YHDG_BACSU
ID YHDG_BACSU Reviewed; 465 AA.
AC O07576; Q796X7;
DT 20-JAN-2009, integrated into UniProtKB/Swiss-Prot.
DT 01-JUL-1997, sequence version 1.
DT 03-AUG-2022, entry version 125.
DE RecName: Full=Uncharacterized amino acid permease YhdG;
GN Name=yhdG; OrderedLocusNames=BSU09460;
OS Bacillus subtilis (strain 168).
OC Bacteria; Firmicutes; Bacilli; Bacillales; Bacillaceae; Bacillus.
OX NCBI_TaxID=224308;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=168;
RX PubMed=9579061; DOI=10.1099/00221287-144-4-859;
RA Noback M.A., Holsappel S., Kiewiet R., Terpstra P., Wambutt R., Wedler H.,
RA Venema G., Bron S.;
RT "The 172 kb prkA-addAB region from 83 degrees to 97 degrees of the Bacillus
RT subtilis chromosome contains several dysfunctional genes, the glyB marker,
RT many genes encoding transporter proteins, and the ubiquitous hit gene.";
RL Microbiology 144:859-875(1998).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=168;
RX PubMed=9384377; DOI=10.1038/36786;
RA Kunst F., Ogasawara N., Moszer I., Albertini A.M., Alloni G., Azevedo V.,
RA Bertero M.G., Bessieres P., Bolotin A., Borchert S., Borriss R.,
RA Boursier L., Brans A., Braun M., Brignell S.C., Bron S., Brouillet S.,
RA Bruschi C.V., Caldwell B., Capuano V., Carter N.M., Choi S.-K.,
RA Codani J.-J., Connerton I.F., Cummings N.J., Daniel R.A., Denizot F.,
RA Devine K.M., Duesterhoeft A., Ehrlich S.D., Emmerson P.T., Entian K.-D.,
RA Errington J., Fabret C., Ferrari E., Foulger D., Fritz C., Fujita M.,
RA Fujita Y., Fuma S., Galizzi A., Galleron N., Ghim S.-Y., Glaser P.,
RA Goffeau A., Golightly E.J., Grandi G., Guiseppi G., Guy B.J., Haga K.,
RA Haiech J., Harwood C.R., Henaut A., Hilbert H., Holsappel S., Hosono S.,
RA Hullo M.-F., Itaya M., Jones L.-M., Joris B., Karamata D., Kasahara Y.,
RA Klaerr-Blanchard M., Klein C., Kobayashi Y., Koetter P., Koningstein G.,
RA Krogh S., Kumano M., Kurita K., Lapidus A., Lardinois S., Lauber J.,
RA Lazarevic V., Lee S.-M., Levine A., Liu H., Masuda S., Mauel C.,
RA Medigue C., Medina N., Mellado R.P., Mizuno M., Moestl D., Nakai S.,
RA Noback M., Noone D., O'Reilly M., Ogawa K., Ogiwara A., Oudega B.,
RA Park S.-H., Parro V., Pohl T.M., Portetelle D., Porwollik S.,
RA Prescott A.M., Presecan E., Pujic P., Purnelle B., Rapoport G., Rey M.,
RA Reynolds S., Rieger M., Rivolta C., Rocha E., Roche B., Rose M., Sadaie Y.,
RA Sato T., Scanlan E., Schleich S., Schroeter R., Scoffone F., Sekiguchi J.,
RA Sekowska A., Seror S.J., Serror P., Shin B.-S., Soldo B., Sorokin A.,
RA Tacconi E., Takagi T., Takahashi H., Takemaru K., Takeuchi M.,
RA Tamakoshi A., Tanaka T., Terpstra P., Tognoni A., Tosato V., Uchiyama S.,
RA Vandenbol M., Vannier F., Vassarotti A., Viari A., Wambutt R., Wedler E.,
RA Wedler H., Weitzenegger T., Winters P., Wipat A., Yamamoto H., Yamane K.,
RA Yasumoto K., Yata K., Yoshida K., Yoshikawa H.-F., Zumstein E.,
RA Yoshikawa H., Danchin A.;
RT "The complete genome sequence of the Gram-positive bacterium Bacillus
RT subtilis.";
RL Nature 390:249-256(1997).
