ID   YHDT_ECOLI              Reviewed;          80 AA.
AC   P45566; Q2M8V8;
DT   01-NOV-1995, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1995, sequence version 1.
DT   03-AUG-2022, entry version 136.
DE   RecName: Full=Uncharacterized membrane protein YhdT {ECO:0000305};
GN   Name=yhdT; OrderedLocusNames=b3257, JW3225;
OS   Escherichia coli (strain K12).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Escherichia.
OX   NCBI_TaxID=83333;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=K12;
RX   PubMed=2193919; DOI=10.1128/jb.172.7.3842-3848.1990;
RA   Jackowski S., Alix J.-H.;
RT   "Cloning, sequence, and expression of the pantothenate permease (panF) gene
RT   of Escherichia coli.";
RL   J. Bacteriol. 172:3842-3848(1990).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RA   Best E.A., Knauf V.C.;
RT   "Cloning and characterization of the E. coli fabEG operon encoding subunits
RT   of acetyl-CoA carboxylase.";
RL   Submitted (JUL-1992) to the EMBL/GenBank/DDBJ databases.
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=K12 / MG1655 / ATCC 47076;
RX   PubMed=9278503; DOI=10.1126/science.277.5331.1453;
RA   Blattner F.R., Plunkett G. III, Bloch C.A., Perna N.T., Burland V.,
RA   Riley M., Collado-Vides J., Glasner J.D., Rode C.K., Mayhew G.F.,
RA   Gregor J., Davis N.W., Kirkpatrick H.A., Goeden M.A., Rose D.J., Mau B.,
RA   Shao Y.;
RT   "The complete genome sequence of Escherichia coli K-12.";
RL   Science 277:1453-1462(1997).
RN   [4]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=K12 / W3110 / ATCC 27325 / DSM 5911;
RX   PubMed=16738553; DOI=10.1038/msb4100049;
RA   Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S.,
RA   Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.;
RT   "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655
RT   and W3110.";
RL   Mol. Syst. Biol. 2:E1-E5(2006).
RN   [5]
RP   INDUCTION.
RC   STRAIN=K12 / BW25113;
RX   PubMed=25346166; DOI=10.1080/09168451.2014.972328;
RA   Yamamoto K., Nonaka G., Ozawa T., Takumi K., Ishihama A.;
RT   "Induction of the Escherichia coli yijE gene expression by cystine.";
RL   Biosci. Biotechnol. Biochem. 79:218-222(2015).
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000255}.
CC   -!- INDUCTION: Down-regulated by cystine. {ECO:0000269|PubMed:25346166}.
CC   -!- SIMILARITY: To H.influenzae HI_0974B. {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=M30953; Type=Frameshift; Evidence={ECO:0000305};
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DR   EMBL; M30953; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; M83198; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; U18997; AAA58060.1; -; Genomic_DNA.
DR   EMBL; U00096; AAC76289.1; -; Genomic_DNA.
DR   EMBL; AP009048; BAE77298.1; -; Genomic_DNA.
DR   PIR; C65118; C65118.
DR   RefSeq; NP_417723.1; NC_000913.3.
DR   RefSeq; WP_000381173.1; NZ_SSZK01000034.1.
DR   AlphaFoldDB; P45566; -.
DR   SMR; P45566; -.
DR   BioGRID; 4263369; 11.
DR   STRING; 511145.b3257; -.
DR   PaxDb; P45566; -.
DR   PRIDE; P45566; -.
DR   DNASU; 947762; -.
DR   EnsemblBacteria; AAC76289; AAC76289; b3257.
DR   EnsemblBacteria; BAE77298; BAE77298; BAE77298.
DR   GeneID; 947762; -.
DR   KEGG; ecj:JW3225; -.
DR   KEGG; eco:b3257; -.
DR   PATRIC; fig|1411691.4.peg.3471; -.
DR   EchoBASE; EB2680; -.
DR   eggNOG; COG3924; Bacteria.
DR   HOGENOM; CLU_166678_1_0_6; -.
DR   OMA; WFELACL; -.
DR   PhylomeDB; P45566; -.
DR   BioCyc; EcoCyc:G7693-MON; -.
DR   PRO; PR:P45566; -.
DR   Proteomes; UP000000318; Chromosome.
DR   Proteomes; UP000000625; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   InterPro; IPR010398; DUF997.
DR   PANTHER; PTHR39174; PTHR39174; 1.
DR   Pfam; PF06196; DUF997; 1.
PE   2: Evidence at transcript level;
KW   Cell membrane; Membrane; Reference proteome; Transmembrane;
KW   Transmembrane helix.
FT   CHAIN           1..80
FT                   /note="Uncharacterized membrane protein YhdT"
FT                   /id="PRO_0000169497"
FT   TRANSMEM        15..35
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        45..65
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   80 AA;  9098 MW;  D1B46228E2AB93DC CRC64;
     MDTRFVQAHK EARWALGLTL LYLAVWLVAA YLSGVAPGFT GFPRWFEMAC ILTPLLFIGL
     CWAMVKFIYR DIPLEDDDAA