ID   YHC6_YEAST              Reviewed;         315 AA.
AC   P38740; D3DKU2;
DT   01-FEB-1995, integrated into UniProtKB/Swiss-Prot.
DT   16-MAY-2006, sequence version 2.
DT   03-AUG-2022, entry version 128.
DE   RecName: Full=Uncharacterized protein YHL026C;
GN   OrderedLocusNames=YHL026C;
OS   Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Saccharomyces.
OX   NCBI_TaxID=559292;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 204508 / S288c;
RX   PubMed=8091229; DOI=10.1126/science.8091229;
RA   Johnston M., Andrews S., Brinkman R., Cooper J., Ding H., Dover J., Du Z.,
RA   Favello A., Fulton L., Gattung S., Geisel C., Kirsten J., Kucaba T.,
RA   Hillier L.W., Jier M., Johnston L., Langston Y., Latreille P., Louis E.J.,
RA   Macri C., Mardis E., Menezes S., Mouser L., Nhan M., Rifkin L., Riles L.,
RA   St Peter H., Trevaskis E., Vaughan K., Vignati D., Wilcox L., Wohldman P.,
RA   Waterston R., Wilson R., Vaudin M.;
RT   "Complete nucleotide sequence of Saccharomyces cerevisiae chromosome
RT   VIII.";
RL   Science 265:2077-2082(1994).
RN   [2]
RP   SEQUENCE REVISION TO N-TERMINUS.
RA   Hong E.L.;
RL   Submitted (NOV-2005) to the EMBL/GenBank/DDBJ databases.
RN   [3]
RP   GENOME REANNOTATION.
RC   STRAIN=ATCC 204508 / S288c;
RX   PubMed=24374639; DOI=10.1534/g3.113.008995;
RA   Engel S.R., Dietrich F.S., Fisk D.G., Binkley G., Balakrishnan R.,
RA   Costanzo M.C., Dwight S.S., Hitz B.C., Karra K., Nash R.S., Weng S.,
RA   Wong E.D., Lloyd P., Skrzypek M.S., Miyasato S.R., Simison M., Cherry J.M.;
RT   "The reference genome sequence of Saccharomyces cerevisiae: Then and now.";
RL   G3 (Bethesda) 4:389-398(2014).
RN   [4]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 48-315.
RC   STRAIN=ATCC 204508 / S288c;
RX   PubMed=17322287; DOI=10.1101/gr.6037607;
RA   Hu Y., Rolfs A., Bhullar B., Murthy T.V.S., Zhu C., Berger M.F.,
RA   Camargo A.A., Kelley F., McCarron S., Jepson D., Richardson A., Raphael J.,
RA   Moreira D., Taycher E., Zuo D., Mohr S., Kane M.F., Williamson J.,
RA   Simpson A.J.G., Bulyk M.L., Harlow E., Marsischky G., Kolodner R.D.,
RA   LaBaer J.;
RT   "Approaching a complete repository of sequence-verified protein-encoding
RT   clones for Saccharomyces cerevisiae.";
RL   Genome Res. 17:536-543(2007).
RN   [5]
RP   IDENTIFICATION OF FRAMESHIFT.
RX   PubMed=12775844; DOI=10.1126/science.1084337;
RA   Cliften P.F., Sudarsanam P., Desikan A., Fulton L., Fulton B., Majors J.,
RA   Waterston R., Cohen B.A., Johnston M.;
RT   "Finding functional features in Saccharomyces genomes by phylogenetic
RT   footprinting.";
RL   Science 301:71-76(2003).
RN   [6]
RP   LEVEL OF PROTEIN EXPRESSION [LARGE SCALE ANALYSIS].
RX   PubMed=14562106; DOI=10.1038/nature02046;
RA   Ghaemmaghami S., Huh W.-K., Bower K., Howson R.W., Belle A., Dephoure N.,
RA   O'Shea E.K., Weissman J.S.;
RT   "Global analysis of protein expression in yeast.";
RL   Nature 425:737-741(2003).
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
CC   -!- MISCELLANEOUS: Present with 830 molecules/cell in log phase SD medium.
CC       {ECO:0000269|PubMed:14562106}.
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DR   EMBL; U11583; AAB65062.2; -; Genomic_DNA.
DR   EMBL; AY558104; AAS56430.1; -; Genomic_DNA.
DR   EMBL; BK006934; DAA06659.1; -; Genomic_DNA.
DR   PIR; S48942; S48942.
DR   RefSeq; NP_011837.2; NM_001179106.1.
DR   AlphaFoldDB; P38740; -.
DR   BioGRID; 36396; 27.
DR   DIP; DIP-2744N; -.
DR   IntAct; P38740; 2.
DR   MINT; P38740; -.
DR   STRING; 4932.YHL026C; -.
DR   PaxDb; P38740; -.
DR   EnsemblFungi; YHL026C_mRNA; YHL026C; YHL026C.
DR   GeneID; 856359; -.
DR   KEGG; sce:YHL026C; -.
DR   SGD; S000001018; YHL026C.
DR   VEuPathDB; FungiDB:YHL026C; -.
DR   eggNOG; ENOG502S4IY; Eukaryota.
DR   HOGENOM; CLU_076682_0_0_1; -.
DR   InParanoid; P38740; -.
DR   OMA; TGHQLFY; -.
DR   BioCyc; YEAST:G3O-31046-MON; -.
DR   PRO; PR:P38740; -.
DR   Proteomes; UP000002311; Chromosome VIII.
DR   RNAct; P38740; protein.
DR   GO; GO:0071944; C:cell periphery; HDA:SGD.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   InterPro; IPR018852; DUF2456.
DR   PANTHER; PTHR28297; PTHR28297; 1.
DR   Pfam; PF10445; DUF2456; 1.
PE   1: Evidence at protein level;
KW   Membrane; Reference proteome; Transmembrane; Transmembrane helix.
FT   CHAIN           1..315
FT                   /note="Uncharacterized protein YHL026C"
FT                   /id="PRO_0000014325"
FT   TRANSMEM        18..38
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        202..222
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        244..264
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   REGION          288..315
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   315 AA;  35717 MW;  645BD3279530388F CRC64;
     MKSSEPAPAT PTGFRNSIWF IIFYLFVIQA LGSAIISGGI EFAIAYAMYH SRVDLITLWA
     FPHTISGDCA LSLFIQVGLT WASEEILVGF DDYKRPVFRL NKWITKPSPL KTESNEEIPP
     PKKRFIVDYF ESKDNVVAKQ NTLYHKHNWL FGYLEVNRGI IPKGKEATLK GFLTSQFIHD
     STQSKFMNFI EWFVQKFIRS MILAIAMFIV IWPVTMGILA GIGHKVGSHD YYFNDYPLPQ
     VMKLIYAVVI AFVCTPVAII VIVLRNQFHE ELYYEGLANG TLQQDQEVCS TGNRSSGSTD
     QDISTTKQQS QEAVA