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YHGE_BACSU
ID   YHGE_BACSU              Reviewed;         775 AA.
AC   P32399;
DT   01-OCT-1993, integrated into UniProtKB/Swiss-Prot.
DT   15-JUL-1998, sequence version 2.
DT   03-AUG-2022, entry version 128.
DE   RecName: Full=Uncharacterized protein YhgE;
DE   AltName: Full=ORFB;
GN   Name=yhgE; Synonyms=yixE; OrderedLocusNames=BSU10160;
OS   Bacillus subtilis (strain 168).
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Bacillaceae; Bacillus.
OX   NCBI_TaxID=224308;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=168;
RX   PubMed=9579061; DOI=10.1099/00221287-144-4-859;
RA   Noback M.A., Holsappel S., Kiewiet R., Terpstra P., Wambutt R., Wedler H.,
RA   Venema G., Bron S.;
RT   "The 172 kb prkA-addAB region from 83 degrees to 97 degrees of the Bacillus
RT   subtilis chromosome contains several dysfunctional genes, the glyB marker,
RT   many genes encoding transporter proteins, and the ubiquitous hit gene.";
RL   Microbiology 144:859-875(1998).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=168;
RX   PubMed=9384377; DOI=10.1038/36786;
RA   Kunst F., Ogasawara N., Moszer I., Albertini A.M., Alloni G., Azevedo V.,
RA   Bertero M.G., Bessieres P., Bolotin A., Borchert S., Borriss R.,
RA   Boursier L., Brans A., Braun M., Brignell S.C., Bron S., Brouillet S.,
RA   Bruschi C.V., Caldwell B., Capuano V., Carter N.M., Choi S.-K.,
RA   Codani J.-J., Connerton I.F., Cummings N.J., Daniel R.A., Denizot F.,
RA   Devine K.M., Duesterhoeft A., Ehrlich S.D., Emmerson P.T., Entian K.-D.,
RA   Errington J., Fabret C., Ferrari E., Foulger D., Fritz C., Fujita M.,
RA   Fujita Y., Fuma S., Galizzi A., Galleron N., Ghim S.-Y., Glaser P.,
RA   Goffeau A., Golightly E.J., Grandi G., Guiseppi G., Guy B.J., Haga K.,
RA   Haiech J., Harwood C.R., Henaut A., Hilbert H., Holsappel S., Hosono S.,
RA   Hullo M.-F., Itaya M., Jones L.-M., Joris B., Karamata D., Kasahara Y.,
RA   Klaerr-Blanchard M., Klein C., Kobayashi Y., Koetter P., Koningstein G.,
RA   Krogh S., Kumano M., Kurita K., Lapidus A., Lardinois S., Lauber J.,
RA   Lazarevic V., Lee S.-M., Levine A., Liu H., Masuda S., Mauel C.,
RA   Medigue C., Medina N., Mellado R.P., Mizuno M., Moestl D., Nakai S.,
RA   Noback M., Noone D., O'Reilly M., Ogawa K., Ogiwara A., Oudega B.,
RA   Park S.-H., Parro V., Pohl T.M., Portetelle D., Porwollik S.,
RA   Prescott A.M., Presecan E., Pujic P., Purnelle B., Rapoport G., Rey M.,
RA   Reynolds S., Rieger M., Rivolta C., Rocha E., Roche B., Rose M., Sadaie Y.,
RA   Sato T., Scanlan E., Schleich S., Schroeter R., Scoffone F., Sekiguchi J.,
RA   Sekowska A., Seror S.J., Serror P., Shin B.-S., Soldo B., Sorokin A.,
RA   Tacconi E., Takagi T., Takahashi H., Takemaru K., Takeuchi M.,
RA   Tamakoshi A., Tanaka T., Terpstra P., Tognoni A., Tosato V., Uchiyama S.,
RA   Vandenbol M., Vannier F., Vassarotti A., Viari A., Wambutt R., Wedler E.,
RA   Wedler H., Weitzenegger T., Winters P., Wipat A., Yamamoto H., Yamane K.,
RA   Yasumoto K., Yata K., Yoshida K., Yoshikawa H.-F., Zumstein E.,
RA   Yoshikawa H., Danchin A.;
RT   "The complete genome sequence of the Gram-positive bacterium Bacillus
RT   subtilis.";
RL   Nature 390:249-256(1997).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-145.
