ID   YHET_ECOLI              Reviewed;         340 AA.
AC   P45524; Q2M719;
DT   01-NOV-1995, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1995, sequence version 1.
DT   03-AUG-2022, entry version 139.
DE   RecName: Full=Putative esterase YheT;
DE            EC=3.1.1.-;
GN   Name=yheT; OrderedLocusNames=b3353, JW3316;
OS   Escherichia coli (strain K12).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Escherichia.
OX   NCBI_TaxID=83333;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=K12 / MG1655 / ATCC 47076;
RX   PubMed=9278503; DOI=10.1126/science.277.5331.1453;
RA   Blattner F.R., Plunkett G. III, Bloch C.A., Perna N.T., Burland V.,
RA   Riley M., Collado-Vides J., Glasner J.D., Rode C.K., Mayhew G.F.,
RA   Gregor J., Davis N.W., Kirkpatrick H.A., Goeden M.A., Rose D.J., Mau B.,
RA   Shao Y.;
RT   "The complete genome sequence of Escherichia coli K-12.";
RL   Science 277:1453-1462(1997).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=K12 / W3110 / ATCC 27325 / DSM 5911;
RX   PubMed=16738553; DOI=10.1038/msb4100049;
RA   Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S.,
RA   Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.;
RT   "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655
RT   and W3110.";
RL   Mol. Syst. Biol. 2:E1-E5(2006).
CC   -!- SIMILARITY: Belongs to the AB hydrolase superfamily. AB hydrolase 4
CC       family. {ECO:0000305}.
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DR   EMBL; U18997; AAA58150.1; -; Genomic_DNA.
DR   EMBL; U00096; AAC76378.1; -; Genomic_DNA.
DR   EMBL; AP009048; BAE77937.1; -; Genomic_DNA.
DR   PIR; D65129; D65129.
DR   RefSeq; NP_417812.1; NC_000913.3.
DR   RefSeq; WP_000057356.1; NZ_SSZK01000008.1.
DR   AlphaFoldDB; P45524; -.
DR   BioGRID; 4262473; 16.
DR   IntAct; P45524; 2.
DR   STRING; 511145.b3353; -.
DR   ESTHER; ecoli-yhet; abh_upf0017.
DR   MEROPS; S33.A46; -.
DR   PaxDb; P45524; -.
DR   PRIDE; P45524; -.
DR   EnsemblBacteria; AAC76378; AAC76378; b3353.
DR   EnsemblBacteria; BAE77937; BAE77937; BAE77937.
DR   GeneID; 947855; -.
DR   KEGG; ecj:JW3316; -.
DR   KEGG; eco:b3353; -.
DR   PATRIC; fig|1411691.4.peg.3377; -.
DR   EchoBASE; EB2741; -.
DR   eggNOG; COG0429; Bacteria.
DR   HOGENOM; CLU_032487_0_0_6; -.
DR   InParanoid; P45524; -.
DR   OMA; RNDPFVP; -.
DR   PhylomeDB; P45524; -.
DR   BioCyc; EcoCyc:G7718-MON; -.
DR   PRO; PR:P45524; -.
DR   Proteomes; UP000000318; Chromosome.
DR   Proteomes; UP000000625; Chromosome.
DR   GO; GO:0008126; F:acetylesterase activity; IBA:GO_Central.
DR   GO; GO:0047372; F:acylglycerol lipase activity; IBA:GO_Central.
DR   GO; GO:0050526; F:poly(3-hydroxybutyrate) depolymerase activity; ISM:EcoliWiki.
DR   GO; GO:0034338; F:short-chain carboxylesterase activity; IBA:GO_Central.
DR   GO; GO:0044255; P:cellular lipid metabolic process; IBA:GO_Central.
DR   GO; GO:0051792; P:medium-chain fatty acid biosynthetic process; IBA:GO_Central.
DR   GO; GO:0051793; P:medium-chain fatty acid catabolic process; IBA:GO_Central.
DR   Gene3D; 3.40.50.1820; -; 1.
DR   InterPro; IPR029058; AB_hydrolase.
DR   InterPro; IPR000073; AB_hydrolase_1.
DR   InterPro; IPR000952; AB_hydrolase_4_CS.
DR   InterPro; IPR012020; ABHD4.
DR   Pfam; PF00561; Abhydrolase_1; 1.
DR   PIRSF; PIRSF005211; Ab_hydro_YheT; 1.
DR   SUPFAM; SSF53474; SSF53474; 1.
DR   PROSITE; PS01133; UPF0017; 1.
PE   3: Inferred from homology;
KW   Hydrolase; Reference proteome; Serine esterase.
FT   CHAIN           1..340
FT                   /note="Putative esterase YheT"
FT                   /id="PRO_0000212461"
FT   DOMAIN          73..312
FT                   /note="AB hydrolase-1"
FT                   /evidence="ECO:0000255"
FT   ACT_SITE        153
FT                   /note="Charge relay system"
FT                   /evidence="ECO:0000250"
FT   ACT_SITE        280
FT                   /note="Charge relay system"
FT                   /evidence="ECO:0000250"
FT   ACT_SITE        308
FT                   /note="Charge relay system"
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   340 AA;  38495 MW;  7DB6BA6795CBA64D CRC64;
     MAQITTTDAN EFSSSAEFIP MRGFSNCHLQ TMLPRLFRRQ VKFTPYWQRL ELPDGDFVDL
     AWSENPAQAQ HKPRLVVFHG LEGSLNSPYA HGLVEAAQKR GWLGVVMHFR GCSGEPNRMH
     RIYHSGETED ASWFLRWLQR EFGHAPTAAV GYSLGGNMLA CLLAKEGNDL PVDAAVIVSA
     PFMLEACSYH MEKGFSRVYQ RYLLNLLKAN AARKLAAYPG TLPINLAQLK SVRRIREFDD
     LITARIHGYA DAIDYYRQCS AMPMLNRIAK PTLIIHAKDD PFMDHQVIPK PESLPPQVEY
     QLTEHGGHVG FIGGTLLHPQ MWLESRIPDW LTTYLEAKSC