YHID_ECOLI
ID YHID_ECOLI Reviewed; 215 AA.
AC P0AFV2; P26606; Q2M7H0;
DT 20-DEC-2005, integrated into UniProtKB/Swiss-Prot.
DT 20-DEC-2005, sequence version 1.
DT 03-AUG-2022, entry version 108.
DE RecName: Full=Putative magnesium transporter YhiD;
GN Name=yhiD; Synonyms=yhhE; OrderedLocusNames=b3508, JW5670;
OS Escherichia coli (strain K12).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Escherichia.
OX NCBI_TaxID=83333;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=K12 / MG1655 / ATCC 47076;
RX PubMed=8041620; DOI=10.1093/nar/22.13.2576;
RA Sofia H.J., Burland V., Daniels D.L., Plunkett G. III, Blattner F.R.;
RT "Analysis of the Escherichia coli genome. V. DNA sequence of the region
RT from 76.0 to 81.5 minutes.";
RL Nucleic Acids Res. 22:2576-2586(1994).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=K12 / MG1655 / ATCC 47076;
RX PubMed=9278503; DOI=10.1126/science.277.5331.1453;
RA Blattner F.R., Plunkett G. III, Bloch C.A., Perna N.T., Burland V.,
RA Riley M., Collado-Vides J., Glasner J.D., Rode C.K., Mayhew G.F.,
RA Gregor J., Davis N.W., Kirkpatrick H.A., Goeden M.A., Rose D.J., Mau B.,
RA Shao Y.;
RT "The complete genome sequence of Escherichia coli K-12.";
RL Science 277:1453-1462(1997).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=K12 / W3110 / ATCC 27325 / DSM 5911;
RX PubMed=16738553; DOI=10.1038/msb4100049;
RA Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S.,
RA Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.;
RT "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655
RT and W3110.";
RL Mol. Syst. Biol. 2:E1-E5(2006).
RN [4]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-148.
RC STRAIN=K12;
RX PubMed=8455549; DOI=10.1007/bf00282791;
RA Yoshida T., Ueguchi C., Yamada H., Mizuno T.;
RT "Function of the Escherichia coli nucleoid protein, H-NS: molecular
RT analysis of a subset of proteins whose expression is enhanced in a hns
RT deletion mutant.";
RL Mol. Gen. Genet. 237:113-122(1993).
RN [5]
RP FUNCTION, AND DISRUPTION PHENOTYPE.
RX PubMed=19798051; DOI=10.1038/emboj.2009.288;
RA Hattori M., Iwase N., Furuya N., Tanaka Y., Tsukazaki T., Ishitani R.,
RA Maguire M.E., Ito K., Maturana A., Nureki O.;
RT "Mg(2+)-dependent gating of bacterial MgtE channel underlies Mg(2+)
RT homeostasis.";
RL EMBO J. 28:3602-3612(2009).
CC -!- FUNCTION: Could be involved in magnesium uptake.
CC {ECO:0000269|PubMed:19798051}.
CC -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000305}; Multi-pass
CC membrane protein {ECO:0000305}.
CC -!- DISRUPTION PHENOTYPE: Deletion of yhiD in addition to mgtA and corA
CC leads to Mg(2+) auxotrophy. {ECO:0000269|PubMed:19798051}.
CC -!- SIMILARITY: Belongs to the MgtC/SapB family. {ECO:0000305}.
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DR EMBL; U00039; AAB18484.1; -; Genomic_DNA.
DR EMBL; U00096; AAC76533.1; -; Genomic_DNA.
DR EMBL; AP009048; BAE77786.1; -; Genomic_DNA.
DR EMBL; D11109; BAA01885.1; -; Genomic_DNA.
DR PIR; S47728; S47728.
DR RefSeq; NP_417965.1; NC_000913.3.
DR RefSeq; WP_001296814.1; NZ_STEB01000046.1.
DR AlphaFoldDB; P0AFV2; -.
DR SMR; P0AFV2; -.
DR BioGRID; 4261142; 18.
DR STRING; 511145.b3508; -.
DR TCDB; 9.B.20.1.4; the putative mg(2+) transporter-c (mgtc) family.
DR jPOST; P0AFV2; -.
DR PaxDb; P0AFV2; -.
DR PRIDE; P0AFV2; -.
DR EnsemblBacteria; AAC76533; AAC76533; b3508.
DR EnsemblBacteria; BAE77786; BAE77786; BAE77786.
DR GeneID; 66672608; -.
DR GeneID; 948019; -.
DR KEGG; ecj:JW5670; -.
DR KEGG; eco:b3508; -.
DR PATRIC; fig|511145.12.peg.3615; -.
DR EchoBASE; EB1372; -.
DR eggNOG; COG1285; Bacteria.
DR HOGENOM; CLU_079292_0_1_6; -.
DR InParanoid; P0AFV2; -.
DR OMA; NHITMDP; -.
DR PhylomeDB; P0AFV2; -.
DR BioCyc; EcoCyc:EG11400-MON; -.
DR PRO; PR:P0AFV2; -.
DR Proteomes; UP000000318; Chromosome.
DR Proteomes; UP000000625; Chromosome.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005886; C:plasma membrane; IDA:EcoCyc.
DR InterPro; IPR003416; MgtC/SapB/SrpB/YhiD_fam.
DR PANTHER; PTHR33778; PTHR33778; 1.
DR Pfam; PF02308; MgtC; 1.
DR PRINTS; PR01837; MGTCSAPBPROT.
PE 3: Inferred from homology;
KW Cell inner membrane; Cell membrane; Magnesium; Membrane;
KW Reference proteome; Transmembrane; Transmembrane helix; Transport.
FT CHAIN 1..215
FT /note="Putative magnesium transporter YhiD"
FT /id="PRO_0000202032"
FT TRANSMEM 1..21
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 36..56
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 67..87
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 92..112
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 118..138
FT /note="Helical"
FT /evidence="ECO:0000255"
SQ SEQUENCE 215 AA; 23213 MW; 4F3E986281C3CF99 CRC64;
MTAEFIIRLI LAAIACGAIG MERQMRGKGA GLRTHVLIGM GSALFMIVSK YGFADVLSLD
HVGLDPSRIA AQVVTGVGFI GAGNILVRNQ NIVGLTTAAD IWVTAAIGMV IGSGMYELGI
YGSVMTLLVL EVFHQLTFRL MNKNYHLQLT LVNGNTVSML DWFKQQKIKT DLVSLQENED
HEVVAIDIQL HATTSIEDLL RLLKGMAGVK GVSIS
