ID   YHI1_MYCTU              Reviewed;         133 AA.
AC   P9WML3; L0T4T7; P0A5B5; P71816;
DT   16-APR-2014, integrated into UniProtKB/Swiss-Prot.
DT   16-APR-2014, sequence version 1.
DT   25-MAY-2022, entry version 44.
DE   RecName: Full=Uncharacterized HIT-like protein Rv0759c;
GN   OrderedLocusNames=Rv0759c; ORFNames=MTCY369.04c;
OS   Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv).
OC   Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC   Mycobacterium; Mycobacterium tuberculosis complex.
OX   NCBI_TaxID=83332;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 25618 / H37Rv;
RX   PubMed=9634230; DOI=10.1038/31159;
RA   Cole S.T., Brosch R., Parkhill J., Garnier T., Churcher C.M., Harris D.E.,
RA   Gordon S.V., Eiglmeier K., Gas S., Barry C.E. III, Tekaia F., Badcock K.,
RA   Basham D., Brown D., Chillingworth T., Connor R., Davies R.M., Devlin K.,
RA   Feltwell T., Gentles S., Hamlin N., Holroyd S., Hornsby T., Jagels K.,
RA   Krogh A., McLean J., Moule S., Murphy L.D., Oliver S., Osborne J.,
RA   Quail M.A., Rajandream M.A., Rogers J., Rutter S., Seeger K., Skelton S.,
RA   Squares S., Squares R., Sulston J.E., Taylor K., Whitehead S.,
RA   Barrell B.G.;
RT   "Deciphering the biology of Mycobacterium tuberculosis from the complete
RT   genome sequence.";
RL   Nature 393:537-544(1998).
RN   [2]
RP   PROTEIN SEQUENCE OF 16-42, AND SEQUENCE REVISION TO N-TERMINUS.
RC   STRAIN=H37Rv;
RX   PubMed=34915127; DOI=10.1016/j.ygeno.2021.12.001;
RA   Shi J., Meng S., Wan L., Zhang Z., Jiang S., Zhu H., Dai E., Chang L.,
RA   Gao H., Wan K., Zhang L., Zhao X., Liu H., Lyu Z., Zhang Y., Xu P.;
RT   "Deep N-terminomics of Mycobacterium tuberculosis H37Rv extensively correct
RT   annotated encoding genes.";
RL   Genomics 114:292-304(2021).
RN   [3]
RP   IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RC   STRAIN=ATCC 25618 / H37Rv;
RX   PubMed=21969609; DOI=10.1074/mcp.m111.011627;
RA   Kelkar D.S., Kumar D., Kumar P., Balakrishnan L., Muthusamy B., Yadav A.K.,
RA   Shrivastava P., Marimuthu A., Anand S., Sundaram H., Kingsbury R.,
RA   Harsha H.C., Nair B., Prasad T.S., Chauhan D.S., Katoch K., Katoch V.M.,
RA   Kumar P., Chaerkady R., Ramachandran S., Dash D., Pandey A.;
RT   "Proteogenomic analysis of Mycobacterium tuberculosis by high resolution
RT   mass spectrometry.";
RL   Mol. Cell. Proteomics 10:M111.011627-M111.011627(2011).
CC   -!- SEQUENCE CAUTION:
CC       Sequence=CCP43506.1; Type=Erroneous initiation; Note=Truncated N-terminus.; Evidence={ECO:0000269|PubMed:34915127};
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; AL123456; CCP43506.1; ALT_INIT; Genomic_DNA.
DR   PIR; B70706; B70706.
DR   RefSeq; NP_215273.3; NC_000962.3.
DR   RefSeq; WP_003403876.1; NZ_NVQJ01000035.1.
DR   AlphaFoldDB; P9WML3; -.
DR   SMR; P9WML3; -.
DR   STRING; 83332.Rv0759c; -.
DR   PaxDb; P9WML3; -.
DR   DNASU; 888776; -.
DR   GeneID; 45424724; -.
DR   GeneID; 888776; -.
DR   KEGG; mtu:Rv0759c; -.
DR   PATRIC; fig|83332.12.peg.849; -.
DR   TubercuList; Rv0759c; -.
DR   eggNOG; COG0537; Bacteria.
DR   OMA; VGLEVPH; -.
DR   Proteomes; UP000001584; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR   GO; GO:0016787; F:hydrolase activity; IBA:GO_Central.
DR   Gene3D; 3.30.428.10; -; 1.
DR   InterPro; IPR019808; Histidine_triad_CS.
DR   InterPro; IPR001310; Histidine_triad_HIT.
DR   InterPro; IPR011146; HIT-like.
DR   InterPro; IPR036265; HIT-like_sf.
DR   PANTHER; PTHR23089; PTHR23089; 1.
DR   Pfam; PF01230; HIT; 1.
DR   PRINTS; PR00332; HISTRIAD.
DR   SUPFAM; SSF54197; SSF54197; 1.
DR   PROSITE; PS00892; HIT_1; 1.
DR   PROSITE; PS51084; HIT_2; 1.
PE   1: Evidence at protein level;
KW   Direct protein sequencing; Reference proteome.
FT   CHAIN           1..133
FT                   /note="Uncharacterized HIT-like protein Rv0759c"
FT                   /id="PRO_0000109825"
FT   DOMAIN          3..106
FT                   /note="HIT"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00464"
FT   MOTIF           90..94
FT                   /note="Histidine triad motif"
SQ   SEQUENCE   133 AA;  14667 MW;  B7461C2942F4AFDF CRC64;
     MSIFTKIINR ELPGRFVYED DDVVAFLTIE PMTQGHTLVV PRAEIDHWQN VDPALFGRVM
     SVSQLIGKAV CRAFSTQRAG MIIAGLEVPH LHIHVFPTRS LSDFGFANVD RNPSPGSLDE
     AQAKIRAALA QLA