ID   YHA8_SCHPO              Reviewed;         552 AA.
AC   Q7Z9I0;
DT   05-MAY-2009, integrated into UniProtKB/Swiss-Prot.
DT   05-OCT-2016, sequence version 2.
DT   25-MAY-2022, entry version 111.
DE   RecName: Full=Uncharacterized MFS-type transporter SPBC409.08;
GN   ORFNames=SPBC409.08;
OS   Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina;
OC   Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae;
OC   Schizosaccharomyces.
OX   NCBI_TaxID=284812;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=972 / ATCC 24843;
RX   PubMed=11859360; DOI=10.1038/nature724;
RA   Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A.,
RA   Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S.,
RA   Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M.,
RA   Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S.,
RA   Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S.,
RA   Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D.,
RA   Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P.,
RA   Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K.,
RA   O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M.,
RA   Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N.,
RA   Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A.,
RA   Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R.,
RA   Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M.,
RA   Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A.,
RA   Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A.,
RA   Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H.,
RA   Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S.,
RA   Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C.,
RA   Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A.,
RA   Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M.,
RA   del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S.,
RA   Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R.,
RA   Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G.,
RA   Nurse P.;
RT   "The genome sequence of Schizosaccharomyces pombe.";
RL   Nature 415:871-880(2002).
RN   [2]
RP   GENE MODEL REVISION.
RX   PubMed=24929437; DOI=10.1038/nsmb.2843;
RA   Duncan C.D., Mata J.;
RT   "The translational landscape of fission-yeast meiosis and sporulation.";
RL   Nat. Struct. Mol. Biol. 21:641-647(2014).
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000255}; Multi-pass membrane
CC       protein {ECO:0000255}.
CC   -!- SIMILARITY: Belongs to the major facilitator superfamily.
CC       {ECO:0000255}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=CAB52610.2; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR   EMBL; CU329671; CAB52610.2; ALT_SEQ; Genomic_DNA.
DR   RefSeq; NP_595458.1; NM_001021368.2.
DR   AlphaFoldDB; Q7Z9I0; -.
DR   BioGRID; 277530; 7.
DR   STRING; 4896.SPBC409.08.1; -.
DR   TCDB; 2.A.1.2.108; the major facilitator superfamily (mfs).
DR   PaxDb; Q7Z9I0; -.
DR   EnsemblFungi; SPBC409.08.1; SPBC409.08.1:pep; SPBC409.08.
DR   GeneID; 2541015; -.
DR   KEGG; spo:SPBC409.08; -.
DR   PomBase; SPBC409.08; -.
DR   eggNOG; KOG0255; Eukaryota.
DR   HOGENOM; CLU_008455_11_5_1; -.
DR   InParanoid; Q7Z9I0; -.
DR   PRO; PR:Q7Z9I0; -.
DR   Proteomes; UP000002485; Chromosome II.
DR   GO; GO:0000329; C:fungal-type vacuole membrane; IBA:GO_Central.
DR   GO; GO:0005887; C:integral component of plasma membrane; IBA:GO_Central.
DR   GO; GO:0005886; C:plasma membrane; ISM:PomBase.
DR   GO; GO:0000297; F:spermine transmembrane transporter activity; ISO:PomBase.
DR   GO; GO:0022857; F:transmembrane transporter activity; IBA:GO_Central.
DR   GO; GO:1903710; P:spermine transmembrane transport; ISO:PomBase.
DR   GO; GO:0000296; P:spermine transport; IBA:GO_Central.
DR   GO; GO:0055085; P:transmembrane transport; IBA:GO_Central.
DR   Gene3D; 1.20.1250.20; -; 1.
DR   InterPro; IPR011701; MFS.
DR   InterPro; IPR020846; MFS_dom.
DR   InterPro; IPR036259; MFS_trans_sf.
DR   InterPro; IPR005829; Sugar_transporter_CS.
DR   Pfam; PF07690; MFS_1; 1.
DR   SUPFAM; SSF103473; SSF103473; 1.
DR   PROSITE; PS50850; MFS; 1.
PE   3: Inferred from homology;
KW   Membrane; Reference proteome; Transmembrane; Transmembrane helix;
KW   Transport.
FT   CHAIN           1..552
FT                   /note="Uncharacterized MFS-type transporter SPBC409.08"
FT                   /id="PRO_0000372711"
FT   TRANSMEM        116..136
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        158..178
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        181..201
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        203..223
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        238..258
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        271..291
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        345..365
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        383..403
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        424..444
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        450..470
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        484..506
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        519..539
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   REGION          1..59
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1..16
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        17..59
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   552 AA;  61213 MW;  346B8B90D0E47847 CRC64;
     MPLEKTNTHD STATVEDQEA TDNPMHLTQS RMLDLAGNPN RTTSRQSETL FPNGVDLNYP
     FTTTRGPPDV AEYNLETAEG VYRDPTINEG EEELVTWELN DPENPHNWSR LWKWYITIVN
     SLLVVCSAFG SSVIAGDLED VSRDLKVGPE VANLSCSLMV VGFGIGPLVI SPLSEMIGRR
     IVYLVTLMIY IVLQIPCALA PNIACLLIVR FFCGCFGCTP LTLAGGVISD VWETRERGLA
     IAFFAAGPYA GPTLGPLVGG WIGVGTGDFR WIFWVNMIYM FVMYLTLLPV PETYAPVLLR
     WRAQRIRKET GRQVFTAQEK QMLSFKEIVQ VNLTRPLTLL LTEPILVCIS GYIALIYALL
     YGYFFAYPNV FVKGKGYNEG ITGLMFIPIL VGVVGALSTT PFLEKQYMAK LDANNGKSVP
     EWRLVGMCIA SPFIPTGLLI FAWTSFPRLI WIGPAFSGAP FGYGMVLFYF SANNYLIDVY
     QNYCASALAA KTMVRSAGGA AFPLFIDYMM DGMTRQWAFF LLGMVAVAAI PIPFTFYLFG
     DKIRARSKAA IV