YHDX_ECOLI
ID YHDX_ECOLI Reviewed; 393 AA.
AC P45767; Q2M8U6; Q6BF40;
DT 01-NOV-1995, integrated into UniProtKB/Swiss-Prot.
DT 11-OCT-2004, sequence version 3.
DT 03-AUG-2022, entry version 140.
DE RecName: Full=Putative amino-acid ABC transporter permease protein YhdX;
GN Name=yhdX; OrderedLocusNames=b3269, JW5544;
OS Escherichia coli (strain K12).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Escherichia.
OX NCBI_TaxID=83333;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=K12 / MG1655 / ATCC 47076;
RX PubMed=9278503; DOI=10.1126/science.277.5331.1453;
RA Blattner F.R., Plunkett G. III, Bloch C.A., Perna N.T., Burland V.,
RA Riley M., Collado-Vides J., Glasner J.D., Rode C.K., Mayhew G.F.,
RA Gregor J., Davis N.W., Kirkpatrick H.A., Goeden M.A., Rose D.J., Mau B.,
RA Shao Y.;
RT "The complete genome sequence of Escherichia coli K-12.";
RL Science 277:1453-1462(1997).
RN [2]
RP SEQUENCE REVISION.
RX PubMed=16397293; DOI=10.1093/nar/gkj405;
RA Riley M., Abe T., Arnaud M.B., Berlyn M.K.B., Blattner F.R.,
RA Chaudhuri R.R., Glasner J.D., Horiuchi T., Keseler I.M., Kosuge T.,
RA Mori H., Perna N.T., Plunkett G. III, Rudd K.E., Serres M.H., Thomas G.H.,
RA Thomson N.R., Wishart D., Wanner B.L.;
RT "Escherichia coli K-12: a cooperatively developed annotation snapshot
RT -- 2005.";
RL Nucleic Acids Res. 34:1-9(2006).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=K12 / W3110 / ATCC 27325 / DSM 5911;
RX PubMed=16738553; DOI=10.1038/msb4100049;
RA Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S.,
RA Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.;
RT "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655
RT and W3110.";
RL Mol. Syst. Biol. 2:E1-E5(2006).
CC -!- FUNCTION: Probably part of the binding-protein-dependent transport
CC system YdhWXYZ for an amino acid; probably responsible for the
CC translocation of the substrate across the membrane.
CC -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000305}; Multi-pass
CC membrane protein {ECO:0000255|PROSITE-ProRule:PRU00441}.
CC -!- SIMILARITY: Belongs to the binding-protein-dependent transport system
CC permease family. HisMQ subfamily. {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=AAA58073.1; Type=Frameshift; Evidence={ECO:0000305};
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; U18997; AAA58073.1; ALT_FRAME; Genomic_DNA.
DR EMBL; U00096; AAT48174.1; -; Genomic_DNA.
DR EMBL; AP009048; BAE77310.1; -; Genomic_DNA.
DR RefSeq; WP_000019655.1; NZ_STEB01000012.1.
DR RefSeq; YP_026209.1; NC_000913.3.
DR AlphaFoldDB; P45767; -.
DR SMR; P45767; -.
DR BioGRID; 4260867; 5.
DR ComplexPortal; CPX-4450; Putative amino acid ABC transporter complex.
DR STRING; 511145.b3269; -.
DR TCDB; 3.A.1.3.26; the atp-binding cassette (abc) superfamily.
DR PaxDb; P45767; -.
DR PRIDE; P45767; -.
DR EnsemblBacteria; AAT48174; AAT48174; b3269.
DR EnsemblBacteria; BAE77310; BAE77310; BAE77310.
DR GeneID; 66672837; -.
DR GeneID; 947765; -.
DR KEGG; ecj:JW5544; -.
DR KEGG; eco:b3269; -.
DR PATRIC; fig|1411691.4.peg.3458; -.
DR EchoBASE; EB2684; -.
DR eggNOG; COG4597; Bacteria.
DR HOGENOM; CLU_019602_8_0_6; -.
DR InParanoid; P45767; -.
DR OMA; ILFWYFA; -.
DR PhylomeDB; P45767; -.
DR BioCyc; EcoCyc:YHDX-MON; -.
DR PRO; PR:P45767; -.
DR Proteomes; UP000000318; Chromosome.
DR Proteomes; UP000000625; Chromosome.
DR GO; GO:0055052; C:ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing; IC:ComplexPortal.
DR GO; GO:0016020; C:membrane; IC:ComplexPortal.
DR GO; GO:0005886; C:plasma membrane; IDA:EcoCyc.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR GO; GO:0006865; P:amino acid transport; IBA:GO_Central.
DR GO; GO:0015833; P:peptide transport; IC:ComplexPortal.
DR CDD; cd06261; TM_PBP2; 1.
DR Gene3D; 1.10.3720.10; -; 2.
DR InterPro; IPR010065; AA_ABC_transptr_permease_3TM.
DR InterPro; IPR043429; ArtM/GltK/GlnP/TcyL/YhdX-like.
DR InterPro; IPR000515; MetI-like.
DR InterPro; IPR035906; MetI-like_sf.
DR PANTHER; PTHR30614; PTHR30614; 1.
DR Pfam; PF00528; BPD_transp_1; 1.
DR SUPFAM; SSF161098; SSF161098; 2.
DR TIGRFAMs; TIGR01726; HEQRo_perm_3TM; 1.
DR PROSITE; PS50928; ABC_TM1; 1.
PE 3: Inferred from homology;
KW Amino-acid transport; Cell inner membrane; Cell membrane; Membrane;
KW Reference proteome; Transmembrane; Transmembrane helix; Transport.
FT CHAIN 1..393
FT /note="Putative amino-acid ABC transporter permease protein
FT YhdX"
FT /id="PRO_0000060253"
FT TRANSMEM 21..41
FT /note="Helical"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT TRANSMEM 92..112
FT /note="Helical"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT TRANSMEM 128..148
FT /note="Helical"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT TRANSMEM 180..200
FT /note="Helical"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT TRANSMEM 219..239
FT /note="Helical"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT TRANSMEM 256..276
FT /note="Helical"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT TRANSMEM 333..353
FT /note="Helical"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT TRANSMEM 363..383
FT /note="Helical"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT DOMAIN 88..381
FT /note="ABC transmembrane type-1"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
SQ SEQUENCE 393 AA; 43261 MW; EE95D98184216D22 CRC64;
MSHRRSTVKG SLSFANPTVR AWLFQILAVV AVVGIVGWLF HNTVTNLNNR GITSGFAFLD
RGAGFGIVQH LIDYQQGDTY GRVFIVGLLN TLLVSALCIV FASVLGFFIG LARLSDNWLL
RKLSTIYIEI FRNIPPLLQI FFWYFAVLRN LPGPRQAVSA FDLAFLSNRG LYIPSPQLGD
GFIAFILAVV MAIVLSVGLF RFNKTYQIKT GQLRRTWPIA AVLIIGLPLL AQWLFGAALH
WDVPALRGFN FRGGMVLIPE LAALTLALSV YTSAFIAEII RAGIQAVPYG QHEAARSLGL
PNPVTLRQVI IPQALRVIIP PLTSQYLNIV KNSSLAAAIG YPDMVSLFAG TVLNQTGQAI
ETIAMTMSVY LIISLTISLL MNIYNRRIAI VER
