ID   YH05_SCHPO              Reviewed;         997 AA.
AC   O74325;
DT   13-NOV-2007, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1998, sequence version 1.
DT   03-AUG-2022, entry version 116.
DE   RecName: Full=PDZ domain-containing protein C1685.05;
GN   ORFNames=SPBC1685.05;
OS   Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina;
OC   Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae;
OC   Schizosaccharomyces.
OX   NCBI_TaxID=284812;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=972 / ATCC 24843;
RX   PubMed=11859360; DOI=10.1038/nature724;
RA   Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A.,
RA   Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S.,
RA   Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M.,
RA   Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S.,
RA   Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S.,
RA   Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D.,
RA   Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P.,
RA   Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K.,
RA   O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M.,
RA   Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N.,
RA   Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A.,
RA   Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R.,
RA   Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M.,
RA   Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A.,
RA   Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A.,
RA   Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H.,
RA   Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S.,
RA   Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C.,
RA   Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A.,
RA   Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M.,
RA   del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S.,
RA   Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R.,
RA   Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G.,
RA   Nurse P.;
RT   "The genome sequence of Schizosaccharomyces pombe.";
RL   Nature 415:871-880(2002).
RN   [2]
RP   SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
RX   PubMed=16823372; DOI=10.1038/nbt1222;
RA   Matsuyama A., Arai R., Yashiroda Y., Shirai A., Kamata A., Sekido S.,
RA   Kobayashi Y., Hashimoto A., Hamamoto M., Hiraoka Y., Horinouchi S.,
RA   Yoshida M.;
RT   "ORFeome cloning and global analysis of protein localization in the fission
RT   yeast Schizosaccharomyces pombe.";
RL   Nat. Biotechnol. 24:841-847(2006).
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000269|PubMed:16823372}.
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DR   EMBL; CU329671; CAA20053.1; -; Genomic_DNA.
DR   PIR; T39521; T39521.
DR   RefSeq; NP_595209.1; NM_001021116.2.
DR   AlphaFoldDB; O74325; -.
DR   SMR; O74325; -.
DR   BioGRID; 276480; 12.
DR   STRING; 4896.SPBC1685.05.1; -.
DR   iPTMnet; O74325; -.
DR   MaxQB; O74325; -.
DR   PaxDb; O74325; -.
DR   PRIDE; O74325; -.
DR   EnsemblFungi; SPBC1685.05.1; SPBC1685.05.1:pep; SPBC1685.05.
DR   GeneID; 2539936; -.
DR   KEGG; spo:SPBC1685.05; -.
DR   PomBase; SPBC1685.05; -.
DR   VEuPathDB; FungiDB:SPBC1685.05; -.
DR   eggNOG; KOG1421; Eukaryota.
DR   HOGENOM; CLU_003212_0_0_1; -.
DR   InParanoid; O74325; -.
DR   OMA; PRHRLIN; -.
DR   PhylomeDB; O74325; -.
DR   PRO; PR:O74325; -.
DR   Proteomes; UP000002485; Chromosome II.
DR   GO; GO:0005829; C:cytosol; HDA:PomBase.
DR   GO; GO:0004252; F:serine-type endopeptidase activity; ISO:PomBase.
DR   GO; GO:0051603; P:proteolysis involved in protein catabolic process; ISO:PomBase.
DR   Gene3D; 2.30.42.10; -; 1.
DR   InterPro; IPR025926; PDZ-like_dom.
DR   InterPro; IPR036034; PDZ_sf.
DR   InterPro; IPR009003; Peptidase_S1_PA.
DR   Pfam; PF12812; PDZ_1; 1.
DR   SUPFAM; SSF50156; SSF50156; 2.
DR   SUPFAM; SSF50494; SSF50494; 2.
PE   4: Predicted;
KW   Cytoplasm; Reference proteome.
FT   CHAIN           1..997
FT                   /note="PDZ domain-containing protein C1685.05"
FT                   /id="PRO_0000310847"
FT   DOMAIN          78..268
FT                   /note="Peptidase S1"
FT   DOMAIN          870..955
FT                   /note="PDZ"
FT   REGION          507..534
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   997 AA;  111294 MW;  D32D7E3CCAE877A0 CRC64;
     MTPVSSDYRP NHIFLPKFRP DKITSECNTP QQQNVIAEGL YNVSEPFPIR NTDEERYLDT
     KEIHHTWDNT IKNVVRSIVS IKGSALRSFD TESAGSFCAT GFVVNKTLGL ILSNRHVVSP
     GPISARASFI NYEEIDIYPI YRDPVHDFGF FRYDPSSIRF HDVTEISLSP ESAKVGIDIR
     IIGNDAGEKL SILSSTLARL DRPAPNYGID NYNDFNTFYY QAASGTSGGS SGSPVLDISG
     AAVALNSGGS NSSASSFYLP LDRVVRALRC IENNTPITRG TLLTEFLHWS YDELSRIGLP
     REFEYDCRTR VPSSTGLLVV SRVLRNSEVS KALEPGDILI AFKTDSHKST YIVDFVSLFE
     VLDEMVGKTI ELHVYRPKRG FLTFQLTVQD LHNVTPSRFL EVGGAVLHDL SYQLARSYQF
     SLNSGTYVAS SGMLNWSSGT RDFLVTRLAN KPTPTLDAFI DVLVQLTDNA RVPMHFRVLG
     KYEEEFTIVT VDRHFFLASI FSRNDEKGTW DRQSLPPPQP SISRRPSVIP RPQEGSKSME
     AIQNALVLVH CRMPYSINGF SSTKLYSGTG VIVSVVPPLI VVDRSVIPVD ICDIRLTFQS
     MSAMGHLTFL DNRIAVVSCD YLPSNSVQLN FVADFLRTGD ECTLAALDED LQLLTKKTTV
     RSVSVVETER SSPPRFRYVN CEVISLMDSL ASTGGLVFRE VGDDREIVAL WISVVHQDVG
     GKDYTTKYGL SMSYILPVLE RLKLPPSARA QHVPTTAGVE WSHITLAGAS TLGLSQTRSS
     EFYMKSRENG TIPRPLYVIS HLRPLLHKTS LGVGDILLEV NGKMITRLSD LHEFETESEI
     KAVILRDGIE MEITIPLYPE YPTFSSRAIC WMGAIIHPTH SSVFEQVEPD VDLPGPEGVY
     VGSILYGSPA LNMLRAAHWI VAVDGHDINT FDDFYHMLLE KPTDTFVQVK QMNRRGATSI
     VSVRPDPLFW PTCIIERDSN GRWCTKHLQR KTKEVCS