ID   YHAM_GEOKA              Reviewed;         325 AA.
AC   Q5L299;
DT   02-AUG-2005, integrated into UniProtKB/Swiss-Prot.
DT   01-FEB-2005, sequence version 1.
DT   25-MAY-2022, entry version 89.
DE   RecName: Full=3'-5' exoribonuclease YhaM {ECO:0000255|HAMAP-Rule:MF_01427};
DE            EC=3.1.-.- {ECO:0000255|HAMAP-Rule:MF_01427};
GN   Name=yhaM {ECO:0000255|HAMAP-Rule:MF_01427}; OrderedLocusNames=GK0646;
OS   Geobacillus kaustophilus (strain HTA426).
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Bacillaceae; Geobacillus;
OC   Geobacillus thermoleovorans group.
OX   NCBI_TaxID=235909;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=HTA426;
RX   PubMed=15576355; DOI=10.1093/nar/gkh970;
RA   Takami H., Takaki Y., Chee G.-J., Nishi S., Shimamura S., Suzuki H.,
RA   Matsui S., Uchiyama I.;
RT   "Thermoadaptation trait revealed by the genome sequence of thermophilic
RT   Geobacillus kaustophilus.";
RL   Nucleic Acids Res. 32:6292-6303(2004).
CC   -!- FUNCTION: Shows a 3'-5' exoribonuclease activity. {ECO:0000255|HAMAP-
CC       Rule:MF_01427}.
CC   -!- SIMILARITY: Belongs to the YhaM family. {ECO:0000255|HAMAP-
CC       Rule:MF_01427}.
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DR   EMBL; BA000043; BAD74931.1; -; Genomic_DNA.
DR   RefSeq; WP_011230150.1; NC_006510.1.
DR   AlphaFoldDB; Q5L299; -.
DR   SMR; Q5L299; -.
DR   STRING; 235909.GK0646; -.
DR   EnsemblBacteria; BAD74931; BAD74931; GK0646.
DR   KEGG; gka:GK0646; -.
DR   eggNOG; COG3481; Bacteria.
DR   HOGENOM; CLU_056349_2_0_9; -.
DR   OMA; NLVGHLV; -.
DR   Proteomes; UP000001172; Chromosome.
DR   GO; GO:0000175; F:3'-5'-exoribonuclease activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   CDD; cd00077; HDc; 1.
DR   Gene3D; 2.40.50.140; -; 1.
DR   HAMAP; MF_01427; 3_5_Exoribonuc_YhaM; 1.
DR   InterPro; IPR020873; 3'-5'_exoribonuclease_YhaM.
DR   InterPro; IPR003607; HD/PDEase_dom.
DR   InterPro; IPR006674; HD_domain.
DR   InterPro; IPR012340; NA-bd_OB-fold.
DR   Pfam; PF01966; HD; 1.
DR   SMART; SM00471; HDc; 1.
DR   SUPFAM; SSF50249; SSF50249; 1.
DR   PROSITE; PS51831; HD; 1.
PE   3: Inferred from homology;
KW   DNA-binding; Exonuclease; Hydrolase; Nuclease; Reference proteome.
FT   CHAIN           1..325
FT                   /note="3'-5' exoribonuclease YhaM"
FT                   /id="PRO_0000109862"
FT   DOMAIN          163..279
FT                   /note="HD"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01175"
FT   DNA_BIND        14..90
FT                   /note="OB"
SQ   SEQUENCE   325 AA;  36445 MW;  466C134A1BF28B49 CRC64;
     MAKGIIHYEV GEQVDLFLLI KSATKGIASN GKPFLTLILQ DKSGDIEAKL WDVSPDDEER
     YVPECIVKVA GDIHNYRGKL QLRIRSIRPA HPGDAVRIDD FLEKAPLGRE EMKAKVMEYI
     FAMENPNIQR ITRYLLKKYE KAFFEYPAAT KNHHEFISGL AYHVVSMLEL AKALIHLYPS
     LNKDLLYAGV ILHDLGKVIE LSGPVSAAYT LEGNLLGHIS IMVSEISKAA EQLGIQGEEV
     VILQHLVLAH HGKAEWGSPK PPLVKEAEVL HYIDNLDAKI TMIDRALEKV KPGEFTERVF
     ALDNRSFYKP AFLSVSKPKN PGSKE