YHBE_SHIFL
ID YHBE_SHIFL Reviewed; 321 AA.
AC P0AA75; P28636;
DT 13-SEP-2005, integrated into UniProtKB/Swiss-Prot.
DT 13-SEP-2005, sequence version 1.
DT 25-MAY-2022, entry version 95.
DE RecName: Full=Uncharacterized inner membrane transporter YhbE;
GN Name=yhbE; OrderedLocusNames=SF3224, S3442;
OS Shigella flexneri.
OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Shigella.
OX NCBI_TaxID=623;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=301 / Serotype 2a;
RX PubMed=12384590; DOI=10.1093/nar/gkf566;
RA Jin Q., Yuan Z., Xu J., Wang Y., Shen Y., Lu W., Wang J., Liu H., Yang J.,
RA Yang F., Zhang X., Zhang J., Yang G., Wu H., Qu D., Dong J., Sun L.,
RA Xue Y., Zhao A., Gao Y., Zhu J., Kan B., Ding K., Chen S., Cheng H.,
RA Yao Z., He B., Chen R., Ma D., Qiang B., Wen Y., Hou Y., Yu J.;
RT "Genome sequence of Shigella flexneri 2a: insights into pathogenicity
RT through comparison with genomes of Escherichia coli K12 and O157.";
RL Nucleic Acids Res. 30:4432-4441(2002).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 700930 / 2457T / Serotype 2a;
RX PubMed=12704152; DOI=10.1128/iai.71.5.2775-2786.2003;
RA Wei J., Goldberg M.B., Burland V., Venkatesan M.M., Deng W., Fournier G.,
RA Mayhew G.F., Plunkett G. III, Rose D.J., Darling A., Mau B., Perna N.T.,
RA Payne S.M., Runyen-Janecky L.J., Zhou S., Schwartz D.C., Blattner F.R.;
RT "Complete genome sequence and comparative genomics of Shigella flexneri
RT serotype 2a strain 2457T.";
RL Infect. Immun. 71:2775-2786(2003).
CC -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000250}; Multi-pass
CC membrane protein {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the EamA transporter family. {ECO:0000305}.
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DR EMBL; AE005674; AAN44690.1; -; Genomic_DNA.
DR EMBL; AE014073; AAP18504.1; -; Genomic_DNA.
DR RefSeq; NP_708983.1; NC_004337.2.
DR RefSeq; WP_000813037.1; NZ_WPGW01000004.1.
DR AlphaFoldDB; P0AA75; -.
DR SMR; P0AA75; -.
DR STRING; 198214.SF3224; -.
DR EnsemblBacteria; AAN44690; AAN44690; SF3224.
DR EnsemblBacteria; AAP18504; AAP18504; S3442.
DR GeneID; 1027118; -.
DR GeneID; 66672914; -.
DR KEGG; sfl:SF3224; -.
DR KEGG; sfx:S3442; -.
DR PATRIC; fig|198214.7.peg.3825; -.
DR HOGENOM; CLU_074108_1_0_6; -.
DR OMA; FCGANTL; -.
DR OrthoDB; 1515911at2; -.
DR Proteomes; UP000001006; Chromosome.
DR Proteomes; UP000002673; Chromosome.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR InterPro; IPR000620; EamA_dom.
DR Pfam; PF00892; EamA; 2.
PE 3: Inferred from homology;
KW Cell inner membrane; Cell membrane; Membrane; Reference proteome; Repeat;
KW Transmembrane; Transmembrane helix; Transport.
FT CHAIN 1..321
FT /note="Uncharacterized inner membrane transporter YhbE"
FT /id="PRO_0000108171"
FT TOPO_DOM 1..5
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 6..26
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 27..35
FT /note="Periplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 36..56
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 57..70
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 71..91
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 92..99
FT /note="Periplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 100..120
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 121..130
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 131..151
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 152..156
FT /note="Periplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 157..177
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 178..190
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 191..211
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 212..216
FT /note="Periplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 217..237
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 238..249
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 250..270
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 271..278
FT /note="Periplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 279..299
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 300..321
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT DOMAIN 17..144
FT /note="EamA 1"
FT DOMAIN 169..292
FT /note="EamA 2"
SQ SEQUENCE 321 AA; 34963 MW; 9D1E6F9EE30C9518 CRC64;
MKQQAGIGIL LALTTAICWG ALPIAMKQVL EVMEPPTIVF YRFLMASIGL GAILAVKKRL
PPLRVFRKPR WLILLAVATA GLFGNFILFS SSLQYLSPTA SQVIGQLSPV GMMVASVFIL
KEKMRSTQVV GALMLLSGLV MFFNTSLVEI FTKLTDYTWG VIFGVGAATV WVSYGVAQKV
LLRRLASPQI LFLLYTLCTI ALFPLAKPGV IAQLSHWQLA CLIFCGLNTL VGYGALAEAM
ARWQAAQVSA IITLTPLFTL FFSDLLSLAW PDFFARPMLN LLGYLGAFVV VAGAMYSAIG
HRIWGGLRKH TTVVSQPRAG E
