ID   YHGE_ECOLI              Reviewed;         574 AA.
AC   P45804; Q2M767;
DT   01-NOV-1995, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1995, sequence version 1.
DT   03-AUG-2022, entry version 129.
DE   RecName: Full=Uncharacterized protein YhgE;
GN   Name=yhgE; OrderedLocusNames=b3402, JW3365;
OS   Escherichia coli (strain K12).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Escherichia.
OX   NCBI_TaxID=83333;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=K12 / MG1655 / ATCC 47076;
RX   PubMed=9278503; DOI=10.1126/science.277.5331.1453;
RA   Blattner F.R., Plunkett G. III, Bloch C.A., Perna N.T., Burland V.,
RA   Riley M., Collado-Vides J., Glasner J.D., Rode C.K., Mayhew G.F.,
RA   Gregor J., Davis N.W., Kirkpatrick H.A., Goeden M.A., Rose D.J., Mau B.,
RA   Shao Y.;
RT   "The complete genome sequence of Escherichia coli K-12.";
RL   Science 277:1453-1462(1997).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=K12 / W3110 / ATCC 27325 / DSM 5911;
RX   PubMed=16738553; DOI=10.1038/msb4100049;
RA   Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S.,
RA   Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.;
RT   "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655
RT   and W3110.";
RL   Mol. Syst. Biol. 2:E1-E5(2006).
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: To B.subtilis YrdB. {ECO:0000305}.
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DR   EMBL; U18997; AAA58199.1; -; Genomic_DNA.
DR   EMBL; U00096; AAC76427.1; -; Genomic_DNA.
DR   EMBL; AP009048; BAE77889.1; -; Genomic_DNA.
DR   PIR; E65135; E65135.
DR   RefSeq; NP_417861.1; NC_000913.3.
DR   RefSeq; WP_000370879.1; NZ_SSZK01000008.1.
DR   AlphaFoldDB; P45804; -.
DR   BioGRID; 4262483; 132.
DR   IntAct; P45804; 1.
DR   STRING; 511145.b3402; -.
DR   TCDB; 9.B.65.1.1; the putative transporter (yhge) family.
DR   PaxDb; P45804; -.
DR   PRIDE; P45804; -.
DR   EnsemblBacteria; AAC76427; AAC76427; b3402.
DR   EnsemblBacteria; BAE77889; BAE77889; BAE77889.
DR   GeneID; 947651; -.
DR   KEGG; ecj:JW3365; -.
DR   KEGG; eco:b3402; -.
DR   PATRIC; fig|1411691.4.peg.3328; -.
DR   EchoBASE; EB2767; -.
DR   eggNOG; COG3449; Bacteria.
DR   HOGENOM; CLU_030637_1_1_6; -.
DR   OMA; WALWLRI; -.
DR   PhylomeDB; P45804; -.
DR   BioCyc; EcoCyc:G7745-MON; -.
DR   PRO; PR:P45804; -.
DR   Proteomes; UP000000318; Chromosome.
DR   Proteomes; UP000000625; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IDA:EcoCyc.
DR   InterPro; IPR025291; DUF4153.
DR   Pfam; PF13687; DUF4153; 1.
PE   4: Predicted;
KW   Cell membrane; Membrane; Reference proteome; Transmembrane;
KW   Transmembrane helix.
FT   CHAIN           1..574
FT                   /note="Uncharacterized protein YhgE"
FT                   /id="PRO_0000169545"
FT   TRANSMEM        12..32
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        39..59
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        66..86
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        99..119
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        142..162
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        178..198
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        214..234
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        248..268
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        286..306
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        320..340
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        353..373
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   574 AA;  64637 MW;  529E33C38D5BEF59 CRC64;
     MDNVELSPAT RWGMIATGLL QGLVCYLLIA WLSGKNHSWI VYGVPATVAF SSVLLFSVIS
     FKQKRLWGWL ALVFIATLGM SGWLKWQTDG MNPWRAEKAL WDFGCYLLLM AMLLLPWIQQ
     SLRIRNDSSR YRYFYQSVWH NVLILLVIFL ANGLTWLVLL LWSELFKLVG ITFFNTLFFA
     TDWFIYLTLG LVTALAVILA RTQSRLIDSI QKLFTLIATG LLPLVSLLTL MFIITLPFTG
     LSAISRHISA AGLLLTLAFL QLILMAIVRD PQKASLPWTG PLRCLIKTAL LVAPLYVFVA
     AWALWLRVAQ YGWTVDRLQG VLAVLVLLVW SLGYFVSIVW RKGQNPVVLQ GKVNLAVSLL
     VLVILVLLNS PVLDSMRISV NSHMARYQSG KNTSDQVTIY MLEQSGRYGR AALESLKSDA
     GFMKDPKRAR DLLMALDGEQ HLQQQVSEKV LADNVLIAPG SVKPDATFWS ALIQDRYNVM
     TCIEKDACVL VEQDLNSDGQ AERILFAFND DRVIVYGFDS DRKEWDALDM SLLPNEITKE
     KLLTAAKDGK LGTKPKAWRD LVVDGERLNV NLNE