ID   YHFW_ECOLI              Reviewed;         408 AA.
AC   P45549; Q2M745;
DT   01-NOV-1995, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1995, sequence version 1.
DT   03-AUG-2022, entry version 140.
DE   RecName: Full=Uncharacterized protein YhfW;
GN   Name=yhfW; OrderedLocusNames=b3380, JW3343;
OS   Escherichia coli (strain K12).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Escherichia.
OX   NCBI_TaxID=83333;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=K12 / MG1655 / ATCC 47076;
RX   PubMed=9278503; DOI=10.1126/science.277.5331.1453;
RA   Blattner F.R., Plunkett G. III, Bloch C.A., Perna N.T., Burland V.,
RA   Riley M., Collado-Vides J., Glasner J.D., Rode C.K., Mayhew G.F.,
RA   Gregor J., Davis N.W., Kirkpatrick H.A., Goeden M.A., Rose D.J., Mau B.,
RA   Shao Y.;
RT   "The complete genome sequence of Escherichia coli K-12.";
RL   Science 277:1453-1462(1997).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=K12 / W3110 / ATCC 27325 / DSM 5911;
RX   PubMed=16738553; DOI=10.1038/msb4100049;
RA   Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S.,
RA   Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.;
RT   "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655
RT   and W3110.";
RL   Mol. Syst. Biol. 2:E1-E5(2006).
CC   -!- COFACTOR:
CC       Name=Mn(2+); Xref=ChEBI:CHEBI:29035; Evidence={ECO:0000305};
CC       Note=Binds 1 or 2 manganese ions. {ECO:0000305};
CC   -!- SIMILARITY: Belongs to the phosphopentomutase family. {ECO:0000305}.
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DR   EMBL; U18997; AAA58177.1; -; Genomic_DNA.
DR   EMBL; U00096; AAC76405.1; -; Genomic_DNA.
DR   EMBL; AP009048; BAE77911.1; -; Genomic_DNA.
DR   PIR; G65132; G65132.
DR   RefSeq; NP_417839.1; NC_000913.3.
DR   RefSeq; WP_000090644.1; NZ_LN832404.1.
DR   AlphaFoldDB; P45549; -.
DR   SMR; P45549; -.
DR   BioGRID; 4262082; 69.
DR   BioGRID; 852199; 1.
DR   IntAct; P45549; 2.
DR   STRING; 511145.b3380; -.
DR   PaxDb; P45549; -.
DR   PRIDE; P45549; -.
DR   DNASU; 947890; -.
DR   EnsemblBacteria; AAC76405; AAC76405; b3380.
DR   EnsemblBacteria; BAE77911; BAE77911; BAE77911.
DR   GeneID; 947890; -.
DR   KEGG; ecj:JW3343; -.
DR   KEGG; eco:b3380; -.
DR   PATRIC; fig|1411691.4.peg.3350; -.
DR   EchoBASE; EB2754; -.
DR   eggNOG; COG1015; Bacteria.
DR   HOGENOM; CLU_053861_1_0_6; -.
DR   InParanoid; P45549; -.
DR   OMA; HQEIMGT; -.
DR   PhylomeDB; P45549; -.
DR   BioCyc; EcoCyc:G7732-MON; -.
DR   PRO; PR:P45549; -.
DR   Proteomes; UP000000318; Chromosome.
DR   Proteomes; UP000000625; Chromosome.
DR   GO; GO:0005829; C:cytosol; IBA:GO_Central.
DR   GO; GO:0000287; F:magnesium ion binding; IEA:InterPro.
DR   GO; GO:0008973; F:phosphopentomutase activity; IBA:GO_Central.
DR   GO; GO:0043094; P:cellular metabolic compound salvage; IEA:InterPro.
DR   GO; GO:0009117; P:nucleotide metabolic process; IEA:InterPro.
DR   CDD; cd16009; PPM; 1.
DR   Gene3D; 3.30.70.1250; -; 1.
DR   Gene3D; 3.40.720.10; -; 1.
DR   InterPro; IPR017850; Alkaline_phosphatase_core_sf.
DR   InterPro; IPR010045; DeoB.
DR   InterPro; IPR006124; Metalloenzyme.
DR   InterPro; IPR024052; Phosphopentomutase_DeoB_cap_sf.
DR   PANTHER; PTHR21110; PTHR21110; 1.
DR   Pfam; PF01676; Metalloenzyme; 1.
DR   PIRSF; PIRSF001491; Ppentomutase; 1.
DR   SUPFAM; SSF53649; SSF53649; 1.
PE   3: Inferred from homology;
KW   Manganese; Metal-binding; Reference proteome.
FT   CHAIN           1..408
FT                   /note="Uncharacterized protein YhfW"
FT                   /id="PRO_0000199866"
FT   BINDING         10
FT                   /ligand="Mn(2+)"
FT                   /ligand_id="ChEBI:CHEBI:29035"
FT                   /evidence="ECO:0000250"
FT   BINDING         302
FT                   /ligand="Mn(2+)"
FT                   /ligand_id="ChEBI:CHEBI:29035"
FT                   /evidence="ECO:0000250"
FT   BINDING         338
FT                   /ligand="Mn(2+)"
FT                   /ligand_id="ChEBI:CHEBI:29035"
FT                   /evidence="ECO:0000250"
FT   BINDING         339
FT                   /ligand="Mn(2+)"
FT                   /ligand_id="ChEBI:CHEBI:29035"
FT                   /evidence="ECO:0000250"
FT   BINDING         350
FT                   /ligand="Mn(2+)"
FT                   /ligand_id="ChEBI:CHEBI:29035"
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   408 AA;  44560 MW;  147CBB78F99AF8C7 CRC64;
     MARFVVLVID SFGVGAMKDV TLVRPQDAGA NTCGHILSQL PHLQLPTLET LGLINALGYA
     PGDMQPSDSA TWGVAELQHE GGDTFMGHQE ILGTRPLPPL RMPFRDVIDR VEQALVSAGW
     QVERRGDDLQ FLWVNQAVAI GDNLEADLGQ VYNITANLSV ISFDDAIKIG RIVREQVQVG
     RVITFGGLLT DSQRILDAAE SKEGRFIGIN APRSGAYDNG FQVVHMGYGV DEKVQVPQKL
     YEAGVPTVLV GKVADIVNNP YGVSWQNLVD SQRIMDITLN EFNTHPTAFI CTNIQETDLA
     GHAEDVARYA ERLQVVDRNL ARLVEAMQPD DCLVVMADHG NDPTIGHSHH TREVVPVLVY
     QQGMIATQLG VRTTLSDVGA TVCEFFRAPP PQNGRSFLSS LRFAGDTL