YH7H_SCHPO
ID YH7H_SCHPO Reviewed; 560 AA.
AC O60131;
DT 13-NOV-2007, integrated into UniProtKB/Swiss-Prot.
DT 01-AUG-1998, sequence version 1.
DT 25-MAY-2022, entry version 112.
DE RecName: Full=Uncharacterized transcriptional regulatory protein C16G5.17;
GN ORFNames=SPBC16G5.17;
OS Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina;
OC Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae;
OC Schizosaccharomyces.
OX NCBI_TaxID=284812;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=972 / ATCC 24843;
RX PubMed=11859360; DOI=10.1038/nature724;
RA Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A.,
RA Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S.,
RA Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M.,
RA Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S.,
RA Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S.,
RA Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D.,
RA Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P.,
RA Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K.,
RA O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M.,
RA Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N.,
RA Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A.,
RA Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R.,
RA Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M.,
RA Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A.,
RA Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A.,
RA Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H.,
RA Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S.,
RA Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C.,
RA Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A.,
RA Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M.,
RA del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S.,
RA Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R.,
RA Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G.,
RA Nurse P.;
RT "The genome sequence of Schizosaccharomyces pombe.";
RL Nature 415:871-880(2002).
RN [2]
RP SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
RX PubMed=16823372; DOI=10.1038/nbt1222;
RA Matsuyama A., Arai R., Yashiroda Y., Shirai A., Kamata A., Sekido S.,
RA Kobayashi Y., Hashimoto A., Hamamoto M., Hiraoka Y., Horinouchi S.,
RA Yoshida M.;
RT "ORFeome cloning and global analysis of protein localization in the fission
RT yeast Schizosaccharomyces pombe.";
RL Nat. Biotechnol. 24:841-847(2006).
CC -!- SUBCELLULAR LOCATION: Nucleus membrane {ECO:0000255|PROSITE-
CC ProRule:PRU00227, ECO:0000269|PubMed:16823372}; Single-pass membrane
CC protein {ECO:0000269|PubMed:16823372}.
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DR EMBL; CU329671; CAA19036.1; -; Genomic_DNA.
DR PIR; T39609; T39609.
DR RefSeq; NP_596766.1; NM_001023786.2.
DR AlphaFoldDB; O60131; -.
DR SMR; O60131; -.
DR BioGRID; 276452; 16.
DR STRING; 4896.SPBC16G5.17.1; -.
DR PaxDb; O60131; -.
DR EnsemblFungi; SPBC16G5.17.1; SPBC16G5.17.1:pep; SPBC16G5.17.
DR GeneID; 2539906; -.
DR KEGG; spo:SPBC16G5.17; -.
DR PomBase; SPBC16G5.17; -.
DR VEuPathDB; FungiDB:SPBC16G5.17; -.
DR HOGENOM; CLU_037354_0_0_1; -.
DR InParanoid; O60131; -.
DR OMA; IFEEYGW; -.
DR PRO; PR:O60131; -.
DR Proteomes; UP000002485; Chromosome II.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0031965; C:nuclear membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005634; C:nucleus; HDA:PomBase.
DR GO; GO:0000981; F:DNA-binding transcription factor activity, RNA polymerase II-specific; NAS:PomBase.
DR GO; GO:0000978; F:RNA polymerase II cis-regulatory region sequence-specific DNA binding; ISM:PomBase.
DR GO; GO:0008270; F:zinc ion binding; ISM:PomBase.
DR GO; GO:0006357; P:regulation of transcription by RNA polymerase II; NAS:PomBase.
DR CDD; cd00067; GAL4; 1.
DR Gene3D; 4.10.240.10; -; 1.
DR InterPro; IPR001138; Zn2-C6_fun-type_DNA-bd.
DR InterPro; IPR036864; Zn2-C6_fun-type_DNA-bd_sf.
DR Pfam; PF00172; Zn_clus; 1.
DR SMART; SM00066; GAL4; 1.
DR SUPFAM; SSF57701; SSF57701; 1.
DR PROSITE; PS00463; ZN2_CY6_FUNGAL_1; 1.
DR PROSITE; PS50048; ZN2_CY6_FUNGAL_2; 1.
PE 3: Inferred from homology;
KW DNA-binding; Membrane; Metal-binding; Nucleus; Reference proteome;
KW Transcription; Transcription regulation; Transmembrane;
KW Transmembrane helix; Zinc.
FT CHAIN 1..560
FT /note="Uncharacterized transcriptional regulatory protein
FT C16G5.17"
FT /id="PRO_0000310384"
FT TRANSMEM 182..202
FT /note="Helical"
FT /evidence="ECO:0000255"
FT DNA_BIND 18..44
FT /note="Zn(2)-C6 fungal-type"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00227"
FT REGION 60..80
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 62..80
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 560 AA; 65114 MW; 74FDCC56AFED843B CRC64;
MVGKSKNRAH KNIRARSCLR CRRRKVKCDR QYPCSRCKES EESCTYGVNE QAVQLLEEPL
SRPITRETDS SAHQETRTRL EENNLPKTQK FGFVDWKTIL KSSAEFQGIV QRDPESRLRE
ALETDPKLKK RLECILETIP PWDVCESLLK VYANTFNVTN YILDFEQADK LLSDLKNSNH
VFATSIILIV TAIAVALSLE SFPSNIERYF SAVNHSAIEL SDALNSKIDD FLNEEVIFRL
WRNIDRIRLH AIRAQLCMRN QFRSMNTDLC YAIHYACFVN PIFQNTDTEY EANMEVWLSI
CEIDALECVL RSCQPWVQHD IYGKLLSQRK MGSDVISYEF HSLLGQLLTC GLEIYKAIHT
STVNEFVNSI QFYESQLSLV LMEIESKFSN IDGSDIHFRY LFLKTVFWTV RKNLYQGFIT
VSRTLVPNYP DIVQKLGQTS IQLSRLISNS MDCFEKYGWL KAMLILVTHT FLIIHVCSER
GYDVPKDFWN VTASVQATLE EKKYPGIVWE RIHYVLNIYT TINSVEPELS EDHGDLDDQN
LFQVFTDIFD FNFNFPLPNL
