ID   YHAJ_ECOLI              Reviewed;         298 AA.
AC   P67660; P42623; Q2M9A1;
DT   11-OCT-2004, integrated into UniProtKB/Swiss-Prot.
DT   11-OCT-2004, sequence version 1.
DT   03-AUG-2022, entry version 120.
DE   RecName: Full=Probable HTH-type transcriptional regulator YhaJ;
GN   Name=yhaJ; OrderedLocusNames=b3105, JW3076;
OS   Escherichia coli (strain K12).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Escherichia.
OX   NCBI_TaxID=83333;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=K12 / MG1655 / ATCC 47076;
RX   PubMed=9278503; DOI=10.1126/science.277.5331.1453;
RA   Blattner F.R., Plunkett G. III, Bloch C.A., Perna N.T., Burland V.,
RA   Riley M., Collado-Vides J., Glasner J.D., Rode C.K., Mayhew G.F.,
RA   Gregor J., Davis N.W., Kirkpatrick H.A., Goeden M.A., Rose D.J., Mau B.,
RA   Shao Y.;
RT   "The complete genome sequence of Escherichia coli K-12.";
RL   Science 277:1453-1462(1997).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=K12 / W3110 / ATCC 27325 / DSM 5911;
RX   PubMed=16738553; DOI=10.1038/msb4100049;
RA   Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S.,
RA   Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.;
RT   "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655
RT   and W3110.";
RL   Mol. Syst. Biol. 2:E1-E5(2006).
CC   -!- FUNCTION: Positive regulator, may be partially responsible for
CC       expression of neighboring gene dlsT (yhaO) (By similarity).
CC       {ECO:0000250|UniProtKB:P67661}.
CC   -!- SIMILARITY: Belongs to the LysR transcriptional regulatory family.
CC       {ECO:0000305}.
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DR   EMBL; U18997; AAA57909.1; -; Genomic_DNA.
DR   EMBL; U00096; AAC76140.1; -; Genomic_DNA.
DR   EMBL; AP009048; BAE77155.1; -; Genomic_DNA.
DR   PIR; F65099; F65099.
DR   RefSeq; NP_417576.1; NC_000913.3.
DR   RefSeq; WP_001041009.1; NZ_LN832404.1.
DR   AlphaFoldDB; P67660; -.
DR   SMR; P67660; -.
DR   BioGRID; 4259259; 11.
DR   BioGRID; 851937; 3.
DR   DIP; DIP-35869N; -.
DR   IntAct; P67660; 13.
DR   STRING; 511145.b3105; -.
DR   jPOST; P67660; -.
DR   PaxDb; P67660; -.
DR   PRIDE; P67660; -.
DR   DNASU; 947621; -.
DR   EnsemblBacteria; AAC76140; AAC76140; b3105.
DR   EnsemblBacteria; BAE77155; BAE77155; BAE77155.
DR   GeneID; 947621; -.
DR   KEGG; ecj:JW3076; -.
DR   KEGG; eco:b3105; -.
DR   PATRIC; fig|511145.12.peg.3201; -.
DR   EchoBASE; EB2605; -.
DR   eggNOG; COG0583; Bacteria.
DR   HOGENOM; CLU_039613_35_1_6; -.
DR   InParanoid; P67660; -.
DR   OMA; YVHKRSG; -.
DR   PhylomeDB; P67660; -.
DR   BioCyc; EcoCyc:G7619-MON; -.
DR   PRO; PR:P67660; -.
DR   Proteomes; UP000000318; Chromosome.
DR   Proteomes; UP000000625; Chromosome.
DR   GO; GO:0001216; F:DNA-binding transcription activator activity; IDA:EcoCyc.
DR   GO; GO:0000976; F:transcription cis-regulatory region binding; IBA:GO_Central.
DR   GO; GO:2000144; P:positive regulation of DNA-templated transcription, initiation; IDA:EcoCyc.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IBA:GO_Central.
DR   Gene3D; 1.10.10.10; -; 1.
DR   InterPro; IPR005119; LysR_subst-bd.
DR   InterPro; IPR000847; Tscrpt_reg_HTH_LysR.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   Pfam; PF00126; HTH_1; 1.
DR   Pfam; PF03466; LysR_substrate; 1.
DR   SUPFAM; SSF46785; SSF46785; 1.
DR   PROSITE; PS50931; HTH_LYSR; 1.
PE   3: Inferred from homology;
KW   Activator; DNA-binding; Reference proteome; Transcription;
KW   Transcription regulation.
FT   CHAIN           1..298
FT                   /note="Probable HTH-type transcriptional regulator YhaJ"
FT                   /id="PRO_0000105796"
FT   DOMAIN          7..64
FT                   /note="HTH lysR-type"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00253"
FT   DNA_BIND        24..43
FT                   /note="H-T-H motif"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00253"
SQ   SEQUENCE   298 AA;  33256 MW;  4B6062F8ED8A3293 CRC64;
     MAKERALTLE ALRVMDAIDR RGSFAAAADE LGRVPSALSY TMQKLEEELD VVLFDRSGHR
     TKFTNVGRML LERGRVLLEA ADKLTTDAEA LARGWETHLT IVTEALVPTP AFFPLIDKLA
     AKANTQLAII TEVLAGAWER LEQGRADIVI APDMHFRSSS EINSRKLYTL MNVYVAAPDH
     PIHQEPEPLS EVTRVKYRGI AVADTARERP VLTVQLLDKQ PRLTVSTIED KRQALLAGLG
     VATMPYPMVE KDIAEGRLRV VSPESTSEID IIMAWRRDSM GEAKSWCLRE IPKLFNGK