ID   YHFT_ECOLI              Reviewed;         434 AA.
AC   P45546; Q2M742;
DT   01-NOV-1995, integrated into UniProtKB/Swiss-Prot.
DT   15-JUL-1998, sequence version 2.
DT   03-AUG-2022, entry version 126.
DE   RecName: Full=Uncharacterized protein YhfT;
GN   Name=yhfT; OrderedLocusNames=b3377, JW3340;
OS   Escherichia coli (strain K12).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Escherichia.
OX   NCBI_TaxID=83333;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=K12 / MG1655 / ATCC 47076;
RX   PubMed=9278503; DOI=10.1126/science.277.5331.1453;
RA   Blattner F.R., Plunkett G. III, Bloch C.A., Perna N.T., Burland V.,
RA   Riley M., Collado-Vides J., Glasner J.D., Rode C.K., Mayhew G.F.,
RA   Gregor J., Davis N.W., Kirkpatrick H.A., Goeden M.A., Rose D.J., Mau B.,
RA   Shao Y.;
RT   "The complete genome sequence of Escherichia coli K-12.";
RL   Science 277:1453-1462(1997).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=K12 / W3110 / ATCC 27325 / DSM 5911;
RX   PubMed=16738553; DOI=10.1038/msb4100049;
RA   Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S.,
RA   Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.;
RT   "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655
RT   and W3110.";
RL   Mol. Syst. Biol. 2:E1-E5(2006).
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
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DR   EMBL; U18997; AAA58174.1; ALT_FRAME; Genomic_DNA.
DR   EMBL; U00096; AAC76402.1; -; Genomic_DNA.
DR   EMBL; AP009048; BAE77914.1; -; Genomic_DNA.
DR   PIR; D65132; D65132.
DR   RefSeq; NP_417836.1; NC_000913.3.
DR   RefSeq; WP_000366857.1; NZ_CP014272.1.
DR   AlphaFoldDB; P45546; -.
DR   BioGRID; 4263378; 977.
DR   DIP; DIP-12329N; -.
DR   IntAct; P45546; 1.
DR   STRING; 511145.b3377; -.
DR   TCDB; 9.B.118.1.1; the 11 or 12 tms yhft (yhft) family.
DR   PaxDb; P45546; -.
DR   PRIDE; P45546; -.
DR   EnsemblBacteria; AAC76402; AAC76402; b3377.
DR   EnsemblBacteria; BAE77914; BAE77914; BAE77914.
DR   GeneID; 947883; -.
DR   KEGG; ecj:JW3340; -.
DR   KEGG; eco:b3377; -.
DR   PATRIC; fig|1411691.4.peg.3353; -.
DR   EchoBASE; EB2751; -.
DR   eggNOG; ENOG502Z8E9; Bacteria.
DR   HOGENOM; CLU_051800_0_0_6; -.
DR   OMA; MGEHIRT; -.
DR   BioCyc; EcoCyc:G7729-MON; -.
DR   PRO; PR:P45546; -.
DR   Proteomes; UP000000318; Chromosome.
DR   Proteomes; UP000000625; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IDA:EcoCyc.
DR   InterPro; IPR019733; Uncharacterised_YhfT.
DR   Pfam; PF10797; YhfT; 1.
PE   4: Predicted;
KW   Cell membrane; Membrane; Reference proteome; Transmembrane;
KW   Transmembrane helix.
FT   CHAIN           1..434
FT                   /note="Uncharacterized protein YhfT"
FT                   /id="PRO_0000169529"
FT   TRANSMEM        50..70
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        72..92
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        95..115
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        135..155
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        158..178
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        179..199
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        229..249
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        288..308
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        319..339
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        376..396
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        412..432
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   434 AA;  46516 MW;  8AEE6E009E7A9D14 CRC64;
     MDLYIQIIVV ACLTGMTSLL AHRSAAVFHD GIRPILPQLI EGYMNRREAG SIAFGLSIGF
     VASVGISFTL KTGLLNAWLL FLPTDILGVL AINSLMAFGL GAIWGVLILT CLLPVNQLLT
     ALPVDVLGSL GELSSPVVSA FALFPLVAIF YQFGWKQSLI AAVVVLMTRV VVVRYFPHLN
     PESIEIFIGM VMLLGIAITH DLRHRDENDI DASGLSVFEE RTSRIIKNLP YIAIVGALIA
     AVASMKIFAG SEVSIFTLEK AYSAGVTPEQ SQTLINQAAL AEFMRGLGFV PLIATTALAT
     GVYAVAGFTF VYAVDYLSPN PMVAAVLGAV VISAEVLLLR SIGKWLGRYP SVRNASDNIR
     NAMNMLMEVA LLVGSIFAAI KMAGYTGFSI AVAIYFLNES LGRPVQKMAA PVVAVMITGI
     LLNVLYWLGL FVPA