YHHX_ECOLI
ID YHHX_ECOLI Reviewed; 345 AA.
AC P46853; Q2M7A3;
DT 01-NOV-1995, integrated into UniProtKB/Swiss-Prot.
DT 01-NOV-1995, sequence version 1.
DT 03-AUG-2022, entry version 135.
DE RecName: Full=Uncharacterized oxidoreductase YhhX;
DE EC=1.-.-.-;
GN Name=yhhX; OrderedLocusNames=b3440, JW3403;
OS Escherichia coli (strain K12).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Escherichia.
OX NCBI_TaxID=83333;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=K12 / MG1655 / ATCC 47076;
RX PubMed=9278503; DOI=10.1126/science.277.5331.1453;
RA Blattner F.R., Plunkett G. III, Bloch C.A., Perna N.T., Burland V.,
RA Riley M., Collado-Vides J., Glasner J.D., Rode C.K., Mayhew G.F.,
RA Gregor J., Davis N.W., Kirkpatrick H.A., Goeden M.A., Rose D.J., Mau B.,
RA Shao Y.;
RT "The complete genome sequence of Escherichia coli K-12.";
RL Science 277:1453-1462(1997).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=K12 / W3110 / ATCC 27325 / DSM 5911;
RX PubMed=16738553; DOI=10.1038/msb4100049;
RA Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S.,
RA Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.;
RT "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655
RT and W3110.";
RL Mol. Syst. Biol. 2:E1-E5(2006).
RN [3]
RP IDENTIFICATION BY MASS SPECTROMETRY.
RC STRAIN=B / BL21;
RX PubMed=10493123;
RX DOI=10.1002/(sici)1522-2683(19990801)20:11<2181::aid-elps2181>3.0.co;2-q;
RA Fountoulakis M., Takacs M.-F., Berndt P., Langen H., Takacs B.;
RT "Enrichment of low abundance proteins of Escherichia coli by hydroxyapatite
RT chromatography.";
RL Electrophoresis 20:2181-2195(1999).
CC -!- SIMILARITY: Belongs to the Gfo/Idh/MocA family. Biliverdin reductase
CC subfamily. {ECO:0000305}.
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DR EMBL; U18997; AAA58238.1; -; Genomic_DNA.
DR EMBL; U00096; AAC76465.1; -; Genomic_DNA.
DR EMBL; AP009048; BAE77853.1; -; Genomic_DNA.
DR PIR; C65140; C65140.
DR RefSeq; NP_417897.1; NC_000913.3.
DR RefSeq; WP_000236293.1; NZ_SSZK01000008.1.
DR PDB; 3F4L; X-ray; 2.00 A; A/B/C/D/E/F=1-345.
DR PDBsum; 3F4L; -.
DR AlphaFoldDB; P46853; -.
DR SMR; P46853; -.
DR BioGRID; 4262488; 21.
DR DIP; DIP-12357N; -.
DR IntAct; P46853; 21.
DR STRING; 511145.b3440; -.
DR jPOST; P46853; -.
DR PaxDb; P46853; -.
DR PRIDE; P46853; -.
DR EnsemblBacteria; AAC76465; AAC76465; b3440.
DR EnsemblBacteria; BAE77853; BAE77853; BAE77853.
DR GeneID; 66672677; -.
DR GeneID; 947944; -.
DR KEGG; ecj:JW3403; -.
DR KEGG; eco:b3440; -.
DR PATRIC; fig|1411691.4.peg.3289; -.
DR EchoBASE; EB2778; -.
DR eggNOG; COG0673; Bacteria.
DR HOGENOM; CLU_023194_19_0_6; -.
DR InParanoid; P46853; -.
DR OMA; VAHIYRR; -.
DR PhylomeDB; P46853; -.
DR BioCyc; EcoCyc:G7757-MON; -.
DR EvolutionaryTrace; P46853; -.
DR PRO; PR:P46853; -.
DR Proteomes; UP000000318; Chromosome.
DR Proteomes; UP000000625; Chromosome.
DR GO; GO:0005829; C:cytosol; IDA:EcoCyc.
DR GO; GO:0000166; F:nucleotide binding; IEA:InterPro.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR InterPro; IPR004104; Gfo/Idh/MocA-like_OxRdtase_C.
DR InterPro; IPR000683; Gfo/Idh/MocA-like_OxRdtase_N.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR Pfam; PF01408; GFO_IDH_MocA; 1.
