ID   YHFK_BACSU              Reviewed;         214 AA.
AC   O07609; Q796U0;
DT   20-JAN-2009, integrated into UniProtKB/Swiss-Prot.
DT   01-JUL-1997, sequence version 1.
DT   03-AUG-2022, entry version 109.
DE   RecName: Full=Uncharacterized sugar epimerase YhfK;
DE            EC=4.-.-.-;
GN   Name=yhfK; OrderedLocusNames=BSU10260;
OS   Bacillus subtilis (strain 168).
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Bacillaceae; Bacillus.
OX   NCBI_TaxID=224308;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=168;
RA   Noback M.A., Terpstra P., Holsappel S., Venema G., Bron S.;
RL   Submitted (JUN-1997) to the EMBL/GenBank/DDBJ databases.
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=168;
RX   PubMed=9384377; DOI=10.1038/36786;
RA   Kunst F., Ogasawara N., Moszer I., Albertini A.M., Alloni G., Azevedo V.,
RA   Bertero M.G., Bessieres P., Bolotin A., Borchert S., Borriss R.,
RA   Boursier L., Brans A., Braun M., Brignell S.C., Bron S., Brouillet S.,
RA   Bruschi C.V., Caldwell B., Capuano V., Carter N.M., Choi S.-K.,
RA   Codani J.-J., Connerton I.F., Cummings N.J., Daniel R.A., Denizot F.,
RA   Devine K.M., Duesterhoeft A., Ehrlich S.D., Emmerson P.T., Entian K.-D.,
RA   Errington J., Fabret C., Ferrari E., Foulger D., Fritz C., Fujita M.,
RA   Fujita Y., Fuma S., Galizzi A., Galleron N., Ghim S.-Y., Glaser P.,
RA   Goffeau A., Golightly E.J., Grandi G., Guiseppi G., Guy B.J., Haga K.,
RA   Haiech J., Harwood C.R., Henaut A., Hilbert H., Holsappel S., Hosono S.,
RA   Hullo M.-F., Itaya M., Jones L.-M., Joris B., Karamata D., Kasahara Y.,
RA   Klaerr-Blanchard M., Klein C., Kobayashi Y., Koetter P., Koningstein G.,
RA   Krogh S., Kumano M., Kurita K., Lapidus A., Lardinois S., Lauber J.,
RA   Lazarevic V., Lee S.-M., Levine A., Liu H., Masuda S., Mauel C.,
RA   Medigue C., Medina N., Mellado R.P., Mizuno M., Moestl D., Nakai S.,
RA   Noback M., Noone D., O'Reilly M., Ogawa K., Ogiwara A., Oudega B.,
RA   Park S.-H., Parro V., Pohl T.M., Portetelle D., Porwollik S.,
RA   Prescott A.M., Presecan E., Pujic P., Purnelle B., Rapoport G., Rey M.,
RA   Reynolds S., Rieger M., Rivolta C., Rocha E., Roche B., Rose M., Sadaie Y.,
RA   Sato T., Scanlan E., Schleich S., Schroeter R., Scoffone F., Sekiguchi J.,
RA   Sekowska A., Seror S.J., Serror P., Shin B.-S., Soldo B., Sorokin A.,
RA   Tacconi E., Takagi T., Takahashi H., Takemaru K., Takeuchi M.,
RA   Tamakoshi A., Tanaka T., Terpstra P., Tognoni A., Tosato V., Uchiyama S.,
RA   Vandenbol M., Vannier F., Vassarotti A., Viari A., Wambutt R., Wedler E.,
RA   Wedler H., Weitzenegger T., Winters P., Wipat A., Yamamoto H., Yamane K.,
RA   Yasumoto K., Yata K., Yoshida K., Yoshikawa H.-F., Zumstein E.,
RA   Yoshikawa H., Danchin A.;
RT   "The complete genome sequence of the Gram-positive bacterium Bacillus
RT   subtilis.";
RL   Nature 390:249-256(1997).
RN   [3]
RP   INDUCTION.
RC   STRAIN=168 / JH642;
RX   PubMed=11790741; DOI=10.1128/jb.184.3.718-727.2002;
RA   Hoffmann T., Schuetz A., Brosius M., Voelker A., Voelker U., Bremer E.;
RT   "High-salinity-induced iron limitation in Bacillus subtilis.";
RL   J. Bacteriol. 184:718-727(2002).
CC   -!- INDUCTION: By high salinity. {ECO:0000269|PubMed:11790741}.
CC   -!- SIMILARITY: Belongs to the NAD(P)-dependent epimerase/dehydratase
CC       family. {ECO:0000305}.
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DR   EMBL; Y14083; CAA74532.1; -; Genomic_DNA.
DR   EMBL; AL009126; CAB12866.1; -; Genomic_DNA.
DR   PIR; H69830; H69830.
DR   RefSeq; NP_388907.1; NC_000964.3.
DR   RefSeq; WP_003245344.1; NZ_JNCM01000035.1.
DR   AlphaFoldDB; O07609; -.
DR   SMR; O07609; -.
DR   STRING; 224308.BSU10260; -.
DR   PaxDb; O07609; -.
DR   PRIDE; O07609; -.
DR   DNASU; 936309; -.
DR   EnsemblBacteria; CAB12866; CAB12866; BSU_10260.
DR   GeneID; 936309; -.
DR   KEGG; bsu:BSU10260; -.
DR   PATRIC; fig|224308.179.peg.1102; -.
DR   eggNOG; COG0702; Bacteria.
DR   InParanoid; O07609; -.
DR   OMA; AKHYADR; -.
DR   PhylomeDB; O07609; -.
DR   BioCyc; BSUB:BSU10260-MON; -.
DR   Proteomes; UP000001570; Chromosome.
DR   GO; GO:0016829; F:lyase activity; IEA:UniProtKB-KW.
DR   InterPro; IPR016040; NAD(P)-bd_dom.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   Pfam; PF13460; NAD_binding_10; 1.
DR   SUPFAM; SSF51735; SSF51735; 1.
PE   2: Evidence at transcript level;
KW   Lyase; Reference proteome.
FT   CHAIN           1..214
FT                   /note="Uncharacterized sugar epimerase YhfK"
FT                   /id="PRO_0000360626"
FT   ACT_SITE        129
FT                   /note="Proton acceptor"
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   214 AA;  22760 MW;  7CEB208C5EE2F4B1 CRC64;
     MKVFLIGANG QIGQRLVSLF QDNPDHSIRA MVRKEEQKAS LEAAGAEAVL ANLEGSPEEI
     AAAAKGCDAI IFTAGSGGST GYDKTLLVDL DGAAKAIEAA AIAGIKRFIM VSALQAHNRE
     NWNEALKPYY VAKHYADKIL EASGLTYTII RPGGLRNEPG TGTVSAAKDL ERGFISRDDV
     AKTVIASLDE KNTENRAFDL TEGDTPIAEA LKKL