ID   YHES_ECO57              Reviewed;         637 AA.
AC   P63390; P45535;
DT   11-OCT-2004, integrated into UniProtKB/Swiss-Prot.
DT   11-OCT-2004, sequence version 1.
DT   03-AUG-2022, entry version 103.
DE   RecName: Full=Probable ATP-binding protein YheS;
GN   Name=yheS; OrderedLocusNames=Z4713, ECs4203;
OS   Escherichia coli O157:H7.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Escherichia.
OX   NCBI_TaxID=83334;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=O157:H7 / EDL933 / ATCC 700927 / EHEC;
RX   PubMed=11206551; DOI=10.1038/35054089;
RA   Perna N.T., Plunkett G. III, Burland V., Mau B., Glasner J.D., Rose D.J.,
RA   Mayhew G.F., Evans P.S., Gregor J., Kirkpatrick H.A., Posfai G.,
RA   Hackett J., Klink S., Boutin A., Shao Y., Miller L., Grotbeck E.J.,
RA   Davis N.W., Lim A., Dimalanta E.T., Potamousis K., Apodaca J.,
RA   Anantharaman T.S., Lin J., Yen G., Schwartz D.C., Welch R.A.,
RA   Blattner F.R.;
RT   "Genome sequence of enterohaemorrhagic Escherichia coli O157:H7.";
RL   Nature 409:529-533(2001).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=O157:H7 / Sakai / RIMD 0509952 / EHEC;
RX   PubMed=11258796; DOI=10.1093/dnares/8.1.11;
RA   Hayashi T., Makino K., Ohnishi M., Kurokawa K., Ishii K., Yokoyama K.,
RA   Han C.-G., Ohtsubo E., Nakayama K., Murata T., Tanaka M., Tobe T., Iida T.,
RA   Takami H., Honda T., Sasakawa C., Ogasawara N., Yasunaga T., Kuhara S.,
RA   Shiba T., Hattori M., Shinagawa H.;
RT   "Complete genome sequence of enterohemorrhagic Escherichia coli O157:H7 and
RT   genomic comparison with a laboratory strain K-12.";
RL   DNA Res. 8:11-22(2001).
CC   -!- FUNCTION: Genetic data indicate it may be involved in ribosome assembly
CC       or function. {ECO:0000250|UniProtKB:A0A0H2VBH0}.
CC   -!- SIMILARITY: Belongs to the ABC transporter superfamily. ABCF family.
CC       YheS subfamily. {ECO:0000305}.
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DR   EMBL; AE005174; AAG58460.1; -; Genomic_DNA.
DR   EMBL; BA000007; BAB37626.1; -; Genomic_DNA.
DR   PIR; C91154; C91154.
DR   RefSeq; NP_312230.1; NC_002695.1.
DR   RefSeq; WP_000634798.1; NZ_SWKA01000005.1.
DR   AlphaFoldDB; P63390; -.
DR   SMR; P63390; -.
DR   STRING; 155864.EDL933_4556; -.
DR   EnsemblBacteria; AAG58460; AAG58460; Z4713.
DR   EnsemblBacteria; BAB37626; BAB37626; ECs_4203.
DR   GeneID; 66672767; -.
DR   GeneID; 915942; -.
DR   KEGG; ece:Z4713; -.
DR   KEGG; ecs:ECs_4203; -.
DR   PATRIC; fig|386585.9.peg.4387; -.
DR   eggNOG; COG0488; Bacteria.
DR   HOGENOM; CLU_000604_36_0_6; -.
DR   OMA; CTHIADI; -.
DR   Proteomes; UP000000558; Chromosome.
DR   Proteomes; UP000002519; Chromosome.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   Gene3D; 3.40.50.300; -; 2.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR032781; ABC_tran_Xtn.
DR   InterPro; IPR003439; ABC_transporter-like_ATP-bd.
DR   InterPro; IPR017871; ABC_transporter-like_CS.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   Pfam; PF00005; ABC_tran; 2.
DR   Pfam; PF12848; ABC_tran_Xtn; 1.
DR   SMART; SM00382; AAA; 2.
DR   SUPFAM; SSF52540; SSF52540; 2.
DR   PROSITE; PS00211; ABC_TRANSPORTER_1; 2.
DR   PROSITE; PS50893; ABC_TRANSPORTER_2; 2.
PE   3: Inferred from homology;
KW   ATP-binding; Nucleotide-binding; Reference proteome; Repeat.
FT   CHAIN           1..637
FT                   /note="Probable ATP-binding protein YheS"
FT                   /id="PRO_0000093188"
FT   DOMAIN          2..246
FT                   /note="ABC transporter 1"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00434"
FT   DOMAIN          313..527
FT                   /note="ABC transporter 2"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00434"
FT   REGION          523..559
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        527..559
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   BINDING         34..41
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /ligand_label="1"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00434"
FT   BINDING         345..352
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /ligand_label="2"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00434"
SQ   SEQUENCE   637 AA;  71843 MW;  81BC859FC1105EC5 CRC64;
     MIVFSSLQIR RGVRVLLDNA TATINPGQKV GLVGKNGCGK STLLALLKNE ISADGGSYTF
     PGSWQLAWVN QETPALPQAA LEYVIDGDRE YRQLEAQLHD ANERNDGHAI ATIHGKLDAI
     DAWSIRSRAA SLLHGLGFSN EQLERPVSDF SGGWRMRLNL AQALICRSDL LLLDEPTNHL
     DLDAVIWLEK WLKSYQGTLI LISHDRDFLD PIVDKIIHIE QQSMFEYTGN YSSFEVQRAT
     RLAQQQAMYE SQQERVAHLQ SYIDRFRAKA TKAKQAQSRI KMLERMELIA PAHVDNPFRF
     SFRAPESLPN PLLKMEKVSA GYGDRIILDS IKLNLVPGSR IGLLGRNGAG KSTLIKLLAG
     ELAPVSGEIG LAKGIKLGYF AQHQLEYLRA DESPIQHLAR LAPQELEQKL RDYLGGFGFQ
     GDKVTEETRR FSGGEKARLV LALIVWQRPN LLLLDEPTNH LDLDMRQALT EALIEFEGAL
     VVVSHDRHLL RSTTDDLYLV HDRKVEPFDG DLEDYQQWLS DVQKQENQTD EAPKENANSA
     QARKDQKRRE AELRAQTQPL RKEIARLEKE MEKLNAQLAQ AEEKLGDSEL YDQSRKAELT
     ACLQQQASAK SGLEECEMAW LEAQEQLEQM LLEGQSN