YH41A_YEAST
ID YH41A_YEAST Reviewed; 413 AA.
AC Q6Q5P6; D3DKQ6;
DT 06-MAR-2007, integrated into UniProtKB/Swiss-Prot.
DT 05-JUL-2004, sequence version 1.
DT 25-MAY-2022, entry version 110.
DE RecName: Full=Transposon Ty4-H Gag polyprotein;
DE Short=TY4A;
DE Short=Transposon Ty4 protein A;
GN Name=TY4A-H; Synonyms=YHLWTy4-1 GAG; OrderedLocusNames=YHL009W-A;
GN ORFNames=YHL008W-B;
OS Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Saccharomycetaceae; Saccharomyces.
OX NCBI_TaxID=559292;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 204508 / S288c;
RX PubMed=8091229; DOI=10.1126/science.8091229;
RA Johnston M., Andrews S., Brinkman R., Cooper J., Ding H., Dover J., Du Z.,
RA Favello A., Fulton L., Gattung S., Geisel C., Kirsten J., Kucaba T.,
RA Hillier L.W., Jier M., Johnston L., Langston Y., Latreille P., Louis E.J.,
RA Macri C., Mardis E., Menezes S., Mouser L., Nhan M., Rifkin L., Riles L.,
RA St Peter H., Trevaskis E., Vaughan K., Vignati D., Wilcox L., Wohldman P.,
RA Waterston R., Wilson R., Vaudin M.;
RT "Complete nucleotide sequence of Saccharomyces cerevisiae chromosome
RT VIII.";
RL Science 265:2077-2082(1994).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=ATCC 204508 / S288c;
RX PubMed=24374639; DOI=10.1534/g3.113.008995;
RA Engel S.R., Dietrich F.S., Fisk D.G., Binkley G., Balakrishnan R.,
RA Costanzo M.C., Dwight S.S., Hitz B.C., Karra K., Nash R.S., Weng S.,
RA Wong E.D., Lloyd P., Skrzypek M.S., Miyasato S.R., Simison M., Cherry J.M.;
RT "The reference genome sequence of Saccharomyces cerevisiae: Then and now.";
RL G3 (Bethesda) 4:389-398(2014).
RN [3]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=ATCC 204508 / S288c;
RX PubMed=17322287; DOI=10.1101/gr.6037607;
RA Hu Y., Rolfs A., Bhullar B., Murthy T.V.S., Zhu C., Berger M.F.,
RA Camargo A.A., Kelley F., McCarron S., Jepson D., Richardson A., Raphael J.,
RA Moreira D., Taycher E., Zuo D., Mohr S., Kane M.F., Williamson J.,
RA Simpson A.J.G., Bulyk M.L., Harlow E., Marsischky G., Kolodner R.D.,
RA LaBaer J.;
RT "Approaching a complete repository of sequence-verified protein-encoding
RT clones for Saccharomyces cerevisiae.";
RL Genome Res. 17:536-543(2007).
RN [4]
RP NOMENCLATURE.
RX PubMed=9582191; DOI=10.1101/gr.8.5.464;
RA Kim J.M., Vanguri S., Boeke J.D., Gabriel A., Voytas D.F.;
RT "Transposable elements and genome organization: a comprehensive survey of
RT retrotransposons revealed by the complete Saccharomyces cerevisiae genome
RT sequence.";
RL Genome Res. 8:464-478(1998).
RN [5]
RP REVIEW.
RX PubMed=16093660; DOI=10.1159/000084940;
RA Lesage P., Todeschini A.L.;
RT "Happy together: the life and times of Ty retrotransposons and their
RT hosts.";
RL Cytogenet. Genome Res. 110:70-90(2005).
CC -!- FUNCTION: Capsid protein (CA) is the structural component of the virus-
CC like particle (VLP), forming the shell that encapsulates the
CC retrotransposons dimeric RNA genome. {ECO:0000250}.
CC -!- ALTERNATIVE PRODUCTS:
CC Event=Ribosomal frameshifting; Named isoforms=2;
CC Comment=The Gag-Pol polyprotein is generated by a +1 ribosomal
CC frameshift.;
CC Name=Transposon Ty4-H Gag polyprotein;
CC IsoId=Q6Q5P6-1; Sequence=Displayed;
CC Name=Transposon Ty4-H Gag-Pol polyprotein;
CC IsoId=P0C2J7-1; Sequence=External;
CC -!- MISCELLANEOUS: Retrotransposons are mobile genetic entities that are
CC able to replicate via an RNA intermediate and a reverse transcription
CC step. In contrast to retroviruses, retrotransposons are non-infectious,
CC lack an envelope and remain intracellular. Ty4 retrotransposons belong
CC to the copia elements (pseudoviridae).
CC -!- MISCELLANEOUS: [Isoform Transposon Ty4-H Gag polyprotein]: Produced by
CC conventional translation.
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DR EMBL; U11581; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AY557839; AAS56165.1; -; Genomic_DNA.
DR EMBL; BK006934; DAA06679.1; -; Genomic_DNA.
DR PIR; S52610; S52610.
DR RefSeq; NP_058134.1; NM_001184403.1. [Q6Q5P6-1]
DR AlphaFoldDB; Q6Q5P6; -.
DR SMR; Q6Q5P6; -.
DR BioGRID; 36416; 15.
DR PaxDb; Q6Q5P6; -.
DR TopDownProteomics; Q6Q5P6-1; -. [Q6Q5P6-1]
DR GeneID; 856379; -.
DR KEGG; sce:YHL009W-A; -.
DR SGD; S000007371; YHL009W-A.
DR VEuPathDB; FungiDB:YHL009W-A; -.
DR eggNOG; KOG0017; Eukaryota.
DR HOGENOM; CLU_065017_0_0_1; -.
DR InParanoid; Q6Q5P6; -.
DR Proteomes; UP000002311; Chromosome VIII.
DR RNAct; Q6Q5P6; protein.
DR GO; GO:0000943; C:retrotransposon nucleocapsid; ISS:SGD.
DR GO; GO:0003723; F:RNA binding; ISS:SGD.
DR GO; GO:0032197; P:transposition, RNA-mediated; ISS:SGD.
PE 3: Inferred from homology;
KW Coiled coil; Reference proteome; Ribosomal frameshifting;
KW Transposable element.
FT CHAIN 1..413
FT /note="Transposon Ty4-H Gag polyprotein"
FT /id="PRO_0000279381"
FT REGION 380..413
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 39..115
FT /evidence="ECO:0000255"
SQ SEQUENCE 413 AA; 48214 MW; FB55118BEC987195 CRC64;
MATPVRDETR NVIDDNISAR IQSKVKTNDT VRQTPSSLRK VSIKDEQVKQ YQRNLNRFKT
ILNGLKAEEE KLSETDDIQM LAEKLLKLGE TIDKVENRIV DLVEKIQLLE TNENNNILHE
HIDATGTYYL FDTLTSTNKR FYPKDCVFDY RTNNVENIPI LLNNFKKFIK KYQFDDVFEN
DIIEIDPREN EILCKIIKEG LGESLDIMNT NTTDIFRIID GLKNKYRSLH GRDVRIRAWE
KVLVDTTCRN SALLMNKLQK LVLMEKWIFS KCCQDCPNLK DYLQEAIMGT LHESLRNSVK
QRLYNIPHNV GINHEEFLIN TVIETVIDLS PIADDQIENS CMYCKSVFHC SINCKKKPNR
ELRPDSTNFS KTYYLQGAQR QQQLKSSAKR TKVLEQDTKK VKQSVQQQKT GNY
