YHG6_SCHPO
ID YHG6_SCHPO Reviewed; 466 AA.
AC Q9P6I4;
DT 31-AUG-2004, integrated into UniProtKB/Swiss-Prot.
DT 01-OCT-2000, sequence version 1.
DT 25-MAY-2022, entry version 110.
DE RecName: Full=Putative mannan endo-1,6-alpha-mannosidase C1198.06c;
DE EC=3.2.1.101;
DE AltName: Full=Endo-alpha-1->6-D-mannanase C1198.06c;
DE Flags: Precursor;
GN ORFNames=SPBC1198.06c;
OS Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina;
OC Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae;
OC Schizosaccharomyces.
OX NCBI_TaxID=284812;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=972 / ATCC 24843;
RX PubMed=11859360; DOI=10.1038/nature724;
RA Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A.,
RA Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S.,
RA Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M.,
RA Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S.,
RA Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S.,
RA Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D.,
RA Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P.,
RA Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K.,
RA O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M.,
RA Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N.,
RA Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A.,
RA Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R.,
RA Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M.,
RA Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A.,
RA Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A.,
RA Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H.,
RA Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S.,
RA Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C.,
RA Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A.,
RA Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M.,
RA del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S.,
RA Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R.,
RA Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G.,
RA Nurse P.;
RT "The genome sequence of Schizosaccharomyces pombe.";
RL Nature 415:871-880(2002).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=Random hydrolysis of (1->6)-alpha-D-mannosidic linkages in
CC unbranched (1->6)-mannans.; EC=3.2.1.101;
CC -!- SIMILARITY: Belongs to the glycosyl hydrolase 76 family. {ECO:0000305}.
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DR EMBL; CU329671; CAB91181.1; -; Genomic_DNA.
DR RefSeq; NP_595075.1; NM_001020981.2.
DR AlphaFoldDB; Q9P6I4; -.
DR SMR; Q9P6I4; -.
DR BioGRID; 276488; 15.
DR STRING; 4896.SPBC1198.06c.1; -.
DR CAZy; GH76; Glycoside Hydrolase Family 76.
DR PaxDb; Q9P6I4; -.
DR EnsemblFungi; SPBC1198.06c.1; SPBC1198.06c.1:pep; SPBC1198.06c.
DR GeneID; 2539944; -.
DR KEGG; spo:SPBC1198.06c; -.
DR PomBase; SPBC1198.06c; -.
DR VEuPathDB; FungiDB:SPBC1198.06c; -.
DR eggNOG; ENOG502QSWP; Eukaryota.
DR HOGENOM; CLU_025694_1_2_1; -.
DR InParanoid; Q9P6I4; -.
DR OMA; YMGNDDQ; -.
DR PhylomeDB; Q9P6I4; -.
DR PRO; PR:Q9P6I4; -.
DR Proteomes; UP000002485; Chromosome II.
DR GO; GO:0031362; C:anchored component of external side of plasma membrane; ISO:PomBase.
DR GO; GO:0005783; C:endoplasmic reticulum; HDA:PomBase.
DR GO; GO:0008496; F:mannan endo-1,6-alpha-mannosidase activity; ISM:PomBase.
DR GO; GO:0051692; P:cellular oligosaccharide catabolic process; IC:PomBase.
DR GO; GO:0009272; P:fungal-type cell wall biogenesis; ISO:PomBase.
DR InterPro; IPR008928; 6-hairpin_glycosidase_sf.
DR InterPro; IPR005198; Glyco_hydro_76.
DR InterPro; IPR014480; Mannan-1_6-alpha_mannosidase.
DR PANTHER; PTHR12145; PTHR12145; 1.
DR Pfam; PF03663; Glyco_hydro_76; 1.
DR PIRSF; PIRSF016302; Man_a_manosd; 1.
DR SUPFAM; SSF48208; SSF48208; 1.
PE 3: Inferred from homology;
KW Glycoprotein; Glycosidase; Hydrolase; Reference proteome; Signal.
FT SIGNAL 1..20
FT /evidence="ECO:0000255"
FT CHAIN 21..466
FT /note="Putative mannan endo-1,6-alpha-mannosidase
FT C1198.06c"
FT /id="PRO_0000012129"
FT CARBOHYD 47
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 77
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 131
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 195
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 217
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 232
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 257
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 357
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 396
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 399
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 409
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 412
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
SQ SEQUENCE 466 AA; 52039 MW; 41CE1E22BD616BF6 CRC64;
MNIYSVGLFY FFLVFIGAQA MDLDITDYQS IDNTVNIMMK DLMNYWNASS QAFVASYWWV
TGATMGALLY NYELFNNDTY VDLISSSLLY NAGSGFDYQP SFEYFNLGND DQGMWAAAAM
DAAEANFSPP NSTEHSWLEL TQAAFNRMSG RWDSSTCGGG LRWQAFAWLN GYSYKASVSN
ALLFQLSSRL ARFTNESVYS DWANKIWDWT TDVGFVNTTT YAVYDGADTS TNCTTLDPSQ
WSYNIGIFMV GAAYMYNYTG ETVWRERLDG LISHATSYFF TDDIAWDPQC EYFDDCNSDQ
TAFKGIFMQS FGNTIRLAPY TYDTLYPLIQ TSAAAAAKQC CGGYSGTSCG IYWFWNNGTW
DDNYGVQEQF SALQAVQMLM IEYAPEIATL ASSTDNRSNS TYASNVVIND TNTTTTIVVK
EKDRGGAGFL TFLSAIFILG ASIWALVEDE EGKIPSRGKK GIAISS
