YHEG_SCHPO
ID YHEG_SCHPO Reviewed; 485 AA.
AC P0CU11; Q9P3E8;
DT 07-SEP-2016, integrated into UniProtKB/Swiss-Prot.
DT 07-SEP-2016, sequence version 1.
DT 03-AUG-2022, entry version 26.
DE RecName: Full=Uncharacterized transporter SPBPB2B2.16c;
GN ORFNames=SPBPB2B2.16c;
OS Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina;
OC Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae;
OC Schizosaccharomyces.
OX NCBI_TaxID=284812;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=972 / ATCC 24843;
RX PubMed=11859360; DOI=10.1038/nature724;
RA Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A.,
RA Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S.,
RA Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M.,
RA Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S.,
RA Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S.,
RA Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D.,
RA Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P.,
RA Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K.,
RA O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M.,
RA Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N.,
RA Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A.,
RA Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R.,
RA Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M.,
RA Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A.,
RA Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A.,
RA Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H.,
RA Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S.,
RA Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C.,
RA Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A.,
RA Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M.,
RA del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S.,
RA Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R.,
RA Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G.,
RA Nurse P.;
RT "The genome sequence of Schizosaccharomyces pombe.";
RL Nature 415:871-880(2002).
RN [2]
RP SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
RX PubMed=16823372; DOI=10.1038/nbt1222;
RA Matsuyama A., Arai R., Yashiroda Y., Shirai A., Kamata A., Sekido S.,
RA Kobayashi Y., Hashimoto A., Hamamoto M., Hiraoka Y., Horinouchi S.,
RA Yoshida M.;
RT "ORFeome cloning and global analysis of protein localization in the fission
RT yeast Schizosaccharomyces pombe.";
RL Nat. Biotechnol. 24:841-847(2006).
CC -!- SUBCELLULAR LOCATION: Golgi apparatus {ECO:0000269|PubMed:16823372}.
CC Membrane {ECO:0000255}; Multi-pass membrane protein {ECO:0000255}.
CC -!- SIMILARITY: Belongs to the major facilitator superfamily. CAR1 family.
CC {ECO:0000305}.
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DR EMBL; CU329671; CAC21418.1; -; Genomic_DNA.
DR RefSeq; NP_595028.1; NM_001020458.2.
DR RefSeq; NP_596862.1; NM_001023885.1.
DR AlphaFoldDB; P0CU11; -.
DR SMR; P0CU11; -.
DR STRING; 4896.SPAC750.02c.1; -.
DR EnsemblFungi; SPAC750.02c.1; SPAC750.02c.1:pep; SPAC750.02c.
DR EnsemblFungi; SPBPB2B2.16c.1; SPBPB2B2.16c.1:pep; SPBPB2B2.16c.
DR GeneID; 2541400; -.
DR GeneID; 2541534; -.
DR KEGG; spo:SPAC750.02c; -.
DR KEGG; spo:SPBPB2B2.16c; -.
DR PomBase; SPBPB2B2.16c; -.
DR VEuPathDB; FungiDB:SPAC750.02c; -.
DR VEuPathDB; FungiDB:SPBPB2B2.16c; -.
DR eggNOG; KOG0255; Eukaryota.
DR OMA; TMCAPGI; -.
DR PhylomeDB; P0CU11; -.
DR PRO; PR:P0CU11; -.
DR Proteomes; UP000002485; Chromosome II.
DR GO; GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0022857; F:transmembrane transporter activity; ISM:PomBase.
DR GO; GO:0034220; P:ion transmembrane transport; IEA:UniProt.
DR GO; GO:0055085; P:transmembrane transport; ISM:PomBase.
DR Gene3D; 1.20.1250.20; -; 1.
DR InterPro; IPR011701; MFS.
DR InterPro; IPR020846; MFS_dom.
DR InterPro; IPR036259; MFS_trans_sf.
DR Pfam; PF07690; MFS_1; 1.
DR SUPFAM; SSF103473; SSF103473; 1.
DR PROSITE; PS50850; MFS; 1.
PE 3: Inferred from homology;
KW Golgi apparatus; Membrane; Reference proteome; Transmembrane;
KW Transmembrane helix; Transport.
FT CHAIN 1..485
FT /note="Uncharacterized transporter SPBPB2B2.16c"
FT /id="PRO_0000437232"
FT TRANSMEM 79..99
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 117..137
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 139..159
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 170..190
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 199..219
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 275..295
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 313..333
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 355..375
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 380..400
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 421..441
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 448..468
FT /note="Helical"
FT /evidence="ECO:0000255"
SQ SEQUENCE 485 AA; 54087 MW; 76248FC18F5638AD CRC64;
MKEESILKKC DSSSIKHVPS TPLETNCPDK YNPKTWPIRL KVRNVIVISS MTFLNQYGDS
VFAPSISNIA EQFHASRTLV TLGATLYTLG ILFGNLIFAP LSEQFGRRPI YLIGYSVFAL
LQIPIALSVN LAMFLVFRFF SGLFGSVGLS NGSGSLADLF EKKDRGKYMV IYFTVLSIGP
GIAPIISGFI SQSSIGWQWE FWILLILSGF NLFWAFLLLK ETYPPVLNRK KFEKYGEIGE
NEPVALRLTG KQLLIKLLIL LSMKKPISIL LSQPILICVA CTIGSIYGMI NLVLIAFSEV
WKSSYDFSPG ISGLMYISIT LGLFSAVFIA MPINQKFYSY LVKRNGGEGE PEFRLPMGFI
GITLFEIGIL LFGWTARYKI FWFVPTIGSA IMGGGYIMTS NPLNMYVVDS YGIYSASASA
GVKIFQLLLG AIFPLFAESL FRRLNYGWGC TLLAFILLAC GCSLPILFKY GKQIRNLRPF
DPSKY
