ID   YHAI_ECOLI              Reviewed;         118 AA.
AC   P64592; P42622; Q2M9A2;
DT   11-OCT-2004, integrated into UniProtKB/Swiss-Prot.
DT   11-OCT-2004, sequence version 1.
DT   03-AUG-2022, entry version 105.
DE   RecName: Full=Inner membrane protein YhaI;
GN   Name=yhaI; OrderedLocusNames=b3104, JW3075;
OS   Escherichia coli (strain K12).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Escherichia.
OX   NCBI_TaxID=83333;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=K12 / MG1655 / ATCC 47076;
RX   PubMed=9278503; DOI=10.1126/science.277.5331.1453;
RA   Blattner F.R., Plunkett G. III, Bloch C.A., Perna N.T., Burland V.,
RA   Riley M., Collado-Vides J., Glasner J.D., Rode C.K., Mayhew G.F.,
RA   Gregor J., Davis N.W., Kirkpatrick H.A., Goeden M.A., Rose D.J., Mau B.,
RA   Shao Y.;
RT   "The complete genome sequence of Escherichia coli K-12.";
RL   Science 277:1453-1462(1997).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=K12 / W3110 / ATCC 27325 / DSM 5911;
RX   PubMed=16738553; DOI=10.1038/msb4100049;
RA   Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S.,
RA   Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.;
RT   "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655
RT   and W3110.";
RL   Mol. Syst. Biol. 2:E1-E5(2006).
RN   [3]
RP   TOPOLOGY [LARGE SCALE ANALYSIS].
RC   STRAIN=K12 / MG1655 / ATCC 47076;
RX   PubMed=15919996; DOI=10.1126/science.1109730;
RA   Daley D.O., Rapp M., Granseth E., Melen K., Drew D., von Heijne G.;
RT   "Global topology analysis of the Escherichia coli inner membrane
RT   proteome.";
RL   Science 308:1321-1323(2005).
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane; Multi-pass membrane protein.
CC   -!- SIMILARITY: To E.coli YhaH. {ECO:0000305}.
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DR   EMBL; U18997; AAA57908.1; -; Genomic_DNA.
DR   EMBL; U00096; AAC76139.1; -; Genomic_DNA.
DR   EMBL; AP009048; BAE77154.1; -; Genomic_DNA.
DR   PIR; E65099; E65099.
DR   RefSeq; NP_417575.1; NC_000913.3.
DR   RefSeq; WP_001198807.1; NZ_LN832404.1.
DR   AlphaFoldDB; P64592; -.
DR   BioGRID; 4259258; 7.
DR   STRING; 511145.b3104; -.
DR   TCDB; 9.B.124.1.1; the duf805 or pf05656 (duf805) family.
DR   PaxDb; P64592; -.
DR   PRIDE; P64592; -.
DR   DNASU; 947612; -.
DR   EnsemblBacteria; AAC76139; AAC76139; b3104.
DR   EnsemblBacteria; BAE77154; BAE77154; BAE77154.
DR   GeneID; 947612; -.
DR   KEGG; ecj:JW3075; -.
DR   KEGG; eco:b3104; -.
DR   PATRIC; fig|1411691.4.peg.3624; -.
DR   EchoBASE; EB2604; -.
DR   eggNOG; COG3152; Bacteria.
DR   HOGENOM; CLU_093674_4_1_6; -.
DR   InParanoid; P64592; -.
DR   OMA; WFIWLGF; -.
DR   PhylomeDB; P64592; -.
DR   BioCyc; EcoCyc:G7618-MON; -.
DR   PRO; PR:P64592; -.
DR   Proteomes; UP000000318; Chromosome.
DR   Proteomes; UP000000625; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IDA:EcoCyc.
DR   InterPro; IPR008523; DUF805.
DR   PANTHER; PTHR34980; PTHR34980; 1.
DR   Pfam; PF05656; DUF805; 1.
PE   1: Evidence at protein level;
KW   Cell inner membrane; Cell membrane; Membrane; Reference proteome;
KW   Transmembrane; Transmembrane helix.
FT   CHAIN           1..118
FT                   /note="Inner membrane protein YhaI"
FT                   /id="PRO_0000169445"
FT   TOPO_DOM        1..25
FT                   /note="Periplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        26..46
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        47
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        48..68
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        69..77
FT                   /note="Periplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        78..98
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        99..118
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   118 AA;  13456 MW;  2FA008344024B1D9 CRC64;
     MQWYLSVLKN YVGFSGRARR KEYWMFTLIN AIVGAIINVI QLILGLELPY LSMLYLLATF
     LPVLALAIRR LHDTDRSGAW ALLFFVPFIG WLVLLVFFCT EGTSGSNRYG NDPKFGSN