.,
RA   Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A.,
RA   Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A.,
RA   Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H.,
RA   Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S.,
RA   Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C.,
RA   Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A.,
RA   Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M.,
RA   del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S.,
RA   Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R.,
RA   Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G.,
RA   Nurse P.;
RT   "The genome sequence of Schizosaccharomyces pombe.";
RL   Nature 415:871-880(2002).
CC   -!- SUBCELLULAR LOCATION: Endoplasmic reticulum membrane {ECO:0000305};
CC       Single-pass membrane protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the UPF0674 family. {ECO:0000305}.
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DR   EMBL; CU329671; CAA21877.1; -; Genomic_DNA.
DR   PIR; T40158; T40158.
DR   RefSeq; NP_596062.1; NM_001021973.2.
DR   AlphaFoldDB; O94280; -.
DR   BioGRID; 276889; 25.
DR   STRING; 4896.SPBC2G5.01.1; -.
DR   iPTMnet; O94280; -.
DR   MaxQB; O94280; -.
DR   PaxDb; O94280; -.
DR   PRIDE; O94280; -.
DR   EnsemblFungi; SPBC2G5.01.1; SPBC2G5.01.1:pep; SPBC2G5.01.
DR   GeneID; 2540360; -.
DR   KEGG; spo:SPBC2G5.01; -.
DR   PomBase; SPBC2G5.01; -.
DR   VEuPathDB; FungiDB:SPBC2G5.01; -.
DR   eggNOG; KOG2357; Eukaryota.
DR   HOGENOM; CLU_727922_0_0_1; -.
DR   InParanoid; O94280; -.
DR   OMA; PPIDQKV; -.
DR   PhylomeDB; O94280; -.
DR   PRO; PR:O94280; -.
DR   Proteomes; UP000002485; Chromosome II.
DR   GO; GO:0005783; C:endoplasmic reticulum; HDA:PomBase.
DR   GO; GO:0160005; C:PAT complex; TAS:PomBase.
DR   GO; GO:0005509; F:calcium ion binding; IBA:GO_Central.
DR   GO; GO:0044183; F:protein folding chaperone; ISM:PomBase.
DR   GO; GO:0032469; P:endoplasmic reticulum calcium ion homeostasis; IEA:InterPro.
DR   GO; GO:0045048; P:protein insertion into ER membrane; ISS:PomBase.
DR   InterPro; IPR012879; CCDC47.
DR   PANTHER; PTHR12883; PTHR12883; 1.
DR   Pfam; PF07946; DUF1682; 1.
PE   3: Inferred from homology;
KW   Endoplasmic reticulum; Glycoprotein; Membrane; Reference proteome;
KW   Transmembrane; Transmembrane helix.
FT   CHAIN           1..374
FT                   /note="UPF0674 endoplasmic reticulum membrane protein
FT                   C2G5.01"
FT                   /id="PRO_0000353797"
FT   TRANSMEM        49..68
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   REGION          335..374
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        339..361
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   CARBOHYD        287
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   374 AA;  43098 MW;  B72DDE7AA4AC9935 CRC64;
     MINKKLLFLV FALAKGVLAD EEDEYEEDYN MNPELENPGM FKHVDWRDFR LEFVILACFF
     LYVFSFITQK KKNQKIASRW YGSLQSSFRQ QFAQYGPGPN SSPIIYDSPT EFSSYLTGRL
     NVKNVYTTLQ LFPRQDLLAY SLNQIVEILL GNVMSSVLPV ADRFQFDLTL ADQNLKAERF
     VFAIVHKDCM RILREIRYDL SFTRISSSPY LPETHVLMSE NNECSQAIFE IPEFMSSINE
     CIENLEYFIV TDQPSVPPAT EKDYVTKPRI EASIRIKKIT SLSGLSNATG SALFNSLLLV
     ADSCPKFQWR PEVSKKLTSA RKLAFEQVVH ASAAKAAKKK VKSSGDISKL SESDQKKRME
     RERQRKMRRR AKKM