DR Pfam; PF02894; GFO_IDH_MocA_C; 1.
DR SUPFAM; SSF51735; SSF51735; 1.
PE 1: Evidence at protein level;
KW 3D-structure; Oxidoreductase; Reference proteome.
FT CHAIN 1..345
FT /note="Uncharacterized oxidoreductase YhhX"
FT /id="PRO_0000091791"
FT STRAND 3..8
FT /evidence="ECO:0007829|PDB:3F4L"
FT HELIX 12..17
FT /evidence="ECO:0007829|PDB:3F4L"
FT HELIX 19..22
FT /evidence="ECO:0007829|PDB:3F4L"
FT TURN 26..28
FT /evidence="ECO:0007829|PDB:3F4L"
FT STRAND 29..35
FT /evidence="ECO:0007829|PDB:3F4L"
FT HELIX 41..44
FT /evidence="ECO:0007829|PDB:3F4L"
FT HELIX 46..48
FT /evidence="ECO:0007829|PDB:3F4L"
FT STRAND 52..55
FT /evidence="ECO:0007829|PDB:3F4L"
FT HELIX 58..61
FT /evidence="ECO:0007829|PDB:3F4L"
FT STRAND 66..71
FT /evidence="ECO:0007829|PDB:3F4L"
FT HELIX 75..77
FT /evidence="ECO:0007829|PDB:3F4L"
FT HELIX 78..87
FT /evidence="ECO:0007829|PDB:3F4L"
FT STRAND 91..94
FT /evidence="ECO:0007829|PDB:3F4L"
FT STRAND 96..98
FT /evidence="ECO:0007829|PDB:3F4L"
FT HELIX 102..114
FT /evidence="ECO:0007829|PDB:3F4L"
FT STRAND 119..121
FT /evidence="ECO:0007829|PDB:3F4L"
FT HELIX 124..127
FT /evidence="ECO:0007829|PDB:3F4L"
FT HELIX 129..140
FT /evidence="ECO:0007829|PDB:3F4L"
FT STRAND 145..152
FT /evidence="ECO:0007829|PDB:3F4L"
FT HELIX 167..169
FT /evidence="ECO:0007829|PDB:3F4L"
FT HELIX 171..174
FT /evidence="ECO:0007829|PDB:3F4L"
FT HELIX 176..187
FT /evidence="ECO:0007829|PDB:3F4L"
FT STRAND 191..198
FT /evidence="ECO:0007829|PDB:3F4L"
FT STRAND 209..216
FT /evidence="ECO:0007829|PDB:3F4L"
FT STRAND 219..225
FT /evidence="ECO:0007829|PDB:3F4L"
FT STRAND 235..247
FT /evidence="ECO:0007829|PDB:3F4L"
FT HELIX 253..258
FT /evidence="ECO:0007829|PDB:3F4L"
FT TURN 266..269
FT /evidence="ECO:0007829|PDB:3F4L"
FT STRAND 275..280
FT /evidence="ECO:0007829|PDB:3F4L"
FT STRAND 286..291
FT /evidence="ECO:0007829|PDB:3F4L"
FT HELIX 300..311
FT /evidence="ECO:0007829|PDB:3F4L"
FT HELIX 319..331
FT /evidence="ECO:0007829|PDB:3F4L"
FT STRAND 334..342
FT /evidence="ECO:0007829|PDB:3F4L"
SQ SEQUENCE 345 AA; 38765 MW; 31D73A62511C7F68 CRC64;
MVINCAFIGF GKSTTRYHLP YVLNRKDSWH VAHIFRRHAK PEEQAPIYSH IHFTSDLDEV
LNDPDVKLVV VCTHADSHFE YAKRALEAGK NVLVEKPFTP TLAQAKELFA LAKSKGLTVT
PYQNRRFDSC FLTAKKAIES GKLGEIVEVE SHFDYYRPVA ETKPGLPQDG AFYGLGVHTM
DQIISLFGRP DHVAYDIRSL RNKANPDDTF EAQLFYGDLK AIVKTSHLVK IDYPKFIVHG
KKGSFIKYGI DQQETSLKAN IMPGEPGFAA DDSVGVLEYV NDEGVTVREE MKPEMGDYGR
VYDALYQTIT HGAPNYVKES EVLTNLEILE RGFEQASPST VTLAK
