ID   YHCB_ECOLI              Reviewed;         132 AA.
AC   P0ADW3; P39436; Q2M8Y0;
DT   06-DEC-2005, integrated into UniProtKB/Swiss-Prot.
DT   04-DEC-2007, sequence version 2.
DT   03-AUG-2022, entry version 106.
DE   RecName: Full=Inner membrane protein YhcB;
GN   Name=yhcB; OrderedLocusNames=b3233, JW5539;
OS   Escherichia coli (strain K12).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Escherichia.
OX   NCBI_TaxID=83333;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=K12 / MG1655 / ATCC 47076;
RX   PubMed=9278503; DOI=10.1126/science.277.5331.1453;
RA   Blattner F.R., Plunkett G. III, Bloch C.A., Perna N.T., Burland V.,
RA   Riley M., Collado-Vides J., Glasner J.D., Rode C.K., Mayhew G.F.,
RA   Gregor J., Davis N.W., Kirkpatrick H.A., Goeden M.A., Rose D.J., Mau B.,
RA   Shao Y.;
RT   "The complete genome sequence of Escherichia coli K-12.";
RL   Science 277:1453-1462(1997).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=K12 / W3110 / ATCC 27325 / DSM 5911;
RX   PubMed=16738553; DOI=10.1038/msb4100049;
RA   Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S.,
RA   Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.;
RT   "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655
RT   and W3110.";
RL   Mol. Syst. Biol. 2:E1-E5(2006).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 8-132.
RC   STRAIN=K12 / W3110 / ATCC 27325 / DSM 5911;
RA   Bass S., Gu Q., Goddard A.;
RL   Submitted (OCT-1994) to the EMBL/GenBank/DDBJ databases.
RN   [4]
RP   IDENTIFICATION BY MASS SPECTROMETRY, AND SUBCELLULAR LOCATION.
RC   STRAIN=BL21-DE3;
RX   PubMed=16079137; DOI=10.1074/jbc.m506479200;
RA   Stenberg F., Chovanec P., Maslen S.L., Robinson C.V., Ilag L.,
RA   von Heijne G., Daley D.O.;
RT   "Protein complexes of the Escherichia coli cell envelope.";
RL   J. Biol. Chem. 280:34409-34419(2005).
RN   [5]
RP   DISRUPTION PHENOTYPE.
RX   PubMed=16863643; DOI=10.1016/j.bbabio.2006.05.043;
RA   Mogi T., Mizuochi-Asai E., Endou S., Akimoto S., Nakamura H.;
RT   "Role of a putative third subunit YhcB on the assembly and function of
RT   cytochrome bd-type ubiquinol oxidase from Escherichia coli.";
RL   Biochim. Biophys. Acta 1757:860-864(2006).
RN   [6]
RP   SUBUNIT, SUBCELLULAR LOCATION, AND TOPOLOGY.
RC   STRAIN=BL21-DE3;
RX   PubMed=21210718; DOI=10.1021/pr101105c;
RA   Maddalo G., Stenberg-Bruzell F., Gotzke H., Toddo S., Bjorkholm P.,
RA   Eriksson H., Chovanec P., Genevaux P., Lehtio J., Ilag L.L., Daley D.O.;
RT   "Systematic analysis of native membrane protein complexes in Escherichia
RT   coli.";
RL   J. Proteome Res. 10:1848-1859(2011).
CC   -!- SUBUNIT: Forms homooligomers. {ECO:0000269|PubMed:21210718}.
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000269|PubMed:16079137,
CC       ECO:0000269|PubMed:21210718}; Single-pass membrane protein
CC       {ECO:0000269|PubMed:16079137, ECO:0000269|PubMed:21210718}.
CC   -!- DISRUPTION PHENOTYPE: No change in function or assembly of the
CC       cytochrome bd-I complex. {ECO:0000269|PubMed:16863643}.
CC   -!- SIMILARITY: To H.influenzae HI_1628. {ECO:0000305}.
CC   -!- CAUTION: Was originally thought to be a member of the cytochrome bd-I
CC       complex (PubMed:16079137). Subsequent work suggests this is not the
CC       case (PubMed:16863643). {ECO:0000305|PubMed:16079137,
CC       ECO:0000305|PubMed:16863643}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=AAA58035.1; Type=Erroneous initiation; Note=Extended N-terminus.; Evidence={ECO:0000305};
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DR   EMBL; U18997; AAA58035.1; ALT_INIT; Genomic_DNA.
DR   EMBL; U00096; AAC76265.2; -; Genomic_DNA.
DR   EMBL; AP009048; BAE77276.1; -; Genomic_DNA.
DR   EMBL; U15661; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   PIR; C65115; C65115.
DR   RefSeq; NP_417700.2; NC_000913.3.
DR   RefSeq; WP_001295270.1; NZ_STEB01000012.1.
DR   AlphaFoldDB; P0ADW3; -.
DR   SMR; P0ADW3; -.
DR   BioGRID; 4261916; 492.
DR   DIP; DIP-39900N; -.
DR   IntAct; P0ADW3; 1.
DR   STRING; 511145.b3233; -.
DR   jPOST; P0ADW3; -.
DR   PaxDb; P0ADW3; -.
DR   PRIDE; P0ADW3; -.
DR   EnsemblBacteria; AAC76265; AAC76265; b3233.
DR   EnsemblBacteria; BAE77276; BAE77276; BAE77276.
DR   GeneID; 66672871; -.
DR   GeneID; 947815; -.
DR   KEGG; ecj:JW5539; -.
DR   KEGG; eco:b3233; -.
DR   PATRIC; fig|511145.12.peg.3330; -.
DR   EchoBASE; EB2498; -.
DR   eggNOG; COG3105; Bacteria.
DR   HOGENOM; CLU_135606_1_0_6; -.
DR   InParanoid; P0ADW3; -.
DR   OMA; HMAKTSS; -.
DR   PhylomeDB; P0ADW3; -.
DR   BioCyc; EcoCyc:G7681-MON; -.
DR   PRO; PR:P0ADW3; -.
DR   Proteomes; UP000000318; Chromosome.
DR   Proteomes; UP000000625; Chromosome.
DR   GO; GO:0005887; C:integral component of plasma membrane; ISM:EcoCyc.
DR   GO; GO:0005886; C:plasma membrane; IDA:EcoCyc.
DR   InterPro; IPR009386; DUF1043.
DR   PANTHER; PTHR39579; PTHR39579; 1.
DR   Pfam; PF06295; DUF1043; 1.
DR   PIRSF; PIRSF006318; YhcB; 1.
PE   1: Evidence at protein level;
KW   Cell inner membrane; Cell membrane; Membrane; Reference proteome;
KW   Transmembrane; Transmembrane helix.
FT   CHAIN           1..132
FT                   /note="Inner membrane protein YhcB"
FT                   /id="PRO_0000169477"
FT   TRANSMEM        1..21
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        22..132
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000305|PubMed:21210718"
FT   REGION          95..132
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   132 AA;  14961 MW;  6A57A58B5FD1C171 CRC64;
     MTWEYALIGL VVGIIIGAVA MRFGNRKLRQ QQALQYELEK NKAELDEYRE ELVSHFARSA
     ELLDTMAHDY RQLYQHMAKS SSSLLPELSA EANPFRNRLA ESEASNDQAP VQMPRDYSEG
     ASGLLRTGAK RD