RX   PubMed=1459957; DOI=10.1128/jb.174.24.8081-8093.1992;
RA   Hansson M., Hederstedt L.;
RT   "Cloning and characterization of the Bacillus subtilis hemEHY gene cluster,
RT   which encodes protoheme IX biosynthetic enzymes.";
RL   J. Bacteriol. 174:8081-8093(1992).
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: To L.lactis phage infection protein (PIP). {ECO:0000305}.
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DR   EMBL; Y14083; CAA74522.1; -; Genomic_DNA.
DR   EMBL; AL009126; CAB12856.1; -; Genomic_DNA.
DR   EMBL; M97208; AAA22521.1; -; Genomic_DNA.
DR   PIR; H69832; H69832.
DR   RefSeq; NP_388897.1; NC_000964.3.
DR   RefSeq; WP_003245424.1; NZ_JNCM01000035.1.
DR   AlphaFoldDB; P32399; -.
DR   IntAct; P32399; 37.
DR   STRING; 224308.BSU10160; -.
DR   TCDB; 3.A.1.155.3; the atp-binding cassette (abc) superfamily.
DR   PaxDb; P32399; -.
DR   PRIDE; P32399; -.
DR   EnsemblBacteria; CAB12856; CAB12856; BSU_10160.
DR   GeneID; 936303; -.
DR   KEGG; bsu:BSU10160; -.
DR   PATRIC; fig|224308.179.peg.1092; -.
DR   eggNOG; COG1511; Bacteria.
DR   InParanoid; P32399; -.
DR   OMA; MQIGIGK; -.
DR   PhylomeDB; P32399; -.
DR   BioCyc; BSUB:BSU10160-MON; -.
DR   Proteomes; UP000001570; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   InterPro; IPR017501; Phage_infect_YhgE_C.
DR   InterPro; IPR017500; Phage_infect_YhgE_N.
DR   InterPro; IPR023908; xxxLxxG_rpt.
DR   TIGRFAMs; TIGR03062; pip_yhgE_Cterm; 1.
DR   TIGRFAMs; TIGR03061; pip_yhgE_Nterm; 1.
DR   TIGRFAMs; TIGR03057; xxxLxxG_by_4; 1.
PE   4: Predicted;
KW   Cell membrane; Membrane; Reference proteome; Transmembrane;
KW   Transmembrane helix.
FT   CHAIN           1..775
FT                   /note="Uncharacterized protein YhgE"
FT                   /id="PRO_0000049579"
FT   TRANSMEM        16..36
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        585..605
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        625..645
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        655..675
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        742..762
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   775 AA;  84094 MW;  49A5AAC8A6A70B66 CRC64;
     MNTIRSQWKD IVTSKKLLIP IIAILFVPLI YSGVFLKAYW DPYGTVDQLP VVVVNQDKGA
     TYEGEKLQIG DDLVKELKDN NNFDWHFSND LDQSLKDLLN QKYYLVVEIP EDFSKNASTV
     LDKNPKKLDL KYHTNAGSNY VGATIGEKAI DKLKASVSKE VTEQYTKVIF DNFKDIAKGL
     SDASSGAKKI DDGTKDAKNG SAQLKENLAK LKESTATISD KTAQLADGAA QVTSGIQSLD
     SSLGKFQDSS NQIYDKSSQL AAGSGELTSK MNELLAGLQN VQKGTPNLTN GLDQLNSKVQ
     EGSEKAAKAE KIINALDLTK LETAVNNLEK SETAMKEFKK QLTDFENSLK NRDQAFKNVI
     NSSDFLTAEQ KSQLINSVEK KLPQVDAPDF DQILSQLPTA DQLPDIATIK SSLEDVKAQV
     AQVKAMPEAT SKLYNGAKTI QDAIDRLTEG ADKIYNGSQK LTDGQTKLTA GIGEYNKQFA
     KAKAGSEQLV TGSSQVSGGL FKLLDGSKQV QSGSSKLADG SASLDTGLGK LLDGTGELSS
     KLKDAADQTG DIDADDQTYG MFADPVKTKD DAIHSVPNYG TGLTPYILSM GLYVGGIMLT
     VVFPLKEASG RPRNGFEWFF SKFNVMMLVG IIQSLIVATV LLLGIGLEVE STWRFYVFTI
     ITSLAFLAII QFLATTMGNP GRFIAVIILV LQLGASGGTF PLELLPNFYQ VIHGALPMTY
     SINGFRAVIS NGDFGYMWQM AGVLIGIALV MIALSITYFT MLSRKEETSE EQPAS
 
 
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