YHBX_ECOLI
ID YHBX_ECOLI Reviewed; 541 AA.
AC P42640; Q2M938; Q46994;
DT 01-NOV-1995, integrated into UniProtKB/Swiss-Prot.
DT 21-FEB-2001, sequence version 2.
DT 03-AUG-2022, entry version 141.
DE RecName: Full=Putative transferase YhbX;
DE EC=2.-.-.-;
GN Name=yhbX; OrderedLocusNames=b3173, JW5534;
OS Escherichia coli (strain K12).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Escherichia.
OX NCBI_TaxID=83333;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=K12 / MG1655 / ATCC 47076;
RX PubMed=9278503; DOI=10.1126/science.277.5331.1453;
RA Blattner F.R., Plunkett G. III, Bloch C.A., Perna N.T., Burland V.,
RA Riley M., Collado-Vides J., Glasner J.D., Rode C.K., Mayhew G.F.,
RA Gregor J., Davis N.W., Kirkpatrick H.A., Goeden M.A., Rose D.J., Mau B.,
RA Shao Y.;
RT "The complete genome sequence of Escherichia coli K-12.";
RL Science 277:1453-1462(1997).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=K12 / W3110 / ATCC 27325 / DSM 5911;
RX PubMed=16738553; DOI=10.1038/msb4100049;
RA Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S.,
RA Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.;
RT "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655
RT and W3110.";
RL Mol. Syst. Biol. 2:E1-E5(2006).
RN [3]
RP SUBCELLULAR LOCATION, AND TOPOLOGY [LARGE SCALE ANALYSIS].
RC STRAIN=K12 / MG1655 / ATCC 47076;
RX PubMed=15919996; DOI=10.1126/science.1109730;
RA Daley D.O., Rapp M., Granseth E., Melen K., Drew D., von Heijne G.;
RT "Global topology analysis of the Escherichia coli inner membrane
RT proteome.";
RL Science 308:1321-1323(2005).
CC -!- FUNCTION: Probably does not transfer phosphoethanolamine to lipid A.
CC {ECO:0000250|UniProtKB:P58216}.
CC -!- SUBCELLULAR LOCATION: Cell inner membrane
CC {ECO:0000269|PubMed:15919996}; Multi-pass membrane protein
CC {ECO:0000305|PubMed:15919996}.
CC -!- SIMILARITY: Belongs to the phosphoethanolamine transferase family.
CC {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=AAA57975.1; Type=Erroneous initiation; Note=Extended N-terminus.; Evidence={ECO:0000305};
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DR EMBL; U18997; AAA57975.1; ALT_INIT; Genomic_DNA.
DR EMBL; U00096; AAC76206.2; -; Genomic_DNA.
DR EMBL; AP009048; BAE77218.1; -; Genomic_DNA.
DR PIR; H65107; H65107.
DR RefSeq; NP_417641.4; NC_000913.3.
DR RefSeq; WP_001333576.1; NZ_LN832404.1.
DR AlphaFoldDB; P42640; -.
DR SMR; P42640; -.
DR BioGRID; 4259423; 23.
DR STRING; 511145.b3173; -.
DR PaxDb; P42640; -.
DR PRIDE; P42640; -.
DR EnsemblBacteria; AAC76206; AAC76206; b3173.
DR EnsemblBacteria; BAE77218; BAE77218; BAE77218.
DR GeneID; 947711; -.
DR KEGG; ecj:JW5534; -.
DR KEGG; eco:b3173; -.
DR PATRIC; fig|511145.12.peg.3267; -.
DR EchoBASE; EB2645; -.
DR eggNOG; COG2194; Bacteria.
DR HOGENOM; CLU_039390_4_1_6; -.
DR OMA; ARRANWG; -.
DR PhylomeDB; P42640; -.
DR BioCyc; EcoCyc:G7655-MON; -.
DR PRO; PR:P42640; -.
DR Proteomes; UP000000318; Chromosome.
DR Proteomes; UP000000625; Chromosome.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005886; C:plasma membrane; IDA:EcoCyc.
DR GO; GO:0016776; F:phosphotransferase activity, phosphate group as acceptor; IBA:GO_Central.
DR GO; GO:0008484; F:sulfuric ester hydrolase activity; IEA:InterPro.
DR GO; GO:0009244; P:lipopolysaccharide core region biosynthetic process; IBA:GO_Central.
DR Gene3D; 3.40.720.10; -; 1.
DR InterPro; IPR017850; Alkaline_phosphatase_core_sf.
DR InterPro; IPR040423; PEA_transferase.
DR InterPro; IPR000917; Sulfatase_N.
DR PANTHER; PTHR30443; PTHR30443; 1.
DR Pfam; PF00884; Sulfatase; 1.
DR SUPFAM; SSF53649; SSF53649; 1.
PE 1: Evidence at protein level;
KW Cell inner membrane; Cell membrane; Membrane; Reference proteome;
KW Transferase; Transmembrane; Transmembrane helix.
FT CHAIN 1..541
FT /note="Putative transferase YhbX"
FT /id="PRO_0000209146"
FT TOPO_DOM 1..60
FT /note="Periplasmic"
FT /evidence="ECO:0000305|PubMed:15919996"
FT TRANSMEM 61..81
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 82..110
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 111..131
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 132..141
FT /note="Periplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 142..162
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 163..264
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 265..285
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 286..541
FT /note="Periplasmic"
FT /evidence="ECO:0000255"
SQ SEQUENCE 541 AA; 60753 MW; CCC4F4FD10374FBA CRC64;
MTVFNKFART FKSHWLLYLC VIVFGITNLV ASSGAHMVQR LLFFVLTILV VKRISSLPLR
LLVAAPFVLL TAADMSISLY SWCTFGTTFN DGFAISVLQS DPDEVVKMLG MYIPYLCAFA
FLSLLFLAVI IKYDVSLPTK KVTGILLLIV ISGSLFSACQ FAYKDAKNKK AFSPYILASR
FATYTPFFNL NYFALAAKEH QRLLSIANTV PYFQLSVRDT GIDTYVLIVG ESVRVDNMSL
YGYTRSTTPQ VEAQRKQIKL FNQAISGAPY TALSVPLSLT ADSVLSHDIH NYPDNIINMA
NQAGFQTFWL SSQSAFRQNG TAVTSIAMRA METVYVRGFD ELLLPHLSQA LQQNTQQKKL
IVLHLNGSHE PACSAYPQSS AVFQPQDDQD ACYDNSIHYT DSLLGQVFEL LKDRRASVMY
FADHGLERDP TKKNVYFHGG REASQQAYHV PMFIWYSPVL GDGVDRTTEN NIFSTAYNNY
LINAWMGVTK PEQPQTLEEV IAHYKGDSRV VDANHDVFDY VMLRKEFTED KQGNPTPEGQ
G