RN [3]
RP INDUCTION.
RX PubMed=12618455; DOI=10.1128/jb.185.6.1911-1922.2003;
RA Molle V., Nakaura Y., Shivers R.P., Yamaguchi H., Losick R., Fujita Y.,
RA Sonenshein A.L.;
RT "Additional targets of the Bacillus subtilis global regulator CodY
RT identified by chromatin immunoprecipitation and genome-wide transcript
RT analysis.";
RL J. Bacteriol. 185:1911-1922(2003).
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC protein {ECO:0000305}.
CC -!- INDUCTION: Repressed by CodY. {ECO:0000269|PubMed:12618455}.
CC -!- SIMILARITY: Belongs to the amino acid-polyamine-organocation (APC)
CC superfamily. {ECO:0000305}.
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DR EMBL; Y14082; CAA74491.1; -; Genomic_DNA.
DR EMBL; AL009126; CAB12785.1; -; Genomic_DNA.
DR PIR; E69825; E69825.
DR RefSeq; NP_388827.1; NC_000964.3.
DR RefSeq; WP_003245791.1; NZ_JNCM01000035.1.
DR AlphaFoldDB; O07576; -.
DR SMR; O07576; -.
DR STRING; 224308.BSU09460; -.
DR PaxDb; O07576; -.
DR EnsemblBacteria; CAB12785; CAB12785; BSU_09460.
DR GeneID; 939746; -.
DR KEGG; bsu:BSU09460; -.
DR PATRIC; fig|224308.179.peg.1019; -.
DR eggNOG; COG0531; Bacteria.
DR InParanoid; O07576; -.
DR OMA; GWSMIMD; -.
DR PhylomeDB; O07576; -.
DR BioCyc; BSUB:BSU09460-MON; -.
DR Proteomes; UP000001570; Chromosome.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015171; F:amino acid transmembrane transporter activity; IBA:GO_Central.
DR GO; GO:0006865; P:amino acid transport; IBA:GO_Central.
DR InterPro; IPR002293; AA/rel_permease1.
DR InterPro; IPR004758; AA_transporter.
DR Pfam; PF13520; AA_permease_2; 1.
DR TIGRFAMs; TIGR00909; 2A0306; 1.
PE 2: Evidence at transcript level;
KW Cell membrane; Membrane; Reference proteome; Transmembrane;
KW Transmembrane helix.
FT CHAIN 1..465
FT /note="Uncharacterized amino acid permease YhdG"
FT /id="PRO_0000360836"
FT TRANSMEM 35..55
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 57..77
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 133..153
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 159..179
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 188..208
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 216..236
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 258..278
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 305..325
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 355..375
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 380..400
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 413..432
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 437..456
FT /note="Helical"
FT /evidence="ECO:0000255"
SQ SEQUENCE 465 AA; 49711 MW; CC4A815DBA426A94 CRC64;
MKGSVFRKKS IQDLIAATSG EKSLKRELGA FDLTLLGIGA IIGTGIFVLT GTGAVTAGPG
LTISFVVAAL ACLFAALSYA EFASSVPVSG SVYTFTYATL GELMAFIIGW DLILEYMLAV
SAVSVGWSGY FQSFLSGLGI HLPVALTAAP GAVKGTFTLF NLPAFVIVMA ITYLLYLGIK
ESKRVNNIMV ILKILVVLLF IAVAAVYVKP HNWQPFMPMG FGGVFSAAAL VFFAFIGFDA
VSSAAEETKN PAKDLPKGII FSLLVCTILY VTVSAIMTGV IPFAQFAGVD HPVSLVLQSA
GQNWVAGIID IGAVLGMTTV MLVMLYGQTR VMFAMSRDGL VPGSLSKVHP KHKTPYVATW
FFGTMSALLG SLVPLDELAK LVNIGTLSAF VLISVAVIVL RKKQPDLPRA FKCPGVPVIP
GLAILFCLFL ILNLGWVTIV RFLVWLLIGL VIYFLYSRKH SKLNQ
