ID   YHEB_SCHPO              Reviewed;         365 AA.
AC   Q9HDU4;
DT   05-FEB-2008, integrated into UniProtKB/Swiss-Prot.
DT   01-MAR-2001, sequence version 1.
DT   25-MAY-2022, entry version 108.
DE   RecName: Full=Uncharacterized protein PB2B2.11;
GN   ORFNames=SPBPB2B2.11;
OS   Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina;
OC   Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae;
OC   Schizosaccharomyces.
OX   NCBI_TaxID=284812;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=972 / ATCC 24843;
RX   PubMed=11859360; DOI=10.1038/nature724;
RA   Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A.,
RA   Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S.,
RA   Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M.,
RA   Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S.,
RA   Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S.,
RA   Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D.,
RA   Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P.,
RA   Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K.,
RA   O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M.,
RA   Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N.,
RA   Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A.,
RA   Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R.,
RA   Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M.,
RA   Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A.,
RA   Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A.,
RA   Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H.,
RA   Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S.,
RA   Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C.,
RA   Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A.,
RA   Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M.,
RA   del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S.,
RA   Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R.,
RA   Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G.,
RA   Nurse P.;
RT   "The genome sequence of Schizosaccharomyces pombe.";
RL   Nature 415:871-880(2002).
RN   [2]
RP   SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
RX   PubMed=16823372; DOI=10.1038/nbt1222;
RA   Matsuyama A., Arai R., Yashiroda Y., Shirai A., Kamata A., Sekido S.,
RA   Kobayashi Y., Hashimoto A., Hamamoto M., Hiraoka Y., Horinouchi S.,
RA   Yoshida M.;
RT   "ORFeome cloning and global analysis of protein localization in the fission
RT   yeast Schizosaccharomyces pombe.";
RL   Nat. Biotechnol. 24:841-847(2006).
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000269|PubMed:16823372}. Nucleus
CC       {ECO:0000269|PubMed:16823372}.
CC   -!- SIMILARITY: Belongs to the NAD(P)-dependent epimerase/dehydratase
CC       family. {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; CU329671; CAC21413.1; -; Genomic_DNA.
DR   RefSeq; NP_596857.1; NM_001023880.2.
DR   AlphaFoldDB; Q9HDU4; -.
DR   SMR; Q9HDU4; -.
DR   BioGRID; 277907; 7.
DR   STRING; 4896.SPBPB2B2.11.1; -.
DR   PaxDb; Q9HDU4; -.
DR   EnsemblFungi; SPBPB2B2.11.1; SPBPB2B2.11.1:pep; SPBPB2B2.11.
DR   GeneID; 2541398; -.
DR   KEGG; spo:SPBPB2B2.11; -.
DR   PomBase; SPBPB2B2.11; -.
DR   VEuPathDB; FungiDB:SPBPB2B2.11; -.
DR   eggNOG; KOG0747; Eukaryota.
DR   HOGENOM; CLU_007383_1_14_1; -.
DR   InParanoid; Q9HDU4; -.
DR   OMA; KLIPLMC; -.
DR   PhylomeDB; Q9HDU4; -.
DR   PRO; PR:Q9HDU4; -.
DR   Proteomes; UP000002485; Chromosome II.
DR   GO; GO:0005829; C:cytosol; HDA:PomBase.
DR   GO; GO:0005634; C:nucleus; HDA:PomBase.
DR   GO; GO:0008460; F:dTDP-glucose 4,6-dehydratase activity; ISS:PomBase.
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:InterPro.
DR   GO; GO:0009225; P:nucleotide-sugar metabolic process; IC:PomBase.
DR   InterPro; IPR016040; NAD(P)-bd_dom.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   InterPro; IPR020904; Sc_DH/Rdtase_CS.
DR   Pfam; PF16363; GDP_Man_Dehyd; 1.
DR   SUPFAM; SSF51735; SSF51735; 1.
PE   3: Inferred from homology;
KW   Cytoplasm; Nucleus; Reference proteome.
FT   CHAIN           1..365
FT                   /note="Uncharacterized protein PB2B2.11"
FT                   /id="PRO_0000318144"
SQ   SEQUENCE   365 AA;  42623 MW;  E4AE561A4B4E088A CRC64;
     MTGDYKEYKG YALITGGAGF IGSNFLDYAV DKYPDFHFTC IDKLSYVSNY TTVFLSKVLN
     QPNFRFLEMD LATNYKFLYQ FMVEDSEINK ITHIINFAAE SSVDRSFIDP LYFTKNNILS
     TQNLLECVRI LLGKKEELRN RLNFVHVSTD EVYGEQDENA SVDEKSKLNP TSPYAASKAA
     VDLIIQSYRY SYKISVTVIR ANNVYGPRQY EEKLIPMTLG KLKKFINQKS QKIMQDKITL
     HGDGLHKRKY LHIYDFINAI DLVWMKQGSE VYHSTLESKM SGQIFNIGSD DEIDNLSLVK
     FICDYFLYRK LSLKNLDYSK YITFVQDRNY NDSRYSLNYE KIKSLGWRPQ IPLETGLRKL
     IDEYY