ID   YHES_HAEIN              Reviewed;         638 AA.
AC   P44808;
DT   01-NOV-1995, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1995, sequence version 1.
DT   03-AUG-2022, entry version 128.
DE   RecName: Full=Probable ATP-binding protein YheS {ECO:0000305};
GN   Name=yheS {ECO:0000305}; OrderedLocusNames=HI_0658;
OS   Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Pasteurellales;
OC   Pasteurellaceae; Haemophilus.
OX   NCBI_TaxID=71421;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 51907 / DSM 11121 / KW20 / Rd;
RX   PubMed=7542800; DOI=10.1126/science.7542800;
RA   Fleischmann R.D., Adams M.D., White O., Clayton R.A., Kirkness E.F.,
RA   Kerlavage A.R., Bult C.J., Tomb J.-F., Dougherty B.A., Merrick J.M.,
RA   McKenney K., Sutton G.G., FitzHugh W., Fields C.A., Gocayne J.D.,
RA   Scott J.D., Shirley R., Liu L.-I., Glodek A., Kelley J.M., Weidman J.F.,
RA   Phillips C.A., Spriggs T., Hedblom E., Cotton M.D., Utterback T.R.,
RA   Hanna M.C., Nguyen D.T., Saudek D.M., Brandon R.C., Fine L.D.,
RA   Fritchman J.L., Fuhrmann J.L., Geoghagen N.S.M., Gnehm C.L., McDonald L.A.,
RA   Small K.V., Fraser C.M., Smith H.O., Venter J.C.;
RT   "Whole-genome random sequencing and assembly of Haemophilus influenzae
RT   Rd.";
RL   Science 269:496-512(1995).
RN   [2]
RP   IDENTIFICATION BY MASS SPECTROMETRY.
RC   STRAIN=ATCC 51907 / DSM 11121 / KW20 / Rd;
RX   PubMed=10675023;
RX   DOI=10.1002/(sici)1522-2683(20000101)21:2<411::aid-elps411>3.0.co;2-4;
RA   Langen H., Takacs B., Evers S., Berndt P., Lahm H.W., Wipf B., Gray C.,
RA   Fountoulakis M.;
RT   "Two-dimensional map of the proteome of Haemophilus influenzae.";
RL   Electrophoresis 21:411-429(2000).
CC   -!- FUNCTION: Genetic data indicate it may be involved in ribosome assembly
CC       or function. {ECO:0000250|UniProtKB:A0A0H2VBH0}.
CC   -!- SIMILARITY: Belongs to the ABC transporter superfamily. ABCF family.
CC       YheS subfamily. {ECO:0000305}.
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DR   EMBL; L42023; AAC22317.1; -; Genomic_DNA.
DR   PIR; C64156; C64156.
DR   RefSeq; NP_438818.1; NC_000907.1.
DR   RefSeq; WP_005694483.1; NC_000907.1.
DR   AlphaFoldDB; P44808; -.
DR   SMR; P44808; -.
DR   STRING; 71421.HI_0658; -.
DR   EnsemblBacteria; AAC22317; AAC22317; HI_0658.
DR   KEGG; hin:HI_0658; -.
DR   PATRIC; fig|71421.8.peg.687; -.
DR   eggNOG; COG0488; Bacteria.
DR   HOGENOM; CLU_000604_36_0_6; -.
DR   OMA; CTHIADI; -.
DR   PhylomeDB; P44808; -.
DR   BioCyc; HINF71421:G1GJ1-693-MON; -.
DR   Proteomes; UP000000579; Chromosome.
DR   GO; GO:0005524; F:ATP binding; IBA:GO_Central.
DR   Gene3D; 3.40.50.300; -; 2.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR032781; ABC_tran_Xtn.
DR   InterPro; IPR003439; ABC_transporter-like_ATP-bd.
DR   InterPro; IPR017871; ABC_transporter-like_CS.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   Pfam; PF00005; ABC_tran; 2.
DR   Pfam; PF12848; ABC_tran_Xtn; 1.
DR   SMART; SM00382; AAA; 2.
DR   SUPFAM; SSF52540; SSF52540; 2.
DR   PROSITE; PS00211; ABC_TRANSPORTER_1; 2.
DR   PROSITE; PS50893; ABC_TRANSPORTER_2; 2.
PE   1: Evidence at protein level;
KW   ATP-binding; Nucleotide-binding; Reference proteome; Repeat.
FT   CHAIN           1..638
FT                   /note="Probable ATP-binding protein YheS"
FT                   /id="PRO_0000093189"
FT   DOMAIN          2..246
FT                   /note="ABC transporter 1"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00434"
FT   DOMAIN          313..531
FT                   /note="ABC transporter 2"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00434"
FT   REGION          525..563
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        535..563
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   BINDING         34..41
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /ligand_label="1"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00434"
FT   BINDING         349..356
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /ligand_label="2"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00434"
SQ   SEQUENCE   638 AA;  72231 MW;  D04082E4ACB60099 CRC64;
     MIIFSNLSLK RGQTELLENA SATINPKQKV GLVGKNGCGK SSLFALLKKE LMPEGGEVNY
     PANWRVSWVN QETPALDISA IDYVIQGDRE YCRLQQKLER ANERNDGNAI ARIHGQLETL
     DAWTIQSRAA SLLHGLGFSQ EETIQPVKAF SGGWRMRLNL AQALLCPSDL LLLDEPTNHL
     DLDAVIWLER WLVQYQGTLV LISHDRDFLD PIVTKILHIE NQKLNEYTGD YSSFEVQRAT
     KLAQQTAMYR QQQQKISHLQ KYIDRFKAKA TKAKQAQSRM KALERMELIA PAYVDNPFTF
     EFRPPQSLPN PLVMIEQASA GYGIGESAVE ILSKIKLNLV PGSRIGLLGK NGAGKSTLIK
     LLAGELTALS GTVQLAKGVQ LGYFAQHQLD TLRADESALW HMQKLAPEQT EQQVRDYLGS
     FAFHGDKVNQ AVKSFSGGEK ARLVLALIVW QRPNLLLLDE PTNHLDLDMR QALTEALVDY
     EGSLVVVSHD RHLLRNTVEE FYLVHDKKVE EFKGDLEDYQ KWLSEQNSTS ENKVSEKVGD
     NENSVQNRKE QKRREAELRQ QTAPLRKKIT QLEEKMNKFS SELANIENQL ADTELYNAEN
     KEKLTALLAQ QVDVKKALDD VETEWMTAQE ELEEMLQA